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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Nicotinamide for Sale > White crystalline powder crystalline Crystal Nicotinamide Powder Nicotinamidum Vitamin B3 CAS 98-92-0
White crystalline powder crystalline Crystal Nicotinamide Powder Nicotinamidum Vitamin B3 CAS 98-92-0 buy - large image1
White crystalline powder crystalline Crystal Nicotinamide Powder Nicotinamidum Vitamin B3 CAS 98-92-0 buy - image1
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White crystalline powder crystalline Crystal Nicotinamide Powder Nicotinamidum Vitamin B3 CAS 98-92-0

90 Inquiries

Unit Price: Get Latest Price
CAS No.:

98-92-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

ANY PORT IN CHINA

Brand:

EAST CHEMSORUCES LIMITED

Packaging:

25kg/drum

Price valid (until):

2024-08-01

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Food additives,Pharmaceutical raw materials,Chemicals,Comestic raw materials

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Shop niacinamide Vitamin B3 cosmetics grade anti-wrinkle-Detailed Image 1

    SAFETY DATA SHEETS

    According to the UN GHS revision 9

    Version: 1.0

    Creation Date: July 15, 2019

    Revision Date: July 15, 2019

    SECTION 1: Identification

    1.1GHS Product identifier

    Product name

    Nicotinamide

    1.2Other means of identification

    Product number

    -

    Other names

    3-Pyridinecarboxamide

    1.3Recommended use of the chemical and restrictions on use

    Identified uses

    Industrial and scientific research use.

    Uses advised against

    no data available


    SECTION 2: Hazard identification

    2.1Classification of the substance or mixture

    Eye irritation, Category 2

    2.2GHS label elements, including precautionary statements

    Pictogram(s) Shop niacinamide Vitamin B3 cosmetics grade anti-wrinkle-Detailed Image 2
    Signal word

    Warning

    Hazard statement(s)

    H319 Causes serious eye irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    Storage

    none

    Disposal

    none

    2.3Other hazards which do not result in classification

    no data available

    SECTION 3: Composition/information on ingredients

    3.1Substances

    Chemical name Common names and synonyms CAS number EC number Concentration
    Nicotinamide Nicotinamide 98-92-0 202-713-4 100%

    SECTION 4: First-aid measures

    4.1Description of necessary first-aid measures

    If inhaled

    Fresh air, rest.

    Following skin contact

    Rinse skin with plenty of water or shower.

    Following eye contact

    Rinse with plenty of water (remove contact lenses if easily possible).

    Following ingestion

    Rinse mouth. Give one or two glasses of water to drink.

    4.2Most important symptoms/effects, acute and delayed

    no data available

    4.3Indication of immediate medical attention and special treatment needed, if necessary

    Absorption, Distribution and Excretion

    14(C)Niacinamide was incorporated into an oil-in-water (o/w) skin cream and into a 30% (w/w) soap base and applied to the skin of female Colworth Wistar rats. The final concentration of niacinamide in the soap solution was approximately 0.3% (w/v) and was 1% (w/w) in the skin cream. Application of the skin cream and soap paste was made to rat skin at approximately 20 mg/sq cm. The cream was carefully massaged over 10 sq cm of skin for up to 5 min before covering with polythene-lined occlusive protective patches. The rats were placed in metabolism cages for 48 hr during which time all excreta was collected. At 48 hr, the animals were killed and the patch, carcass, and treated area of skin were assayed for 14(C). Up to 32% 14(C) was recovered in excreta and in the carcasses from rats treated with skin cream containing 14(C)Niacinamide and up to 30% from those treated with soap paste.

    SECTION 5: Fire-fighting measures

    5.1Suitable extinguishing media

    This chemical is a noncombustible solid. Use dry chemical, carbon dioxide, water spray, or alcohol foam extinguishers. Poisonous gases are produced in fire. If material of contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Notify local health and fire officials and pollution control agencies. From a secure, explosion-proof location, use water spray to cool exposed containers. If cooling streams are ineffective (venting sound increase in volume and pitch, tank discolors, or shows any signs of deforming), withdraw immediately to a secure position. If employees are expected to fight fires, they must be trained and equipped in OSHA 1910.156.

