Factory Direct Supply High Quality TNJONE 99% Purity Cyclosporin A 59865-13-3

Cyclosporine is a potent immunosuppressive agent that in animals prolongs survival of allogeneic transplants involving skin, kidney, liver, heart, pancreas, bone marrow, small intestine, and lung. Cyclosporine has been demonstrated to suppress some humoral immunity and to a greater extent, cell-mediated immune reactions such as allograft rejection, delayed hypersensitivity, experimental allergic encephalomyelitis, Freund's adjuvant arthritis, and graft versus host disease in many animal species for a variety of organs.

Applications:

• Cyclosporine initially isolated from the fungus Tolypocladium inflatum isolated from a soil, ciclosporine is a cyclicnonribosomal peptide of 11 amino acids and contains a single D-amino acid, which are rarely encountered in nature.
  Cyclosporine widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection.
  It is often used for the prevention of rejection of a variety of tissues and organs transplantation and the treatment of some immune diseases, and is also used for kidney disease, aplastic anemia, and refractory ulcerative colitis. In dermatology, it is used for stubborn and refractory skin diseases, and the best curative effect is severe psoriasis (including vulgaris, pustular, erythroderma and joint disease). Skin diseases with good curative effect include behcet's disease, pyoderma gangrenosa, lichen planus, epidermolysis bullosa acquired, etc. Diseases with moderate efficacy are alopecia generalis, atopic dermatitis, chronic photolinear dermatitis, photolinear chemicalbook-like reticulocytosis, adult linear IgA bullous dermatitis, pemphigus, and bullous pemphigoid (the latter two require glucocorticoids). In addition, Cyclosporin is also effective for systemic lupus erythematosus, dermatomyositis, systemic scleroderma, AIDS, ichthyosis, cutaneous T-cell lymphoma, rufuropityriasis pilaris, generalized acrodermatitis, palmatoplantar impetigo, male pattern alopecia, vitiligo, progressive necrosis xanthogranuloma, generalized cyclic granuloma, myxedema lichen, papular mucinosis, hyperthyroidism, etc.
  

Shaanxi TNJONE Pharmaceutical Co., Ltd is a high-tech enterprise mainly engaged inthe development and sale of pharmaceutical chemical raw materials and relatedproducts.The company has advanced and perfect supporting system,forming advancedchemical synthesis technology, which can quickly meet the individual needs and serialdevelopment from suitable detection to industrial production.Qur business covers morethan 30 countries, most of customers from Europe, Southeast Asia and other countriesin the world, we can guarantee the quality and price. Our enterprise purpose is basedon the market, strengthen strength, take the road of scientific environmental protectionand sustainable development, rely on the country. The company has a strong financialstrength and a good business environment, can provide customers with quality,efficientand fast service.

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