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D-α-Tocopherol polyethylene glycol 1000 succinate buy - large image1
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D-α-Tocopherol polyethylene glycol 1000 succinate

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Unit Price: Get Latest Price
CAS No.:

9002-96-4

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

Hyper Chem

Packaging:

20kg/Drum 25kg/Drum

Price valid (until):

2024-10-27

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Description

    Name

    D-α-Tocopherol polyethylene glycol 1000 succinate

    CAS number

    9002-96-4

    Synonym

    D –α-Tocopherol PEG 1000 succinate; D-α-Tocopherol polyethylene glycol succinate, TPGS, Vitamin E polyethylene glycol succinate, Vitamin E-TPGS

    Description

    D-Alpha-tocopheryl polyethylene glycol 1000 succinate (Tocofersolan, Vedrop), has been developed in Europe as an orally bioavailable source of vitamin E in children suffering from cholestasis. Cholestasis is the reduction or stoppage of bile flow, either to impaired secretion by hepatocytes (liver cells) or obstruction.

    Tocofersolan is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version of Tocopherol. Tocofersolan is an oral treatment of vitamin E deficiency due to digestive malabsorption in pediatric patients with congenital chronic cholestasis or hereditary chronic cholestasis. It was approved by the European Medicines Agency (EMA) in June 2009 under the market name Vedrop. Moreover, the agent is capable of demonstrating antioxidant effects that make it a popular component to include in cosmetics and pharmaceuticals as well.

    In addition to the above, tocofersolan has been studied as a promising application as an absorption enhancer in drug delivery

    Structure

     

    Shop D-α-Tocopherol polyethylene glycol 1000 succinate-Detailed Image 1

    Molecular Formula

    C35H58O6

    Molecular Weight

    574.840

    Appearance

    White to yellow wax solid

    Quality Standard

    USP, EP, BP, CP

    Shipping Condition

    Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

    Storage Condition

    Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

    Shelf Life

    >2 years if stored properly

    Sample package

    Aluminium foil bag

    Commercial package

    Aluminium Tin, Fiber drum

    Origin

    China

    Certificates

    Basic Info
    Product Name:

    α-Tocopheryl polyethylene glycol succinate

    Other Name:

    Poly(oxy-1,2-ethanediyl),α-[4-[[(2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl]oxy]-1,4-dioxobutyl]-ω-hydroxy-;Poly(oxy-1,2-ethanediyl),α-[4-[[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl]oxy]-1,4-dioxobutyl]-ω-hydroxy-,[2R-[2R*(4R*,8R*)]]-;Mono[2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanyl] succinate,polyoxyethylene ether;Tocofersolan;D-α-Tocopherol polyethylene glycol 1000 succinate;TPGS;D 1T;α-Tocopherol polyethylene glycol succinate;d-α-Tocopheryl poly(ethylene glycol) 1000 succinate;Tocophersolan;α-Tocopheryl polyethylene glycol succinate;D-α-Tocopheryl polyethylene glycol succinate;d-α-Tocopheryl polyethylene glycol succinate;Vitamin E-TPGS;Eastman Vitamin ETPGS;VE-TPGS 1000;VitE-TPGS;Speziol TPGS Pharma;Kolliphor TPGS;D-α-Tocopherol acid polyethylene glycol 1000 succinate;TPGS 1000;TPGS 400-1000;TPGS 1500;Polyethylene glycol vitamin E succinate;Ethoxylated vitamin E succinate;d-α-Tocopheryl polyethylene glycol succinate;Vedrop;30999-06-5;32408-94-9;58829-13-3;75139-00-3;162849-98-1;249747-47-5;1365321-30-7;2614417-59-1

    CAS No.:

    9002-96-4

    Molecular Formula:

    (C2H4O)nC33H54O5

    InChIKeys:

    InChIKey=AOBORMOPSGHCAX-UHFFFAOYSA-N

    Molecular Weight:

    574.83

    Exact Mass:

    662.475769

    EC Number:

    618-345-6

    Characteristics
    PSA:

    100.52000

    XLogP3:

    8.38890

    Appearance:

    Clear, colorless solid.

    Density:

    1.01g/cm3

    Melting Point:

    34-38ºC

    Boiling Point:

    662.7ºC at 760mmHg

    Flash Point:

    195.4ºC

    Refractive Index:

    1.496

    Storage Conditions:

    Vitamin E polyethylene glycol succinate is stable at ambient room temperature for up to 4 years. It reacts with alkalis and acids. Aqueous solutions of vitamin E polyethylene glycol succinate are stable over a pH range of 4.5–7.5 and can be further stabilized with propylene glycol.

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

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