    5.2Specific hazards arising from the chemical

    Combustible. Gives off irritating or toxic fumes (or gases) in a fire. Finely dispersed particles form explosive mixtures in air.

    5.3Special protective actions for fire-fighters

    Use water spray, foam, powder, carbon dioxide.

    SECTION 6: Accidental release measures

    6.1Personal precautions, protective equipment and emergency procedures

    Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water.

    6.2Environmental precautions

    Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Wash away remainder with plenty of water.

    6.3Methods and materials for containment and cleaning up

    Evacuate persons not wearing protective equipment from area of spill or leak until clean up is complete. Remove all ignition sources. Use HEPA vacuum or wet method to reduce dust during cleanup. Do not dry sweep. Collect powdered material in the most convenient and safe manner and deposit in sealed containers. Ventilate after clean up is complete. It may be necessary to contain and dispose of this chemical as a hazardous waste. If material of contaminated runoff enters waterways, notify downstream users of potentially contaminated waters. Contact your Department of Environmental Protection or regional office of the federal EPA for specific recommendations. If employees are expected to clean up spills, they must be trained and equipped. OSHA 1910.120 may be applicable.

    SECTION 7: Handling and storage

    7.1Precautions for safe handling

    Prevent deposition of dust. Closed system, dust explosion-proof electrical equipment and lighting. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    7.2Conditions for safe storage, including any incompatibilities

    Separated from oxidants.

    SECTION 8: Exposure controls/personal protection

    8.1Control parameters

    Occupational Exposure limit values

    Component Nicotinamide
    CAS No. 98-92-0

    Limit value - Eight hours Limit value - Short term

    ppm mg/m3 ppm mg/m3
    Latvia
    1


    Remarks

    Biological limit values

    no data available

    8.2Appropriate engineering controls

    Ensure adequate ventilation. Handle in accordance with good industrial hygiene and safety practice. Set up emergency exits and the risk-elimination area.

    8.3Individual protection measures, such as personal protective equipment (PPE)

    Eye/face protection

    Wear safety goggles.

    Skin protection

    Protective gloves.

    Respiratory protection

    Avoid inhalation of dust.

    Thermal hazards

    no data available

    SECTION 9: Physical and chemical properties and safety characteristics

    Physical state

    Solid. Powder.

    Colour

    White.

    Odour

    ODORLESS

    Melting point/freezing point

    130 °C.

    Boiling point or initial boiling point and boiling range

    157 °C. Atm. press.:-0.001 mm Hg.

    Flammability

    Combustible. Gives off irritating or toxic fumes (or gases) in a fire.

    Lower and upper explosion limit/flammability limit

    no data available

    Flash point

    150°C

    Auto-ignition temperature

    Remarks:No self-heating observed up to melting point temperature of ca. 140 °C.

    Decomposition temperature

    no data available

    pH

    10% "wt in vol" soln in water is neutral to litmus

    Kinematic viscosity

    no data available

    Solubility

    2.8 [ug/mL]

    Partition coefficient n-octanol/water

    log Pow = -0.38. Temperature:21 °C. Remarks:No data on pH value.;Pow = 0.421. Temperature:21 °C. Remarks:No data on pH value.

    Vapour pressure

    0 Pa. Temperature:25 °C.

    Density and/or relative density

    1.4 g/cm³. Temperature:25 °C.

    Relative vapour density

    (air = 1): 4.2

    Particle characteristics

    no data available

    SECTION 10: Stability and reactivity

    10.1Reactivity

    On combustion, forms toxic gases including nitrogen oxides. Reacts with oxidants oxidants.

    10.2Chemical stability

    Stable to heat, acids and alkali.

