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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > Docetaxel for Sale > Hot Selling API Pharmaceutical Raw Material Docetaxel Powder CAS 114977-28-5
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Hot Selling API Pharmaceutical Raw Material Docetaxel Powder CAS 114977-28-5

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Unit Price: Get Latest Price
CAS No.:

114977-28-5

Grade:

Pharmaceutical Grade

Content:

98%

Port:

china any port

Brand:

TNJONE

Packaging:

1kg ,25kg or according to customer's detail requirement.

Price valid (until):

2025-12-30

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Semaglutide,Tirzepatide,API,Vitamins,Food Additive

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Hot Selling API Pharmaceutical Raw Material Docetaxel Powder CAS 114977-28-5

    What  is Docetaxel ?

    Docetaxel is a clinically well established anti-mitotic chemotherapy medication used mainly for the treatment of breast, ovarian, and non-small cell lung cancer. Docetaxel has an approved claim for treatment of patients who have locally advanced, or metastatic breast or non small-cell lung cancer who have undergone anthracycline-based chemotherapy and failed to stop cancer progression or relapsed.Administered as a one-hour infusion every three weeks generally over a ten cycle course, docetaxel is considered better than doxorubicin, paclitaxel and fluorouracil as a cytotoxic antimicrotubule agent.

    Items Specifications
    Product Name Docetaxel
    CAS No. 114977-28-5
    Appearance white powder
    Assay 98%
    MF C43H53NO14
    MW 807.88
    Melting Point 186-192 °C (dec.)
    Boiling Point 900.5±65.0 °C(Predicted)
    Density 1.38 g/cm3(Predicted)


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    Certification 

    Technical Date Sheet:


    Analysis
    Specification
    Result
    Test method
    Physical Description



    Appearance
    White Powder
    White Powder
    Visual
    Odor
    Characteristic
    Characteristic
    Organoleptic
    Particle size
    90% pass 80 mesh
    90% pass 80 mesh
    80 Mesh Screen
    Chemical Tests



    Assay (Lutein)
    99%
    90.15%
    HPLC
    Loss on drying
    5.0% Max
    1.82%
    5g/105ºC/2hrs
    Ash Contents
    5.0% Max
    1.12%
    2g/525ºC/3hrs
    Residual Solvents
    50.0 ppm, Only Ethanol
    <30.0 ppm
    /
    Heavy metals
    5.0 ppm Max
    <3.0 ppm
    AAS
    Lead
    3.0 ppm Max
    <1.0 ppm
    AAS
    Arsenic
    3.0 ppm Max
    <1.0 ppm
    AAS
    Microbiology Control



    Total Bacteria Count
    1,000cfu/g Max
    <280cfu/g
    AOAC
    Yeast & Mold
    100cfu/g Max
    <10cfu/g
    AOAC
    Conclusion
    Complies with the standards.


    Function:

    1. Antineoplastic Agent: Docetaxel works by inhibiting cell division, specifically during the mitotic phase, by promoting the assembly of microtubules and preventing their depolymerization. This action disrupts the normal function of microtubules, essential for cell division, thereby inhibiting the growth and spread of cancer cells.

    2. Apoptosis Induction: It induces apoptosis (programmed cell death) in cancer cells by stabilizing microtubule formation, leading to cell cycle arrest and cell death.

    3. Antiangiogenic Properties: Docetaxel exhibits antiangiogenic effects, meaning it can inhibit the formation of new blood vessels that tumors need to grow and metastasize.


    Application:

    1. Oncology:

      • Breast Cancer: Docetaxel is used as a first-line treatment for locally advanced or metastatic breast cancer, either alone or in combination with other chemotherapeutic agents.
      • Non-Small Cell Lung Cancer (NSCLC): It is administered in combination with other drugs for the treatment of NSCLC, particularly in patients who have failed prior platinum-based chemotherapy.
      • Prostate Cancer: Docetaxel, in combination with prednisone, is used for the treatment of metastatic castration-resistant prostate cancer.
      • Gastric Cancer: It is used in combination with other chemotherapeutic agents for the treatment of advanced gastric adenocarcinoma.
      • Head and Neck Cancer: Docetaxel is used in combination with cisplatin and fluorouracil for the treatment of locally advanced squamous cell carcinoma of the head and neck.
    2. Research and Development:

      • Cancer Research: Docetaxel is widely used in preclinical and clinical research to study its mechanisms of action, resistance, and potential new therapeutic combinations.
      • Pharmaceutical Development: It is a key compound in the development of new formulations and delivery systems aimed at improving efficacy and reducing side effects.
    3. Palliative Care:

      • Symptom Management: In advanced stages of cancer, Docetaxel is used to help manage symptoms and improve the quality of life for patients by slowing the progression of the disease.
    4. Combination Therapy:

      • Chemotherapy Regimens: Docetaxel is often used in combination with other chemotherapeutic agents, targeted therapies, and immunotherapies to enhance therapeutic outcomes and overcome drug resistance.
    5. Adjuvant and Neoadjuvant Therapy:

      • Preoperative Treatment: Docetaxel is used in neoadjuvant therapy to shrink tumors before surgical removal.
      • Postoperative Treatment: It is used in adjuvant therapy to eliminate any remaining cancer cells following surgery, reducing the risk of recurrence.

