Diphenhydramine hydrochloride CAS: 147-24-0
7 Inquiries
147-24-0
shanghai
25KG
2024-09-21
Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate
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Product Details
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Seller Information
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Inquiry History
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DescriptionECHEMI Editorial ReferenceWhite or almost white, crystalline powder.ChEBI: The hydrochloride salt of diphenhydramine.Diphenhydramine hydrochloride is an antihistamine drug having the chemical name 2-(Diphenylmethoxy)- N,N-dimethylethylamine hydrochloride. It occurs as a white, crystalline powder, is freely soluble in water and alcohol and has a molecular weight of 291.82.
Diphenhydramine hydrochloride appears as white or almost-white crystalline powder. Odorless with a bitter numbing taste. pH (5% aqueous solution) 4-6. (NTP, 1992)
Diphenhydramine hydrochloride appears as white or almost-white crystalline powder. Odorless with a bitter numbing taste. pH (5% aqueous solution) 4-6. (NTP, 1992)|Diphenhydramine Hydrochloride is the hydrochloride salt form of diphenhydramine, an ethanolamine and first-generation histamine antagonist with anti-allergic activity. Diphenhydramine hydrochloride competitively blocks H1receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries, and gastrointestinal (GI) smooth muscle. This prevents histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms.|A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.Basic Info-
Product Name:
Diphenhydramine hydrochloride
Other Name:Ethanamine,2-(diphenylmethoxy)-N,N-dimethyl-,hydrochloride (1:1);Ethylamine,2-(diphenylmethoxy)-N,N-dimethyl-,hydrochloride;Ethanamine,2-(diphenylmethoxy)-N,N-dimethyl-,hydrochloride;Bena;Benadryl;Benzhydramine hydrochloride;2-(Benzhydryloxy)-N,N-dimethylethylamine hydrochloride;β-Dimethylaminoethyl benzhydryl ether hydrochloride;Diphenhydramine hydrochloride;2-Diphenylmethoxy-N,N-dimethylethylamine hydrochloride;Difenhydramine hydrochloride;Denydryl;Dimedrol;Dimedrol hydrochloride;Allergan;Allergival;Benadril hydrochloride;Restamin;Vena;Resmin;Benzhydrol β-dimethylaminoethyl ether hydrochloride;Halbmond;Benocten;Sekundal D;Allergina;Noctomin;Bagodryl;Bena-Fedrin;Amidryl;Alledryl;Fenylhist;Bax;Dibondrin;S 8;Wehydryl;Benylin;Syntedril;Sedopretten;Diphantine;Benodine;Histacyl;Benzantin;Asdrin;Benison;Theraflu;Dimedrolum;Psilo-Balsam;[2-(Diphenylmethoxy)ethyl]dimethylamine hydrochloride;8052-21-9
CAS No.:147-24-0
Molecular Formula:C17H21NO.ClH
InChIKeys:InChIKey=PCHPORCSPXIHLZ-UHFFFAOYSA-N
Molecular Weight:291.81600
Exact Mass:291.13900
EC Number:205-687-2
UNII:TC2D6JAD40
NSC Number:756729|33299
DSSTox ID:DTXSID4020537
NCI Thesaurus Code:C300
HScode:2933990090
Categories:
Characteristics-
PSA:
12.47000
XLogP3:4.15620
Appearance:Diphenhydramine hydrochloride appears as white or almost-white crystalline powder. Odorless with a bitter numbing taste. pH (5% aqueous solution) 4-6. (NTP, 1992)
Density:1.024g/cm3
Melting Point:166-170 °C
Boiling Point:163-167 °C @ Press: 3 Torr
Flash Point:101.5ºC
Refractive Index:1.5800 (estimate)
Water Solubility:H2O: 1000 g/L
Storage Conditions:Keep in a cool, dry, dark location in a tightly sealed container or cylinder. Keep away from incompatible materials, ignition so
Toxicity:LD50 orally in rats: 500 mg/kg (Gruhzit, Fisken)
Collision Cross Section:162.7 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]
Air and Water Reactions:Water soluble. Aqueous solutions are acidic.
Reactive Group:Ethers
Reactivity Profile:DIPHENHYDRAMINE HYDROCHLORIDE gives acidic solutions in water. Neutralizes bases. May react with strong oxidizing and strong reducing agents. May catalyze organic reactions. Slowly darkens on exposure to light.
Hazard IdentificationClassification of the substance or mixture
Acute toxicity - Category 4, Oral
GHS label elements, including precautionary statements
Pictogram(s) 
Signal word Warning
Hazard statement(s) H302 Harmful if swallowed
Precautionary statement(s) Prevention P264 Wash ... thoroughly after handling.
P270 Do not eat, drink or smoke when using this product.
Response P301+P317 IF SWALLOWED: Get medical help.
P330 Rinse mouth.
Storage none
Disposal P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.
Other hazards which do not result in classification
no data available
Handling and StoragePrecautions for safe handling
Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.
Conditions for safe storage, including any incompatibilities
Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.
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Seller Information
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Business Type:
Manufactory
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Main Products:
Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate
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Location:
hisense intelligence valley,no 2116,of phoenix road
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Payment Terms:
TT against copy of documents,D/P,L/C
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Average lead Time:
7 days
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Total Annual Revenue:
Less than $1 million
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Total Employees:
11-50
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Year of Establishment:
2017
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Inquiry History7 Inquiries
Country Product Purchase Quantity Date Posted 
United States
Diphenhydramine Hydrochloride
200 G Feb 12, 2026 
United Kingdom
API Raw Material Diphenhydramine Hydrochloride CAS:147-24-0
1 Jan 10, 2026
United States
DIPHENHYDRAMINE HYDROCHLORIDE
100 G Sep 25, 2025 
Australia
Diphenhydramine hydrochloride
1 KG Dec 2, 2024
United States
Diphenhydramine hydrochloride
100 G May 8, 2026 
Thailand
Diphenhydramine Hydrochloride
1 KG Nov 19, 2024 
Nigeria
Chloropheniramine
200 G Jun 26, 2025 Post an enquiry for this product
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