    10.3Possibility of hazardous reactions

    Dust explosion possible if in powder or granular form, mixed with air.An amine and amide. Acts as a weak base in solution. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

    10.4Conditions to avoid

    no data available

    10.5Incompatible materials

    no data available

    10.6Hazardous decomposition products

    When heated to decomposition it emits toxic fumes of nitrogen oxides.

    SECTION 11: Toxicological information

    Acute toxicity

    • Oral: LD50 - rat (male/female) - > 2 500 mg/kg bw.
    • Inhalation: LC50 - rat (male/female) - > 3.8 mg/L air (analytical).
    • Dermal: LD50 - rabbit (male/female) - > 2 000 mg/kg bw.

    Skin corrosion/irritation

    no data available

    Serious eye damage/irritation

    no data available

    Respiratory or skin sensitization

    no data available

    Germ cell mutagenicity

    no data available

    Carcinogenicity

    no data available

    Reproductive toxicity

    no data available

    STOT-single exposure

    The substance is irritating to the eyes.

    STOT-repeated exposure

    no data available

    Aspiration hazard

    A nuisance-causing concentration of airborne particles can be reached quickly when dispersed, especially if powdered.

    SECTION 12: Ecological information

    12.1Toxicity

    • Toxicity to fish: LC50 - Poecilia reticulata - > 1 000 mg/L - 96 h.
    • Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna - > 1 000 mg/L - 24 h.
    • Toxicity to algae: IC50 - Desmodesmus subspicatus (previous name: Scenedesmus subspicatus) - > 1 000 mg/L - 72 h.
    • Toxicity to microorganisms: NOEC - Pseudomonas putida - 4 235 mg/L - 18 h.

    12.2Persistence and degradability

    AEROBIC: Nicotinamide was determined to be readily biodegradable in an aerobic screening test recommended by the Department of Environment, Standing Committee of Analysts, UK(1).

    12.3Bioaccumulative potential

    An estimated BCF of 3 was calculated in fish for nicotinamide(SRC), using a log Kow of -0.37(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

    12.4Mobility in soil

    The Koc of nicotinamide is estimated as 15(SRC), using a log Kow of -0.37(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that nicotinamide is expected to have very high mobility in soil.

    12.5Other adverse effects

    no data available

    SECTION 13: Disposal considerations

    13.1Disposal methods

    Product

    The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

    Contaminated packaging

    Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

    SECTION 14: Transport information

    14.1UN Number

    ADR/RID: Not dangerous goods. (For reference only, please check.) IMDG: Not dangerous goods. (For reference only, please check.) IATA: Not dangerous goods. (For reference only, please check.)

    14.2UN Proper Shipping Name

    ADR/RID: Not dangerous goods. (For reference only, please check.) IMDG: Not dangerous goods. (For reference only, please check.) IATA: Not dangerous goods. (For reference only, please check.)

    14.3Transport hazard class(es)

    ADR/RID: Not dangerous goods. (For reference only, please check.) IMDG: Not dangerous goods. (For reference only, please check.) IATA: Not dangerous goods. (For reference only, please check.)

    14.4Packing group, if applicable

    ADR/RID: Not dangerous goods. (For reference only, please check.) IMDG: Not dangerous goods. (For reference only, please check.) IATA: Not dangerous goods. (For reference only, please check.)

    14.5Environmental hazards

    ADR/RID: No IMDG: No IATA: No

    14.6Special precautions for user

    no data available

    14.7Transport in bulk according to IMO instruments

    no data available

    SECTION 15: Regulatory information

    15.1Safety, health and environmental regulations specific for the product in question

    Chemical name Common names and synonyms CAS number EC number
    Nicotinamide Nicotinamide 98-92-0 202-713-4
    European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
    EC Inventory Listed.
    United States Toxic Substances Control Act (TSCA) Inventory Listed.
    China Catalog of Hazardous chemicals 2015 Not Listed.
    New Zealand Inventory of Chemicals (NZIoC) Listed.
    Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
    Vietnam National Chemical Inventory Listed.
    Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.
    Korea Existing Chemicals List (KECL) Listed.