     Company Information 


    Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital of Xi 'an, is committed to pharmaceutical raw materials, kill varieties, food and feed additives, chemical reagents, plant extracts and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products. Our company after careful planning, hard study, gradually formed a complete service system, based on the domestic and foreign raw materials market special development. Make the raw materials industry bigger and stronger, and serve the vast number of new and old customers. With "world peace and health" as its responsibility, the company adheres to the service concept of "meeting all requirements of customers for products", and guarantees the service principle of "providing qualified products", so that you can get the "God-like" noble shopping enjoyment. Our company has more than 500 kinds of raw materials inventory at any time to meet the various needs of customers for products. The company's products all comply with the relevant national regulations, from the smallest packaging to tons of goods are available. Is your choice of raw materials the best partner.


    Shaanxi TNJONE Pharmaceutical Technology Co., Ltd. is willing to rely on the rapid development of e-commerce and national policy support of the good environment background, nesting, welcome people from all walks of life to visit our company, exchange, and seek common development, looking forward to sharing with you, win-win, to realize the dream.


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    FAQ

    1.How to get in touch with us?

    You can chat with us by Trademanager,WhatsApp or simply giving us an email, a phone call. All our contacts information can be found from our website.

     

    2.Are you a manufacturer or trade company?

    We are a professional manufacturer.

     

    3.Can I get a sample?

    Yes, free sample can be provided, but shipping cost is covered by your side.

     

    4.What's your MOQ?

    It is based on the different product. Some are 1g while some are 1 kg. Please be free to consult our salesman.

     

    5.When can I get the quotation?
    We usually quote within 1 hours after we get your inquiry. If it's a urgent order you can call us or mention it in your email subject, and we can take it as priority.

     

    6.Is there any discount?
    Yes, some products are applied for discount, but it depends on the quantity.

     

    7.Can you do OEM for me?
    Yes,we accept OEM orders, just contact us and give us your requirement. We will offer you a reasonable price and make samples ASAP.

    Certificates

    Basic Info
    Product Name:

    Docetaxel

    Other Name:

    Benzenepropanoic acid,β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-,(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester,(αR,βS)-;Benzenepropanoic acid,β-[[(1,1-dimethylethoxy)carbonyl]amino]-α-hydroxy-,12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,6,11-trihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester,[2aR-[2aα,4β,4aβ,6β,9α(αR*,βS*),11α,12α,12aα,12bα]]-;7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete,benzenepropanoic acid deriv.;RP 56976;Docetaxel;Taxotere;N-Debenzoyl-N-tert-butoxycarbonyl-10-deacetyltaxol;Docetaxol;Docetere;Taxotel;SID 530;Duopafei;Docefrez;BIND 014;Miradocetaxel;CKD 810;CRLX 301;ATI 1123;216252-50-5;129522-72-1

    CAS No.:

    114977-28-5

    Molecular Formula:

    C43H53NO14

    InChIKeys:

    InChIKey=ZDZOTLJHXYCWBA-VCVYQWHSSA-N

    Molecular Weight:

    807.87900

    Exact Mass:

    807.88

    EC Number:

    601-339-2

    HScode:

    2932999099

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    224.45000

    XLogP3:

    1.6

    Appearance:

    Off-white Cryst.

    Density:

    1.37 g/cm3

    Melting Point:

    232 °C

    Boiling Point:

    900.5ºC at 760 mmHg

    Flash Point:

    498.4ºC

    Refractive Index:

    1.618

    Water Solubility:

    1.27e-02 g/L

    Storage Conditions:

    Keep tightly closed. Store at +4ºC.

    Vapor Pressure:

    5.61X10-27 mm Hg at 25 deg C (est)

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Semaglutide,Tirzepatide,API,Vitamins,Food Additive

    Location:

    No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New City, Xi 'an, Shaanxi Province

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    5

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2019

    Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital Xi 'an, is committed to the peptide industry, pharmaceutical raw materials, food and feed additives, veterinary drugs and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products, "world peace and health" as its responsibility, the company adhering to the "meet all customer requirements for products" as the service concept, Guarantee "provide qualified products" as the service principle, so that you get "God-like" noble shopping enjoyment. Our company has more than 1000 kinds of polypeptides, raw materials inventory, at any time to meet the various needs of customers for products. Is your best partner.
  • Inquiry History
    3 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Factory Raw Powder Pharmaceutical Docetaxel CAS 114977-28-5 High Purity 99%

    1 KG Oct 20, 2023
    Nigeria

    Docetaxel

    5 G Apr 13, 2026
    Brazil

    Docetaxel

    1.00 KG Mar 29, 2025
    Post an enquiry for this product
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