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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > Thiamphenicol for Sale > Factory Supply Veterinary Medicine CAS 15318-45-3 Thiamphenicol Powder
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Factory Supply Veterinary Medicine CAS 15318-45-3 Thiamphenicol Powder

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Unit Price:

$20-25/KG FOB

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CAS No.:

15318-45-3

Grade:

Pesticide Grade

Content:

99%

Port:

China Port

Brand:

TNJONE

Packaging:

1kg,25kgor according to customer's detail requirement

Price valid (until):

2028-02-01

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Semaglutide,Tirzepatide,API,Vitamins,Food Additive

  • Product Description

  • Seller Information

  • Description


      Product Detail 




    Product Description 

    What is Thiamphenicol ?

    Thiamphenicol (also known as thiophenicol and dextrosulphenidol) is an antibiotic. It is the methyl-sulfonyl analogue of chloramphenicol and has a similar spectrum of activity, but is 2.5 to 5 times as potent. Like chloramphenicol, it is insoluble in water, but highly soluble in lipids. It is used in many countries as a veterinary antibiotic, but is available in China, Morocco and Italy for use in humans. Its main advantage over chloramphenicol is that it has never been associated with aplastic anaemia.



    Thiamphenicol is a chloramphenicol broad-spectrum antibiotic, which is more effective against gram-negative bacteria than positive bacteria. At room temperature, it is white to white crystalline powder or crystal, which can be absorbed quickly and completely by oral administration. In terms of metabolism, it is mainly excreted from urine in its original form. Clinically, it is mainly used for the treatment of respiratory, urinary, hepatobiliary, typhoid and other intestinal surgery, obstetrics and gynecology and ent infection, especially for mild infection.

    Function

    Thiamphenicol a class of broad-spectrum antibiotic chloramphenicol, against Gram-positive bacteria, such as the lung bacteria,hemolytic streptococcus strong antibacterial action on Gram-positive bacteria such as gonorrhea,meningitis Meningitis, lung Bacteroides, E. coli, Vibrio cholerae, Shigella, and influenza bacillus have a strong antibacterial effect on anaerobic bacteria family, Rickettsia, amoeba, also has some antibacterial action.
    Thiamphenicol is mainly used for respiratory, urinary, liver and gallbladder, typhoid and other intestinal surgery, gynecology and ENT infections embolism, especially the role of mild infections in particular. thiamphenicol also has strong immunosuppressive effects , is an excellent immunosuppressant.
    Thiamphenicol is applied for the treatment of respiratory, urinary tract, liver and gallbladder, typhoid and other intestinal surgery, gynecology and ENT infections. Especially in the mild infections it is more effective


    Thiamphenicol Chemical Properties
    Melting point  163-166 °C
    alpha  D25 +12.9° (ethanol)
    density  1.3281 (rough estimate)
    refractive index  1.6000 (estimate)
    storage temp.  Sealed in dry,Room Temperature
    solubility  ethanol: 50 mg/mL, clear, colorless
    Boiling point  695.9±55.0 °C(Predicted)
    pKa 11.05±0.46(Predicted)
    form  powder
    color  white to off-white
    Water Solubility  Soluble in acetonitrile or DMF. Slightly soluble in water
    Merck  14,9301
    BRN  2819542
    InChIKey OTVAEFIXJLOWRX-NXEZZACHSA-N
    CAS DataBase Reference 15318-45-3
    EPA Substance Registry System Thiamphenicol (15318-45-3)
    Items Specifications
    Product Name Thiamphenicol
    Cas No 15318-45-3
    Einecs 239-355-3
    MF C12H15Cl2NO5S
    MW 356.22
    Melting Point 163-166 °C
    Density 1.3281 (rough estimate)
    Appearance White crystalline powder
    Shelf Life 2 Years When Properly Stored
    Storage Keep in a cool, dry, dark location in a tightly sealed container or cylinder.


    Application

    An antibiotic produced by the soil actinomycete Streptomyces griseus. It acts by inhibiting the initiation and elongation processes during protein synthesis.
    For tularemia, plague, brucellosis and glanders serious treatment (often combined with tetracycline or chloramphenicol). Also used second-line treatment of TB and multi-combination with other anti-TB drugs.
    Thiamphenicol is also widely used in Brazil, particularly for the treatment of sexually transmitted infections and pelvic inflammatory disease.Unlike chloramphenicol, thiamphenicol is not readily metabolized in cattle, poultry, sheep, or humans, but is predominantly excreted unchanged. In pigs and rats the drug is excreted both as parent drug and as thiamphenicol glucuronate (FAO,1997).










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    Certificates
    • Factory Supply Veterinary Medicine CAS 15318-45-3 Thiamphenicol Powder Certificates 1

    Basic Info
    Product Name:

    Thiamphenicol

    Other Name:

    Acetamide,2,2-dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-;Acetamide,2,2-dichloro-N-[β-hydroxy-α-(hydroxymethyl)-p-(methylsulfonyl)phenethyl]-,D-threo-(+)-;Acetamide,2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]-,[R-(R*,R*)]-;2,2-Dichloro-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl]acetamide;(Methylsulfonyl)chloramphenicol;8065CB;Win 5063-2;Dextrosulphenidol;D-d-threo-2-Dichloroacetamido-1-(4-methylsulfonylphenyl)-1,3-propanediol;Thiamphenicol;D-Thiocymetin;D-Thiophenicol;Thiocymetin;Thiophenicol;D-threo-(1R,2R)-1-(p-Methylsulfonylphenyl)-2-dichloroacetamido-1,3-propanediol;(+)-Thiamphenicol;NSC 522822;Tirsan;(2′R,3′R)-Thiamphenicol;90-91-5;3785-14-6;14786-51-7;32430-04-9

    CAS No.:

    15318-45-3

    Molecular Formula:

    C12H15Cl2NO5S

    InChIKeys:

    InChIKey=OTVAEFIXJLOWRX-NXEZZACHSA-N

    Molecular Weight:

    356.22200

    Exact Mass:

    356.22

    EC Number:

    239-355-3

    UNII:

    FLQ7571NPM

    NSC Number:

    758396

    DSSTox ID:

    DTXSID5021338

    ATC Code:

    J01BA02|J - Antiinfectives for systemic use

    HScode:

    2941400000

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    112.08000

    XLogP3:

    -0.3

    Appearance:

    off-white solid

    Density:

    1.55 g/cm3

    Melting Point:

    165.3 °C

    Boiling Point:

    695.9ºC at 760mmHg

    Flash Point:

    374.7ºC

    Refractive Index:

    1.589

    Water Solubility:

    ethanol: 50 mg/mL, clear, colorless

    Collision Cross Section:

    170.7 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|179.09 Ų [M-H]-

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Semaglutide,Tirzepatide,API,Vitamins,Food Additive

    Location:

    No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New City, Xi 'an, Shaanxi Province

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    5

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2019

    Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital Xi 'an, is committed to the peptide industry, pharmaceutical raw materials, food and feed additives, veterinary drugs and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products, "world peace and health" as its responsibility, the company adhering to the "meet all customer requirements for products" as the service concept, Guarantee "provide qualified products" as the service principle, so that you get "God-like" noble shopping enjoyment. Our company has more than 1000 kinds of polypeptides, raw materials inventory, at any time to meet the various needs of customers for products. Is your best partner.
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