    SECTION 16: Other information

    Information on revision

    Creation Date July 15, 2019
    Revision Date July 15, 2019

    Abbreviations and acronyms

    • CAS: Chemical Abstracts Service
    • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
    • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
    • IMDG: International Maritime Dangerous Goods
    • IATA: International Air Transportation Association
    • TWA: Time Weighted Average
    • STEL: Short term exposure limit
    • LC50: Lethal Concentration 50%
    • LD50: Lethal Dose 50%
    • EC50: Effective Concentration 50%

    Pls input...

    Shop niacinamide Vitamin B3 cosmetics grade anti-wrinkle-Detailed Image 3

    Items Specifications
    Appearance White crystalline powder, crystalline acicular crystal
    Melting range 128-131
    Assay 98.5-101.5%

    Shop niacinamide Vitamin B3 cosmetics grade anti-wrinkle-Detailed Image 4 Shop niacinamide Vitamin B3 cosmetics grade anti-wrinkle-Detailed Image 5 Shop niacinamide Vitamin B3 cosmetics grade anti-wrinkle-Detailed Image 6 Shop niacinamide Vitamin B3 cosmetics grade anti-wrinkle-Detailed Image 7

    Basic Info
    Product Name:

    Nicotinamide

    Other Name:

    3-Pyridinecarboxamide;Nicotinamide;Aminicotin;Benicot;Delonin Amide;Dipegyl;NAM;Niacinamide;Nicamindon;Nicofort;Nicotilamide;Nicotine acid amide;Nicotinic acid amide;Nicotinic amide;Nicotylamide;Niocinamide;Niozymin;Pelonin amide;3-Pyridinecarboxylic acid amide;Vi-Nicotyl;Vitamin B3 (niacinamide);Vitamin B;Nicosan 2;3-Carbamoylpyridine;Pelmine;β-Pyridinecarboxamide;Nicobion;Nicosylamide;Nicovit;Niavit PP;Nicovitina;Nicamina;Nicasir;3-(Aminocarbonyl)pyridine;m-(Aminocarbonyl)pyridine;3-Amidopyridine;Papulex;Nictoamide;Pelmin;NSC 13128;NSC 27452;Vitamin B3 (nicotinamide);123574-63-0;37321-14-5;78731-47-2

    CAS No.:

    98-92-0

    Molecular Formula:

    C6H6N2O

    InChIKeys:

    InChIKey=DFPAKSUCGFBDDF-UHFFFAOYSA-N

    Molecular Weight:

    122.12500

    Exact Mass:

    122.12

    EC Number:

    202-713-4

    UNII:

    25X51I8RD4

    DEA Code Number:

    1405

    ICSC Number:

    1703

    NSC Number:

    759115|27452|13128

    DSSTox ID:

    DTXSID2020929

    NCI Thesaurus Code:

    C2327

    Color/Form:

    White, powder, needles from benzene|Colorless crystalline solid|White, crystalline powder|Colorless needles

    ATC Code:

    A11HA01|A - Alimentary tract and metabolism

    HScode:

    2933399090

    Characteristics
    PSA:

    55.98000

    XLogP3:

    0.88080

    Appearance:

    Nicotinamide is a white powder. (NTP, 1992)

    Density:

    1.400 g/cm3 @ Temp: 25 °C

    Melting Point:

    130 °C

    Boiling Point:

    157 °C @ Press: 5 x 10-4 Torr

    Flash Point:

    182°C

    Refractive Index:

    1.4660 (estimate)

    Water Solubility:

    1000 g/L (20 ºC)

    Storage Conditions:

    Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

    Vapor Pressure:

    Vapour pressure, kPa at 35°C: 3.1

    Vapor Density:

    Relative vapour density (air = 1): 4.2

    Toxicity:

