Daunorubicin Hydrochloride CAS 23541-50-6 Daunorubicin HCl

Daunorubicin Hydrochloride CAS 23541-50-6 Daunorubicin HCl

What is Daunorubicin Hydrochloride/Daunorubicin HCl ?

Doxorubicin Hydrochloride is the hydrochloride salt of doxorubicin, an anthracycline antibiotic with antineoplastic activity.   Doxorubicin, isolated from the bacterium Streptomyces peucetius var. caesius, is the hydroxylated congener of daunorubicin.   Doxorubicin intercalates between base pairs in the DNA helix, thereby preventing DNA replication and ultimately inhibiting protein synthesis.   Additionally, doxorubicin inhibits topoisomerase II which results in an increased and stabilized cleavable enzyme-DNA linked complex during DNA replication and subsequently prevents the ligation of the nucleotide strand after double-strand breakage.   Doxorubicin also forms oxygen free radicals resulting in cytotoxicity secondary to lipid peroxidation of cell membrane lipids;   the formation of oxygen free radicals also contributes to the toxicity of the anthracycline antibiotics, namely the cardiac and cutaneous vascular effects.

Specification 

Application

1) this product can only be used for intravenous injection, because of venous irritation, can cause thrombophlebitis, it should not drip. If redness, pain or spills, immediately stop and take appropriate measures, such as a cold compress.
2)can not be performed during the FDA radiotherapy, especially thoracic radiotherapy. Disable least 3-4 weeks after radiotherapy to apply daunorubicin.
3) during the treatment and should be monitored before each chemotherapy, blood and heart function, regular liver and kidney function tests.
4)the product in animals can cause reproductive dysfunction and obstacles delayed. In male dogs can cause testicular atrophy.

Company Information 

Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital of Xi 'an, is committed to pharmaceutical raw materials, kill varieties, food and feed additives, chemical reagents, plant extracts and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products. Our company after careful planning, hard study, gradually formed a complete service system, based on the domestic and foreign raw materials market special development. Make the raw materials industry bigger and stronger, and serve the vast number of new and old customers. With "world peace and health" as its responsibility, the company adheres to the service concept of "meeting all requirements of customers for products", and guarantees the service principle of "providing qualified products", so that you can get the "God-like" noble shopping enjoyment. Our company has more than 500 kinds of raw materials inventory at any time to meet the various needs of customers for products. The company's products all comply with the relevant national regulations, from the smallest packaging to tons of goods are available. Is your choice of raw materials the best partner.

Shaanxi TNJONE Pharmaceutical Technology Co., Ltd. is willing to rely on the rapid development of e-commerce and national policy support of the good environment background, nesting, welcome people from all walks of life to visit our company, exchange, and seek common development, looking forward to sharing with you, win-win, to realize the dream.

FAQ

1.How to get in touch with us?

You can chat with us by Trademanager,WhatsApp or simply giving us an email, a phone call. All our contacts information can be found from our website.

2.Are you a manufacturer or trade company?

We are a professional manufacturer.

3.Can I get a sample?

Yes, free sample can be provided, but shipping cost is covered by your side.

4.What's your MOQ?

It is based on the different product. Some are 1g while some are 1 kg. Please be free to consult our salesman.

5.When can I get the quotation?
We usually quote within 1 hours after we get your inquiry. If it's a urgent order you can call us or mention it in your email subject, and we can take it as priority.

6.Is there any discount?
Yes, some products are applied for discount, but it depends on the quantity.

7.Can you do OEM for me?
Yes,we accept OEM orders, just contact us and give us your requirement. We will offer you a reasonable price and make samples ASAP.