Tirzepatide side chain TBuO-Ara-Glu(AEEA-AEEA-OH)-OtBu
2 Inquiries
1188328-37-1
Pharmaceutical Grade
90%
Shanghai or Beijing
HANDOM CHEM
1g/Bottle, 5g/Bottle, 10g/Bottle or according to the specific requirements from customers
2023-12-30
Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine
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Product Description
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceAra(OtBu)-Glu(ɑ-OtBu)-AEEA-AEEA-OH (C20-OtBu-Glu(OtBu)-AEEA-AEEA-OH) is a intermediate for Tirzepatide fragment synthesis.
C20-OtBu-Glu(OtBu)-AEEA-AEEA-OH (CAS 1188328-37-1), also known as tBuO-Ara-Glu(AEEA-AEEA-OH)-OtBu, is a high-purity semaglutide intermediate.Basic Info-
Product Name:
C20-OtBu-Glu(OtBu)-AEEA-AEEA-OH
Other Name:LY1001;3,6,12,15-Tetraoxa-9,18-diazatricosanedioic acid, 22-[[20-(1,1-dimethylethoxy)-1,20-dioxoeicosyl]amino]-10,19-dioxo-, 23-(1,1-dimethylethyl) ester, (22S)-;Eico(OtBu)-Glu(OtBu)-AEEA-AEEA;C20-OtBu-Glu(OtBu)-AEEA-AEEA-OH;22-[[20-(1,1-dimethylethoxy)-1,20-dioxoeicosyl]amino]-10,19-dioxo-, 23-(1,1-dimethylethyl) ester;C20-OtBu-Glu(OtBu)-AEEA-AEEA-OH,Tirzepatide sidechain;Ara(OtBu)-Glu(ɑ-OtBu)-AEEA-AEEA-OH;Sermaglutide Intermediate
CAS No.:1188328-37-1
Molecular Formula:C45H83N3O13
InChIKeys:WFSAVPRDBQIQAX-QNGWXLTQSA-N
Molecular Weight:874.15
Categories:
Characteristics-
Density:
1.070±0.06 g/cm3(Predicted)
Boiling Point:953.8±65.0 °C(Predicted)
PKA:3.39±0.10(Predicted)
Research-
Class:
Dual agonist — GIPR, GLP-1R
Status:FDA-approved (Mounjaro / Zepbound)
Mechanism:Dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. A 39-amino-acid modified peptide with a C20 fatty diacid moiety that enables albumin binding for extended half-life (~5 days). Selectively activates both GIPR and GLP-1R signaling pathways.
EC50 (Human GLP1R):0.934 nM
EC50 (Human GIPR):0.0224 nM
Source:Frias JP, et al. N Engl J Med. 2021;385(6):503-515.DOI
Clinical Development:NCT03954834; NCT03987919; NCT03882970; NCT03730662; NCT04039503
FDA:Mounjaro, Zepbound (approved 2022-05-13)
References-
ChEMBL:DrugBank:KEGG DRUG:PubChem:Disclaimer:
Tirzepatide is approved as a prescription medicine (Mounjaro, Zepbound) in certain jurisdictions. This listing is for industrial and laboratory research use only. Research-chemical listings on B2B marketplaces are not interchangeable with approved medicines. Confirm CAS, specification, and regulatory pathway with the seller. It is not medical advice, a clinical recommendation, or an approved therapy description.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Semaglutide,Tirzepatide,HCG,Retatrutide,Cagrilintide,Medetomidine
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Location:
RM702, Building 21, Liuhe Road, Ganjingzi Dist, Dalian, Liaoning, China
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Payment Terms:
TT against copy of documents,L/C,TT against B/L draft before shipment,100% TT in advance
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Average lead Time:
15 days
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Total Annual Revenue:
$5 million-$10 million
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Total Employees:
51-100
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Year of Establishment:
2020
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Inquiry History2 Inquiries
Country Product Purchase Quantity Date Posted
United States
C20-OtBu-Glu(OtBu)-AEEA-AEEA-OH
100 G Feb 27, 2024
India
C20-OtBu-Glu(OtBu)-AEEA-AEEA-OH
1.50 KG Sep 12, 2025 Post an enquiry for this product
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