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ISO Certified Reference Material LITHOCHOLIC ACID Purity Degree 99%

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CAS No.:

434-13-9

Grade:

Pharmaceutical Grade

Content:

99%

Port:

SHANGHAI

Brand:

Packaging:

1kg 5kg

Sample Available:

Yes

Price valid (until):

2024-05-09

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Dingyanchem

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,D/P,L/C,D/A,TT against B/L draft before shipment

Average Lead Time:

20 days

Qualification:

Main Products:

Pharmaceutical materials (APIs),Pharmaceutical Intermediates,Fine chemicals,Biochemical reagents

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Product Description
Seller Information

Description

Product Detail

Appearance	This product should be off white powder with strong hygroscopicity	Conforms
Loss on drying	≤1.0%	0.6%
Specifies rotation	+33.7°~ +40°	+36.5°
Heavy metal	≤20ppm	9ppm
Residue on ignition	≤0.5%	0.3%
Chloride	≤0.2%	0.14%
Melting point	183℃-188℃	185℃
Assay	≥98.0%	98.2%
Conclusion	Qualified

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Q1 Can i get some samples
A1 Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2 How to start orders or make payments
A2 Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T,or Paypal or Escrow(Alibaba).
Q3 How to confirm the Product Quality before placing orders
A3 You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q4 What's your MOQ
A4 Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5 How about delivery leadtime
A5 Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6 Is there a discount
A6 Different quantity has different discount.
Q7 How do you treat quality complaint
A7 First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q8 How to contact us
A9 You can chat with us by Trademanager,MSN&Skype Online.
You can choose your interested products and send inquiry to us.
You can dial our telephone directly or send Email to us., you will get our reply.

ECHEMI Editorial Reference

Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity.Target: OthersLithocholic acid has been used in a study to assess cholestasis and its action on several organs and tissues in rats. It has also been used in a study to investigate the regulation of hepatic phospholipid and bile acid homeostasis through SMAD3 activation by TGFβ. It has been implicated in human and experimental animal carcinogenesis. Preliminary in vitro research
Hexagonal leaflets (from alcohols) or prisms (from acetic acid) or white powder. (NTP, 1992)|Solid
Hexagonal leaflets (from alcohols) or prisms (from acetic acid) or white powder. (NTP, 1992)|Lithocholic acid is a monohydroxy-5beta-cholanic acid with a alpha-hydroxy substituent at position 3. It is a bile acid obtained from chenodeoxycholic acid by bacterial action. It has a role as a human metabolite, a mouse metabolite and a geroprotector. It is a bile acid, a monohydroxy-5beta-cholanic acid and a C24-steroid. It is a conjugate acid of a lithocholate.|A bile acid formed from chenodeoxycholate by bacterial action, usually conjugated with glycine or taurine. It acts as a detergent to solubilize fats for absorption and is itself absorbed. It is used as cholagogue and choleretic.

Certificates

Basic Info

Product Name:

Lithocholic acid

Other Name:

Cholan-24-oic acid,3-hydroxy-,(3α,5β)-;5β-Cholan-24-oic acid,3α-hydroxy-;5β-Cholanic acid,3α-hydroxy-;(3α,5β)-3-Hydroxycholan-24-oic acid;3α-Hydroxycholanic acid;3α-Hydroxy-5β-cholanic acid;Lithocholic acid;3α-Hydroxy-5β-cholanoic acid;3α-Hydroxy-5β-cholan-24-oate;3-Hydroxycholan-24-oic acid;17β-(1-Methyl-3-carboxypropyl)etiocholan-3α-ol;3α-Hydroxy-5β-cholan-24-oic acid;NSC 683770;2360921-71-5

CAS No.:

434-13-9

Molecular Formula:

C24H40O3

InChIKeys:

InChIKey=SMEROWZSTRWXGI-HVATVPOCSA-N

Molecular Weight:

376.57

Exact Mass:

376.57

EC Number:

207-099-1

UNII:

