L-5-Methyltetrahydrofolate Calcium/L-5-Mthf-Ca /6s-5-Methyltetrahydrofolate Calcium CAS151533-22-1 Calcium Levomefolate

Certification

Function  

L-5-Methyltetrahydrofolate calcium(L-5-MTHF-Ca) is also known as calcium levomefolate; N-[4-[[(2-amino-1,4,5,6,7,8-hexahydro-5-methyl-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid, calcium salt; and L-5-MTHF.
L-5-Methyltetrahydrofolate calcium(L-5-MTHF-Ca) is the calcium salt of L-5-methyltetrahydrofolic acid, and a member of the folate group of vitamins (Vitamin B9). It is the coenzymated and most active form of folic acid, which performs many vital cellular functions, including DNA reproduction, cysteine cycle and homocysteine regulation.
L-5-Methyltetrahydrofolate calcium(L-5-MTHF-Ca) is used as in dietary supplements and has been proposed for treatment of cardiovascular disease.

Application

1. L-5-MTHF Ca is Mainly for folic acid antagonists (such as methotrexate, pyrimethamine, benzyl cefalexin and trimethoprim) antidote, it's usually used for prevention of methotrexate dose or overdosetreatment caused severe toxic effects.

2. L-5-MTHF Ca is used for Folic acid treatment of the following diseases, such as inflammatory diarrhea and protein-energy malnutrition (poor nutrition), pregnancy or infancy megaloblastic anemia caused b poor.

3. L-5-MTHF Ca as adjuvant therapy for colon cancer, rectal cancer.

4. Combined with 5-FU and treatment of digestive tract tumors or other 5-FU-sensitive tumors.High-dose CF used in conjunction with 5-FU (LF), the basic programme is currently the treatment of colon and rectal cancer.

5. L-5-MTHF Ca is used For children with leukemia, lymphoma, and osteosarcoma, such as high dose MTX treatment when rescued.