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Home > Biochemical Engineering > Amino Acids and Derivatives > L-Phenylalanine for Sale > High Quality CAS 63-91-2 L Phenylalanine Powder Best Price L Phenylalanine Raw Material L Phenylalanine
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High Quality CAS 63-91-2 L Phenylalanine Powder Best Price L Phenylalanine Raw Material L Phenylalanine

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Unit Price: Get Latest Price
CAS No.:

63-91-2

Grade:

Industrial Grade

Content:

99%

Port:

Durban

Brand:

Custom

Packaging:

As per customer requirement

Price valid (until):

2024-05-19

Company Type:
Distributor
Location:
South Africa
Payment Terms:
TT against copy of documents,TT against B/L draft before shipment
Average Lead Time:
60 days
Qualification:
Main Products:

Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Phenylalanine (167088-01-9): Exploring the Essential Amino Acid's Functions, Sources, and Biomedical Significance

    Phenylalanine, with the chemical identifier 167088-01-9, stands as one of the essential amino acids crucial for numerous physiological processes in living organisms. Its structural characteristics, metabolic pathways, and biomedical implications underscore its significance in nutrition, biochemistry, and medicine.

    1. Essential Amino Acid: Phenylalanine is classified as an essential amino acid, meaning it cannot be synthesized by the human body and must be obtained through dietary sources. It serves as a fundamental building block for protein synthesis and participates in various metabolic pathways essential for cellular function and homeostasis.

    2. Structural Foundation: Phenylalanine features a benzyl side chain, conferring hydrophobicity and aromaticity to its chemical structure. This aromatic ring system distinguishes phenylalanine from other amino acids and contributes to its diverse biochemical properties and physiological functions.

    3. Metabolic Pathways: Phenylalanine serves as a precursor for the synthesis of tyrosine, another amino acid essential for protein synthesis and various biochemical reactions. The conversion of phenylalanine to tyrosine occurs via the enzymatic action of phenylalanine hydroxylase, a critical step in the phenylalanine metabolic pathway.

    4. Neurotransmitter Synthesis: In addition to its role in protein synthesis, phenylalanine plays a crucial role in neurotransmitter synthesis, serving as a precursor for the production of dopamine, norepinephrine, and epinephrine. These neurotransmitters are essential for neuronal communication, mood regulation, and cognitive function.

    5. Dietary Sources: Phenylalanine is abundantly found in protein-rich foods such as meat, fish, eggs, dairy products, legumes, nuts, and seeds. Dietary intake of phenylalanine is essential for meeting daily nutritional requirements and supporting optimal health and wellbeing.

    6. Phenylketonuria (PKU): Disorders in phenylalanine metabolism, such as phenylketonuria (PKU), can lead to the accumulation of phenylalanine and its metabolites in the body, resulting in neurological and developmental abnormalities. Early detection and management of PKU through dietary restriction of phenylalanine are crucial for preventing cognitive impairment and other associated complications.

    7. Biomedical Applications: Phenylalanine and its derivatives have been investigated for their potential therapeutic applications in various medical conditions, including chronic pain management, mood disorders, and neurodegenerative diseases. Phenylalanine supplementation, in combination with other therapeutic modalities, may offer therapeutic benefits in specific patient populations.

    8. Safety Considerations: While phenylalanine is essential for health, excessive intake or accumulation of phenylalanine can have adverse effects, particularly in individuals with phenylketonuria or certain metabolic disorders. Careful monitoring of phenylalanine intake and adherence to dietary restrictions are essential for managing these conditions and preventing complications.

    Conclusion: Phenylalanine stands as a foundational amino acid with critical roles in protein synthesis, neurotransmitter metabolism, and overall physiological function. Its contributions to human health and disease highlight the importance of understanding phenylalanine's metabolism, dietary sources, and biomedical implications for promoting optimal nutrition and personalized healthcare.