5QU0I8393U

NSC Number:

683770

DSSTox ID:

DTXSID6020779

Color/Form:

HEXAGONAL LEAFLETS FROM ALC, PRISMS FROM ACETIC ACID

HScode:

29181998

Categories:

Inhibitor Drugs

Characteristics

PSA:

57.5

XLogP3:

6.70

Appearance:

White to off-white Powder

Density:

1.1±0.1 g/cm3

Melting Point:

184-186 °C

Boiling Point:

511.0±23.0 °C at 760 mmHg

Flash Point:

9℃

Refractive Index:

35.5 ° (C=1, EtOH)

Water Solubility:

18.83ug/L(25 ºC)

Storage Conditions:

Refrigerator

Specific rotation:

D20 +33.7° (c = 1.5 in abs ethanol); D19 +23.3° (Wieland); D20 +32.1° (Fischer)

Collision Cross Section:

193.4 Å² [M+H-H2O]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|199.95 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|200.33 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|203.1 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|210.8 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|198.9 Å² [M-H]- [CCS Type: DT, Method: single field calibrated]|191.6 Å² [M+H-H2O]+ [CCS Type: DT, Method: single field calibrated]|198.8 Å² [M+HCOO]- [CCS Type: DT, Method: single field calibrated]|204.1 Å² [M+K-H+HCOO]- [CCS Type: DT, Method: single field calibrated]|217.6 Å² [M+K-H+HCOO]- [CCS Type: DT, Method: single field calibrated]|197.9 Å² [M+Na-H+Cl]- [CCS Type: DT, Method: single field calibrated]|201.6 Å² [M+Na-H+HCOO]- [CCS Type: DT, Method: single field calibrated]|214.8 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated]|201.4 Å² [M-H]-

Experimental Properties:

CRYSTALS /ETHYL ESTER/|CRYSTALS /BENZYL ESTER/|CRYSTALS /ACETYLLITHOCHOLIC ACID/|FLAT NEEDLES FROM PENTANE /ACETYLLITHOCHOLIC ACID METHYL ESTER/|For more Other Experimental Properties (Complete) data for LITHOCHOLIC ACID (6 total), please visit the HSDB record page.

Air and Water Reactions:

Insoluble in water.

Reactive Group:

Acids, Carboxylic

See More Lithocholic acid Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Lithocholic acid Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceutical materials (APIs),Pharmaceutical Intermediates,Fine chemicals,Biochemical reagents

Location:
Room 601, Building 4,No.571, Str.19, Hangzhou, Zhejian

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,TT against B/L draft before shipment

Average lead Time:
20 days

Total Annual Revenue:
Less than $1 million

Total Employees:
11-50

Year of Establishment:
2013

Company Certificates
- Hazardous Chemicals Production License
- Business license
Company Profile
Located in Xiasha Economic Development Park of Hangzhou city (capital of Zhejiang province in the southeast coastal region of China), Hangzhou Dingyan Chem Co.,Ltd is a modern private enterprise; we are mainly engaged in the development, trade and independent.import and export business of hi-tech products such as pharmaceutical materials (APIs), pharmaceutical intermediates, fine chemicals and biochemical reagents, etc. Insisting on the development path of “scientific and technological innovation” since our foundation, we has laid great stresses on the research and development of scientific and technological innovation. Now, our products are well sold in more than 60 countries and regions in North America, Western Europe, Southeast Asia, Central and South America, and then established long-term and steady relations of cooperation with many pharmaceutical enterprises in Europe, USA, Greece, Germany, South Korea and India, etc. WE are highly appraised and trusted by customers for rigorous attitude and sincere service. Taking “market as guidance, technological innovation as support, and environmental protection and safety as mission, to build brand image by honest business and dedicated work”, we are committed to the development of biochemicals and fine chemicals, etc.
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ISO Certified Reference Material LITHOCHOLIC ACID Purity Degree 99%

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

More Choices Find All Products for Sale 

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