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High Quality Berberine hydrochloride 99% powder 633-65-8 In Bulk

6 Inquiries

Unit Price: Get Latest Price
CAS No.:

633-65-8

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Durban

Brand:

Custom

Packaging:

As per customer requirement

Price valid (until):

2024-05-27

Company Type:
Distributor
Location:
South Africa
Qualification:
Main Products:

Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


                                                                  1. Chemical Structure: Berberine hydrochloride is an isoquinoline alkaloid, characterized by a bright yellow color and a bitter taste.

                                                                  2. Chemical Formula: Its chemical formula is C20H18ClNO4.

                                                                  3. Solubility: Berberine hydrochloride is soluble in water, ethanol, and other polar solvents.

                                                                  4. Natural Sources: It is commonly found in various plants, including goldenseal, barberry, and Oregon grape.

                                                                  5. Traditional Medicine: Berberine hydrochloride has been used in traditional Chinese and Ayurvedic medicine for centuries due to its purported medicinal properties.

                                                                  6. Pharmacological Activities: It exhibits a wide range of pharmacological activities, including antimicrobial, anti-inflammatory, antidiabetic, and anticancer properties.

                                                                  7. Antimicrobial Effects: Berberine hydrochloride has demonstrated effectiveness against a variety of bacteria, fungi, protozoa, and viruses, making it a valuable antimicrobial agent.

                                                                  8. Anti-inflammatory Properties: Studies have shown that it can inhibit inflammatory pathways, potentially offering relief from conditions such as arthritis and inflammatory bowel disease.

                                                                  9. Antidiabetic Effects: Berberine hydrochloride has been found to improve insulin sensitivity, lower blood sugar levels, and regulate lipid metabolism, making it useful in the management of diabetes.

                                                                  10. Anticancer Potential: Research suggests that Berberine hydrochloride may inhibit cancer cell proliferation and induce apoptosis in various types of cancer, including breast, prostate, and colon cancer.

                                                                  11. Cardiovascular Benefits: It has been reported to have cardioprotective effects, including the ability to lower cholesterol levels and reduce the risk of cardiovascular diseases.

                                                                  12. Neuroprotective Properties: Some studies indicate that Berberine hydrochloride may possess neuroprotective effects, potentially offering benefits in neurodegenerative diseases like Alzheimer's and Parkinson's.

                                                                  13. Safety Considerations: While generally considered safe when used at appropriate doses, Berberine hydrochloride may cause gastrointestinal side effects in some individuals, especially at higher doses.

                                                                  14. Drug Interactions: It may interact with certain medications, such as antibiotics, anticoagulants, and antidiabetic drugs, so caution should be exercised when combining them.

                                                                  15. Research Trends: Ongoing research is exploring the therapeutic potential of Berberine hydrochloride in various health conditions and its mechanisms of action at the molecular level.

    Items Specifications
    Chemical Name Berberine hydrochloride
    Chemical Formula C20H18ClNO4
    CAS Number 633-65-8
    Molecular Weight 371.82 g/mol
    Appearance Yellow crystalline powder
    Odor Odorless
    Melting Point 145-146°C
    Boiling Point Decomposes
    Solubility in Water Soluble
    Solubility in Organic Solvents Slightly soluble
    pH (aqueous solution) Not applicable
    Density 1.275 g/cm³
    Flash Point Not applicable
    Storage Conditions Store in a cool, dry place away from heat and light. Keep container tightly closed.
    Common Uses Berberine hydrochloride is a salt form of berberine, an alkaloid found in several plants. It has been used in traditional medicine for its various pharmacological properties, including antibacterial, antifungal, antiviral, and anti-inflammatory effects. It is also being studied for its potential in treating various diseases such as diabetes, cardiovascular conditions, and cancer.



      Product Detail  


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    Basic Info
    Product Name:

    Berberine hydrochloride

    Other Name:

    Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-,chloride (1:1);Berbinium,7,8,13,13a-tetradehydro-9,10-dimethoxy-2,3-(methylenedioxy)-,chloride;Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizinium,5,6-dihydro-9,10-dimethoxy-,chloride;Berberine,chloride;Berberine hydrochloride;Berberinium chloride;NSC 646666;NSC 163088;Berberine IR;16,17-Dimethoxy-5,7-dioxa-13λ5-azapentacyclo[11.8.0.0[2,10].0[4,8].0[15,20]]henicosa-1(21),2(10),3,8,13,15(20),16,18-octaen-13-ylium chloride;1082532-96-4

    CAS No.:

    633-65-8

    Molecular Formula:

    C20H18NO4.Cl

    InChIKeys:

    InChIKey=VKJGBAJNNALVAV-UHFFFAOYSA-M

    Molecular Weight:

    371.81400

    Exact Mass:

    371.09200

    EC Number:

    211-195-9

    UNII:

    UOT4O1BYV8

    NSC Number:

    757795|163088|646666

    DSSTox ID:

    DTXSID8024602

    NCI Thesaurus Code:

    C87331

    HScode:

    3003409000

    Categories:

    Plant Extracts

    Characteristics
    PSA:

    40.80000

    XLogP3:

    0.10030

    Appearance:

    yellow crystalline powder

    Density:

    1.654g/cm3

    Melting Point:

    214 °C

    Water Solubility:

    soluble in cold water

    Storage Conditions:

    Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from

    Toxicity:

    LD50 orl-rat: >15 g/kg KSRNAM 8,654,74

    Collision Cross Section:

    175.9 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    Sodium Lauryl Ether Sulfate,Caustic Soda,Soda Ash,Citric Acid,Calcium Hypochlorite,Oxalic Acid

    Location:

    13 PROTEA PARK MILKWOOD STREET RANGEVIEW GAUTENG 1739

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment

    Average lead Time:

    60

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2012

  • Inquiry History
    6 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Good sales product cas 633-65-8 Berberine hydrochloride yellow powder

    250 KG Sep 20, 2023
    Netherlands

    Berberine Hydrochloride

    1000 KG May 12, 2026
    India

    Berberine hydrochloride

    1000 KG Dec 7, 2023
    United States

    Berberine Hydrochloride CAS 141433-60-5 Berberine HCl Powder

    1 MT Jul 18, 2023
    United Kingdom

    Berberine HCl 95% Yellow Brown powder Arshine

    250 KG Jun 3, 2023
    United States

    Berberine HCl 95% Yellow Brown powder Arshine

    25 KG Nov 20, 2023
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