      Specifications  


    Items Specifications
    Chemical Structure Phenylalanine is an α-amino acid with the chemical formula C9H11NO2. It consists of a phenyl group attached to an amino group.
    2. Essential Amino Acid Phenylalanine is an essential amino acid, meaning it cannot be synthesized by the body and must be obtained from the diet.
    3. Dietary Sources It is found in protein-rich foods such as meat, fish, eggs, dairy products, soybeans, nuts, seeds, and certain grains.
    4. Protein Synthesis Phenylalanine is one of the building blocks of proteins and is incorporated into polypeptide chains during protein synthesis.
    5. Tyrosine Conversion Phenylalanine can be converted into tyrosine, another amino acid, by the enzyme phenylalanine hydroxylase.
    6. Neurotransmitter Tyrosine derived from phenylalanine serves as a precursor for neurotransmitters such as dopamine, norepinephrine, and epinephrine.
    7. Phenylketonuria (PKU) Individuals with phenylketonuria lack the enzyme needed to metabolize phenylalanine properly, leading to toxic buildup and neurological damage.
    8. Sweetener L-Phenylalanine, one of the isomers of phenylalanine, is used as a low-calorie sweetener in products like diet sodas and sugar-free gum.
    9. Cognitive Function Phenylalanine is believed to play a role in cognitive function and mood regulation, as it affects the synthesis of neurotransmitters in the brain.
    10. Supplementation Phenylalanine supplements are sometimes used to alleviate symptoms of depression, attention deficit hyperactivity disorder (ADHD), and chronic pain.
    11. Regulation In some countries, foods containing phenylalanine must be labeled to alert individuals with phenylketonuria (PKU) to their presence.
    12. Phenylalanine Hydroxylase This enzyme catalyzes the conversion of phenylalanine to tyrosine and is crucial for maintaining proper phenylalanine levels in the body.
    13. Protein Deficiency Inadequate intake of phenylalanine and other essential amino acids can lead to protein deficiency and impaired growth and development.
    14. Research Interest Phenylalanine metabolism and its role in health and disease continue to be areas of active research in fields such as nutrition, biochemistry, and medicine.
    15. Safety Considerations While phenylalanine is generally safe when consumed in dietary amounts, excessive intake from supplements may lead to adverse effects such as headaches and nausea.






      Product Detail  



    Shop Most Professional Factory Supply High Qulity PHYTOHEMAGGLUTININ PHA-M CAS 9008-97-3-Detailed Image 1Shop High Quality CAS 63-91-2 L Phenylalanine Powder Best Price L Phenylalanine Raw Material L Phenylalanine-Detailed Image 2

    ECHEMI Editorial Reference
    L-Phenylalanine is an antagonist at α2δ calcium channels with a Ki of 980 nM. IC50 Value: 980 nM [1]Target: Calcium ChannelL-Phenylalanine (LPA) is an electrically neutral amino acid, one of the twenty common amino acids used to biochemically form proteins. In the brain, L-phenylalanine is a competitive antagonist at the glycine binding site of NMDA receptor and at the glutamate binding site of AMPA receptor [2, 3]. At the glycine binding site of NMDA receptor L-phenylalanine has an appa
    L-phenylalanine is an odorless white crystalline powder. Slightly bitter taste. pH (1% aqueous solution) 5.4 to 6. (NTP, 1992)|DryPowder|Solid|Colourless or white platelike crystals or crystalline powder; odourless
    L-phenylalanine is an odorless white crystalline powder. Slightly bitter taste. pH (1% aqueous solution) 5.4 to 6. (NTP, 1992)|L-phenylalanine is the L-enantiomer of phenylalanine. It has a role as a nutraceutical, a micronutrient, an Escherichia coli metabolite, a Saccharomyces cerevisiae metabolite, a plant metabolite, an algal metabolite, a mouse metabolite, a human xenobiotic metabolite and an EC 3.1.3.1 (alkaline phosphatase) inhibitor. It is an erythrose 4-phosphate/phosphoenolpyruvate family amino acid, a proteinogenic amino acid, a phenylalanine and a L-alpha-amino acid. It is a conjugate base of a L-phenylalaninium. It is a conjugate acid of a L-phenylalaninate. It is an enantiomer of a D-phenylalanine. It is a tautomer of a L-phenylalanine zwitterion.|Phenylalanine is an essential aromatic amino acid that is a precursor of melanin, [dopamine], [noradrenalin] (norepinephrine), and [thyroxine].|Phenylalanine is an essential aromatic amino acid in humans (provided by food), Phenylalanine plays a key role in the biosynthesis of other amino acids and is important in the structure and function of many proteins and enzymes. Phenylalanine is converted to tyrosine, used in the biosynthesis of dopamine and norepinephrine neurotransmitters. The L-form of Phenylalanine is incorporated into proteins, while the D-form acts as a painkiller. Absorption of ultraviolet radiation by Phenylalanine is used to quantify protein amounts. (NCI04)|An essential aromatic amino acid that is a precursor of MELANIN; DOPAMINE; noradrenalin (NOREPINEPHRINE), and THYROXINE.

