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Anticancer Pharmaceutical Chemical Powder Double Maleate (BIBW2992) CAS 850140-73-7 Afatinib Dimaleate buy - image1

Anticancer Pharmaceutical Chemical Powder Double Maleate (BIBW2992) CAS 850140-73-7 Afatinib Dimaleate buy - image2

Anticancer Pharmaceutical Chemical Powder Double Maleate (BIBW2992) CAS 850140-73-7 Afatinib Dimaleate buy - image3

Anticancer Pharmaceutical Chemical Powder Double Maleate (BIBW2992) CAS 850140-73-7 Afatinib Dimaleate buy - image4

Anticancer Pharmaceutical Chemical Powder Double Maleate (BIBW2992) CAS 850140-73-7 Afatinib Dimaleate

Name: Anticancer Pharmaceutical Chemical Powder Double Maleate (BIBW2992) CAS 850140-73-7 Afatinib Dimaleate
Brand: TNJONE
SKU: pr2408121314
Price: 69 USD
Availability: InStock

Unit Price: Get Latest Price 

CAS No.:

850140-73-7

Grade:

Afatinib is a new generation of oral small molecule tyrosine kinase inhibitors (TKI), an irreversible ErbB family blocker that acts on the entire ErbBChemicalbook family, including EGFR. Unlike the first generation of reversible EGFRTKI, afatinib binds irreversibly to EGFR, thus shutting down cancer cell signaling pathways and inhibiting tumor growth.

Product Name	Afatinib dimaleate
Appearance	powder
Molecular formula	C28H29ClFN5O7
Keywords	BIBW2992DiMaleate;BIBW2992-MA2;Afatinib(diMaleate);Afatinib(diMaleate),BIBW2992;2-ButenaMide,N-[4-[(3-chloro-4-fluorophenyl)aMino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-Chemicalbook6-quinazolinyl]-4-(diMethylaMino)-,(2E)-,(2Z)-2-butenedioate(1:2);(2E)-N-(4-[(3-chloro-4-fluorophenyl)aMino]-7-{[(3S);AfatinibdoubleMaleate;Afatinib(BIBW2992)Dimaleate
Shelf Life	24 months when properly stored
Storage	Keep in a cool, dry, dark location

Function and Application

1.Afatinib bismaleate is an organic synthesis intermediate and pharmaceutical intermediate, which can be used in laboratory research and development process and chemical pharmaceutical synthesis process.
2.Afatinib bismaleate, a salt of Afatinib (BIBW2992)(B377000), is an amino-toluidine substituted quinazoline derivative Chemicalbook used for the treatment of cancers and diseases of the respiratory tract, lung, gastrointestinal, bile duct and gallbladder. A phenylquinazoline that irreversibly inhibits EGFR and HER2 kinase activity.

Company Profile

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Shaanxi TNJONE Pharmaceutical Co., Ltd is a high-tech enterprise mainly engaged inthe development and sale of pharmaceutical chemical raw materials and relatedproducts.The company has advanced and perfect supporting system,forming advancedchemical synthesis technology, which can quickly meet the individual needs and serialdevelopment from suitable detection to industrial production.Qur business covers morethan 30 countries, most of customers from Europe, Southeast Asia and other countriesin the world, we can guarantee the quality and price. Our enterprise purpose is basedon the market, strengthen strength, take the road of scientific environmental protectionand sustainable development, rely on the country. The company has a strong financialstrength and a good business environment, can provide customers with quality,efficientand fast service.

Our Advantages

Shop GMP TNJONE High Purity Pharmaceutical Raw Materials CAS 38821-53-3 Cephradine-Detailed Image 4
1.High quality and competitive price.
2.Free sample for your evaluation.
3.Promptly delivery by well-reputed shipping lines.
4.Trial order is available for testing after samples.
5.We will inform you all the information at every stage in advance.
6.Packaging can gear to buyers' special request.

