 Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > 1H-Pyrazolo[3,4-d]pyrimidin-4-amine for Sale > 2380-63-4 | ChemExpress

2380-63-4 | ChemExpress

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CAS No.:

2380-63-4

Port:

shanghai

Packaging:

10 kg

Price valid (until):

2024-04-01

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ChemExpress

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

CRO

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Product Description
Seller Information

Description

Pyrazoloadenine

Intermediate of BTK inhibitor 3 for BTK inhibitors
We can provide high-quality Pyrazoloadenine and its derived impurities.

Brand：ChemExpress
CAS：2380-63-4
Catalog_No：HY-34595
Molecular Formular:C5H5N5
Molecular Weight:135.13

Contact:
TEL：+1-970-439-2030 (USA)、+86 (21) 5895-0125 (Global)
Email：info@chemexpress.com

Brand Introduction:
ChemExpress focuses on providing small molecule and new modalities CDMO services for both pharmaceutical and biotech clients. Our comprehensive CRO & CDMO platform is engaged in the research and development, manufacturing and supply of regulatory starting materials, novel building blocks, intermediates, reference compounds, APIs and drug products. We are a one-stop service platform to support our client’s projects from early drug discovery, process development to commercialization.

ChemExpress Services:

Drug Discovery: synthetic chemistry; medicine chemistry; FTE/FFS services.

Process Development: APIs and intermediates development; formulation development.

New Modalities Development: ADC; peptide; oligonucleotide and so on.

Manufactory: support production from milligrams to kilograms, both with GMP and non-GMP capabilities.

Analytical Development & Quality Control: R&D testing; stability study; genotoxic impurity research and so on.

Regulatory CMC Support

Eany development services in Synthetic Chemistny:Providing serices related to high qualty compound synthesis,chemical custom synthesis and analytical chemistry.

Pharmaceutical Chemistry eaniy development services: including high-throughput screening, drug synthesis, seding compounds, lead compounds, and IND fling support.

Process development: Covers AP! & intermediates process development, validation, transfer, and formulation development.

Commerial producion:it hasa research and development base forthe producion otapis intermediates and prenarations and provdes commeria prouction semices.

CMC services: Provide one-stop CMC services, from lND to NDA stage of pharmaceutical research and development and dedlaration services, accelerate IND declaration.

ADC drug and highly active drug development and production: Provides a one-stop CRO & CDMO service for the small molecule aspect of ADC drugs, as well as customized ADC conjugation services.

Oligonucleotide drug process development and production: Provide oligonucleotide customized products and services to meet different needs.

Analytical testing services and quality control: Provide integrated analytical testing services and drug quality research support

ChemExpress committed to being a steadfast companion for our clients, gaining profound insight into their needs. Our focus is on accelerating the empowerment of global partners across the full spectrum, from preclinical stages to commercial production. This commitment aims for more streamlined drug development, swifter market entry, and an earlier positive impact on human health.

Product details：https://www.chemexpress.com/product/HY-34595

Basic Info

Product Name:

1H-Pyrazolo[3,4-d]pyrimidin-4-amine

Other Name:

1H-Pyrazolo[3,4-d]pyrimidin-4-amine;1H-Pyrazolo[3,4-d]pyrimidine,4-amino-;4-Aminopyrazolo[3,4-d]pyrimidine;4-Amino-1H-pyrazolo[3,4-d]pyrimidine;8-Aza-7-deazaadenine;1H-Pyrazolo[3,4-d]pyrimidin-4-ylamine;NSC 1393;7-Deaza-8-azaadenine;7-Deaza-8-aza-adenine

CAS No.:

2380-63-4

Molecular Formula:

C5H5N5

InChIKeys:

InChIKey=LHCPRYRLDOSKHK-UHFFFAOYSA-N

Molecular Weight:

193.671

Exact Mass:

135.13

EC Number:

243-691-6

UNII:

0356MAT9LX

NSC Number:

1393

DSSTox ID:

DTXSID3062362

HScode:

2933990090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

80.48000

XLogP3:

-0.2

Appearance:

Beige powder.

Density:

1.612g/cm3

Melting Point:

353-356 °C

Boiling Point:

431.1ºC at 760mmHg

Flash Point:

244.4ºC

Water Solubility:

Insoluble in water.

Storage Conditions:

Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

Toxicity:

LD50 oral in rat: 141mg/kg

See More 1H-Pyrazolo[3,4-d]pyrimidin-4-amine Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity â single exposure, Category 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell.
Storage	P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More 1H-Pyrazolo[3,4-d]pyrimidin-4-amine Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
CRO

Location:
1 Deer Park Dr, Suite Q, Monmouth Junction, NJ 08852, USA

Payment Terms:
TT against copy of documents

Average lead Time:
3

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
Above 1000

Year of Establishment:
2006

Company Profile
Founded in 2006, ChemExpress focuses on providing small molecule and new modalities CDMO services for both pharmaceutical and biotech clients. Our comprehensive CRO & CDMO platform is engaged in the research and development, manufacturing and supply of regulatory starting materials, novel building blocks, intermediates, reference compounds, APIs and drug products. We are a one-stop service platform to support our client’s projects from early drug discovery, process development to commercialization.

Over the past 17 years, we have established a state-of-the-art QC/QA system aligning with ICH guidelines for pharmaceutical manufacturing. We provide our clients with high-quality products and CMC services across the entire life-cycle of drug development.
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