Wholesale Price of best 4-Chlorophenyl)acetonitrile CAS NO (140-53-4) in Bulk

1. Introduction to (4-Chlorophenyl)acetonitrile (CAS number 140-53-4): (4-Chlorophenyl)acetonitrile is an organic compound characterized by a phenyl ring substituted with a chloro group (-Cl) at the 4-position and an acetonitrile group (-CN) attached to the phenyl ring. With the CAS number 140-53-4, it finds applications in organic synthesis and chemical intermediates.

2. Chemical Structure and Composition: At its molecular level, (4-Chlorophenyl)acetonitrile features a phenyl ring bearing a chlorine atom and an acetonitrile group attached to the phenyl ring. This structural motif imparts unique reactivity and functional properties to the compound, making it valuable in various synthetic transformations.

3. Synthesis and Production: (4-Chlorophenyl)acetonitrile can be synthesized through several routes, including the reaction of 4-chlorobenzaldehyde with hydroxylamine hydrochloride followed by dehydration, or the cyanation of 4-chlorobenzyl chloride using sodium cyanide or potassium cyanide.

4. Physicochemical Properties: In its pure form, (4-Chlorophenyl)acetonitrile typically appears as a colorless to pale-yellow solid with a characteristic odor. It possesses a moderate melting point and limited solubility in water, making it suitable for organic solvent-based reactions.

5. Applications in Organic Synthesis: (4-Chlorophenyl)acetonitrile serves as a versatile building block in organic synthesis, particularly in the preparation of pharmaceutical intermediates, agrochemicals, and specialty chemicals. Its chloro and cyano groups can undergo various functional group transformations to yield diverse products.

6. Pharmaceutical Intermediates: The unique structural features of (4-Chlorophenyl)acetonitrile make it valuable in the synthesis of pharmaceutical intermediates, including active pharmaceutical ingredients (APIs) and drug candidates. It may serve as a precursor in the synthesis of compounds with biological activity or therapeutic potential.

7. Agrochemicals and Specialty Chemicals: In the agrochemical industry, (4-Chlorophenyl)acetonitrile finds applications in the synthesis of herbicides, insecticides, and fungicides. Its structural versatility allows for the introduction of specific functional groups to tailor the properties and activities of the final products.

8. Safety Considerations and Handling Precautions: As with handling any chemical compound, proper safety precautions should be observed when working with (4-Chlorophenyl)acetonitrile. This includes the use of appropriate personal protective equipment, adherence to safe handling practices, and disposal according to regulatory guidelines.

9. Regulatory Compliance and Environmental Impact: (4-Chlorophenyl)acetonitrile and its derivatives may be subject to regulatory oversight, depending on their intended use and environmental impact. Compliance with regulations governing chemical handling, transportation, and disposal is essential to mitigate potential risks to human health and the environment.

10. Future Perspectives and Emerging Trends: As research into organic synthesis methodologies and chemical intermediates continues to advance, (4-Chlorophenyl)acetonitrile and its derivatives are poised to play a significant role in the development of new materials, pharmaceuticals, and agrochemicals. Future trends may focus on sustainable synthesis methodologies and applications in emerging technologies.