    LD50 s.c. in rats: 1.68 g/kg (Brazda, Coulson)

    Odor:

    Odorless

    Taste:

    Bitter taste

    PH:

    10% "wt in vol" solution in water is neutral to litmus

    PKA:

    3.35(at 20 °C)

    Henrys Law Constant:

    Henry's Law constant = 2.90X10-12 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    3.35 (at 20 °C)|pKa = 3.35 (conjugate acid)|kb1 = 2.24X10-11; kb2 = 3.16X10-14

    Collision Cross Section:

    125.3 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|129.32 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|137.3 Ų [M+Na]+ [CCS Type: DT, Method: stepped-field]|118 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|125.3 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|121.7 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|125.2 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated]|126.7 Ų [M+H]+

    Experimental Properties:

    Readily hydrolyzed to free acid by heating in acid or alkaline solution|Forms crystalline salts with acids|Hydroxyl radical reaction rate constant = 2.34X10-12 cu cm/molec sec at 25 °C (est)

    Air and Water Reactions:

    Water soluble.

    Reactive Group:

    Amides and Imides

    Reactivity Profile:

    An amine and amide. Acts as a weak base in solution. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

    Autoignition Temperature:

    480 °C

    Physical Dangers:

    Dust explosion possible if in powder or granular form, mixed with air.

    Hazard Identification

    Classification of the substance or mixture

    Eye irritation, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H319 Causes serious eye irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Prevent deposition of dust. Closed system, dust explosion-proof electrical equipment and lighting. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Separated from oxidants.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Food additives,Pharmaceutical raw materials,Chemicals,Comestic raw materials

    Location:

    Room 501, Unit 6, No. 40, hushan road,Licang,Qingdao

    Payment Terms:

    TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    11-50

    Year of Establishment:

    2017

    QINGDAO EASTCHEMSORCES TRADE LIMITED is a leading Manufactory supplier of Sorbitol, Citric acid, Sodium hypochlorite based in Qingdao, Shandong, China. With a commitment to quality and customer satisfaction, QINGDAO EASTCHEMSORCES TRADE LIMITED has become a trusted name in the industry. Our product line includes a range of high-quality Sorbitol, Citric acid, Sodium hypochlorite, which are available at competitive prices. QINGDAO EASTCHEMSORCES TRADE LIMITED has established itself as a reliable supplier of chemical products on the echemi.com.

  • Inquiry History
    90 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Competitive Price CAS 98-92-0 Vitamin B3 Niacinamide 99% white powder 98-92-0

    100 KG Sep 23, 2023
    India

    Nicotinamide   

    45.00 KG Jun 13, 2025
    India

    Nicotinamide  

    25.00 KG Jun 12, 2025
    India

    Nicotinamide

    50.00 KG Jun 11, 2025
    India

    Nicotinamide 

    50.00 KG Jun 13, 2025
    United States

    Niacinamide

    1 KG Feb 5, 2024
    India

    Nicotinamide 

    25.00 KG Jun 11, 2025
    Russia

    Niacinamide

    1 KG Dec 2, 2024
    Pakistan

    Niacinamide

    10.00 MT Jul 10, 2026
    India

    Nicotinamide

    1 KG Jul 1, 2026
    South Korea

    Niacinamide

    150 KG Jun 29, 2026
    India

    Niacinamide

    1.00 MT Jun 26, 2026
    Nigeria

    Niacinamide

    100.00 KG Jun 22, 2026
    India

    Niacinamide

    1.00 KG Jun 1, 2026
    Nigeria

    Niacinamide

    100.00 KG May 25, 2026
    United States

    Nicotinamide

    20 MG May 25, 2026
    India

    Nicotinamide

    500 KG Apr 28, 2026
    India

    Niacinamide

    100.00 KG Apr 13, 2026
    Pakistan

    NICOTINAMIDE

    375 KG Apr 10, 2026
    India

    Niacinamide

    1.00 KG Apr 10, 2026
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