    Basic Info
    Product Name:

    L-Phenylalanine

    Other Name:

    L-Phenylalanine;Alanine,phenyl-,L-;(S)-α-Aminohydrocinnamic acid;(S)-α-Amino-β-phenylpropionic acid;Phenylalanine;β-Phenyl-L-alanine;β-Phenyl-α-alanine;Antibiotic FN 1636;Benzenepropanoic acid,α-amino-,(S)-;Phenyl-α-alanine;3-Phenyl-L-alanine;3-Phenylalanine;(S)-Phenylalanine;(S)-α-Aminobenzenepropanoic acid;(S)-2-Amino-3-phenylpropionic acid;L-Alanine,3-phenyl-;(S)-2-Amino-3-phenylpropanoic acid;(S)-(-)-Phenylalanine;(-)-Phenylalanine;L-(-)-Phenylalanine;NSC 79477;(2S)-2-Amino-3-phenylpropanoic acid;(2s)-2-Amino-3-phenylpropanoic acid;3617-44-5;5297-02-9;10549-09-4;67675-33-6;801204-11-5;2416148-28-0

    CAS No.:

    63-91-2

    Molecular Formula:

    C9H11NO2

    InChIKeys:

    InChIKey=COLNVLDHVKWLRT-QMMMGPOBSA-N

    Molecular Weight:

    165.18900

    Exact Mass:

    165.19

    EC Number:

    200-568-1

    UNII:

    47E5O17Y3R

    DSSTox ID:

    DTXSID4040763

    NCI Thesaurus Code:

    C29601

    Color/Form:

    Prisms form water|Monoclinic plates, leaflets from warm concentrated aqueous solution; hydrated needles from dilute solutions

    HScode:

    29224995

    Characteristics
    PSA:

    63.32000

    XLogP3:

    1.34130

    Appearance:

    L-phenylalanine is an odorless white crystalline powder. Slightly bitter taste. pH (1% aqueous solution) 5.4 to 6. (NTP, 1992)

    Density:

    1.24 g/cm3

    Melting Point:

    283 °C (decomp)

    Boiling Point:

    307.5ºC at 760 mmHg

    Flash Point:

    139.8ºC

    Refractive Index:

    1.576

    Water Solubility:

    1-5 g/100 mL at 25 ºC

    Storage Conditions:

    Store at RT.

    Vapor Pressure:

    <1 Pa (25 °C)

    Specific rotation:

    Specific optical rotation: -35.1 deg at 20 °C/D (c = 1.94)

    Odor:

    Slight

    Taste:

    Bitter

    PKA:

    1.24(at 25 °C)

    Henrys Law Constant:

    Henry's Law constant = 1.2X10-10 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    1.24 (at 25 °C)|pK1 = 1.83; pK2 = 9.13|pKa = 1.24

    Collision Cross Section:

    140.3 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|138.91 Ų [M+Na]+ [CCS Type: DT, Method: stepped-field]|146.52 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|135 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|140.2 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|138.3 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|139.4 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|141.29 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|141.28 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|140.1 Ų [M-H]-

    Experimental Properties:

    Sublimes in vacuo|Leaflets from water, decomposes at 285 °C. Specfic optical rotation: +35.0 deg at 20 °C/D (c = 2.04); +7.1 deg at 20 °C/D (c = 3.8 in 18% HCl). One gram dissolves in 35.5 mL water at 16 °C. Sparingly soluble in methanol /Phenylalanine D-form/|OCCURS IN ISOMERIC FORMS /PHENYLALANINE/

    Air and Water Reactions:

    Water soluble. Aqueous solutions are weak acids.

    Reactive Group:

    Salts, Acidic

    Reactivity Profile:

    L-PHENYLALANINE may be light sensitive. Acts as a weak acid in solution.

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid

    Location:

    13 PROTEA PARK MILKWOOD STREET RANGEVIEW GAUTENG 1739

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment

    Average lead Time:

    60 days

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2012

  • Inquiry History
    8 Inquiries
    Country Product Purchase Quantity Date Posted
    United Kingdom

    L-phenylalanine 63-91-2

    200 KG Jan 29, 2024
    India

    L-Phenylalanine

    25 KG Apr 21, 2025
    United Kingdom

    L-phenylalanine

    1 MT Dec 18, 2024
    India

    L-Phenylalanine

    15 KG Sep 25, 2023
    Greece

    PHENYLALANINE (Phe, F)

    1000.00 KG Sep 25, 2025
    India

    L-Phenylalanine

    1 MT Apr 23, 2025
    Ireland

    Phenyl Alanine

    5 TON May 27, 2025
    United Kingdom

    L-phenylalanine CAS 63-91-2

    200 KG Jan 26, 2024
    Post an enquiry for this product
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