Our factory

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Our package

Shop High Purity Pharmaceutical API Antibiotic Raw Material Fusidine Powder CAS 6990-06-3-Detailed Image 10

Shop TNJONE High Quality TNJONE Pharmaceutical Intermediate CAS 376592-93-7 3 -Amino-2 -Hydroxy-Biphenyl-3-Carboxylic Acid-Detailed Image 10

How to order

Before ordering	Please send what items and what quantity you need
Send quotation	We will send you a quotation in detail with total
Payment ways chosen	Please choose one of the payment way you preferred. Our payment ways: City bank,BTC,Bank wire, Wise,Master Card , Tether
After payment	Please offer shipping address after payment for shipment.
Tracking	We will provide the tracking after goods sent.
Lead time	About 1-5 working days after payment
Shipping time	About 8-15 days door to door
After-sale service	Available always

ECHEMI Editorial Reference

Afatinib dimaleate is an irreversible EGFR family inhibitor with IC50s of 0.5 nM, 0.4 nM, 10 nM and 14 nM for EGFRwt, EGFRL858R, EGFRL858R/T790M and HER2, respectively.

Basic Info

Product Name:

Afatinib dimaleate

Other Name:

2-Butenamide,N-[4-[(3-chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4-(dimethylamino)-,(2E)-,(2Z)-2-butenedioate (1:2);Afatinib dimaleate;BIBW 2992MA2;2047333-62-8

CAS No.:

850140-73-7

Molecular Formula:

C24H25ClFN5O3.2C4H4O4

InChIKeys:

USNRYVNRPYXCSP-JUGPPOIOSA-N

Molecular Weight:

718.0827232

Exact Mass:

717.184937

HScode:

29339900

Categories:

Other Chemical Drugs

Characteristics

PSA:

238 Å²

XLogP3:

4.53600

See More Afatinib dimaleate Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H319 Causes serious eye irritation H361 Suspected of damaging fertility or the unborn child H362 May cause harm to breast-fed children H372 Causes damage to organs through prolonged or repeated exposure
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Afatinib dimaleate Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Semaglutide,Tirzepatide,API,Vitamins,Food Additive

Location:
No. 4C-11-A392, Financial Port, Northwest corner of Fengjing Avenue and Fengxin Road, Fengdong New City, Xi 'an, Shaanxi Province

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
5 days

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2019

Shaanxi TNJONE Pharmaceutical Technology Co., LTD., located in the beautiful ancient capital Xi 'an, is committed to the peptide industry, pharmaceutical raw materials, food and feed additives, veterinary drugs and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products, "world peace and health" as its responsibility, the company adhering to the "meet all customer requirements for products" as the service concept, Guarantee "provide qualified products" as the service principle, so that you get "God-like" noble shopping enjoyment. Our company has more than 1000 kinds of polypeptides, raw materials inventory, at any time to meet the various needs of customers for products. Is your best partner.
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More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
Afatinib Dimaleate cas 850140-73-7	Pharmaceutical Grade/99.8	$1000-1222/KG FOB	Chong Da Prostaglandin Fine Chemicals Co., Ltd	Inquiry
Afatinib dimaleate RC09817	Pharmaceutical Grade/99	$1/KG EXW	Hangzhou Royalchem Co.,LTD	Inquiry
BIBW2992 DiMaleate	/99.00		HANGZHOU LEAP CHEM CO., LTD.	Inquiry
Get 99% pure Afatinib dimaleate CAS 850140-73-7 for the best price	Pharmaceutical Grade/99		Xi'an Honest BioEngr Co.,Ltd.	Inquiry
High Quality Afatinib diMaleate CAS 850140-73-7 Powder Fast Shipping Good Price	Pharmaceutical Grade/99.5		Hangzhou Hyper Chemicals Limited	Inquiry

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Anticancer Pharmaceutical Chemical Powder Double Maleate (BIBW2992) CAS 850140-73-7 Afatinib Dimaleate

Product Description

Seller Information