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3,5-diiodo-L-thyronine 99%

Name: 3,5-diiodo-L-thyronine 99%
Brand: HyperChem
SKU: pr2410021011
Price: 4.85 USD
Availability: InStock

2 Inquiries

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CAS No.:

1041-01-6

Grade:

Pharmaceutical Grade

Content:

99.5%

Port:

any port in china

Brand:

HyperChem

Packaging:

1g/bottle, 10g/bottle, 1kg/Tin

Price valid (until):

2024-11-02

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	3,5-Diiodo-L-thyronine
CAS number	1041-01-6
Synonym	3,5-Diiodo-L-thyronine 1041-01-6 Diiodothyronine 3,5-Diiodothyronine, L- O-(4-Hydroxyphenyl)-3,5-diiodo-L-tyrosine
Related CAS	NA
Description	(2S)-2-amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid ,3,5-Diiodo-L-thyronine (3,5-T2) is an endogenous metabolite of thyroid hormones that has emerged as a biologically active iodothyronine.
Structure
Molecular Formula	C15H13I2NO4
Molecular Weight	525.08 g/mol
Appearance	White to off-white crystalline powder
Quality Standard	USP,Pharmaceutical grade, with a minimum purity of 98% or higher depending on the supplier
Shipping Condition	Shipped under controlled conditions, usually at ambient or cold temperatures based on the customer's request
Storage Condition	Dry, dark and at 2~8 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag, Bottle
Commercial package	Aluminium Tin
Origin	China

More Info 3,5-Diiodo-L-thyronine

3,5-Diiodo-L-thyronine (T2) is a biologically active thyroid hormone derivative known for its potential role in regulating metabolism and energy expenditure. It is an iodinated thyronine that plays a role in mitochondrial function and fat oxidation.

Mechanism of Action

3,5-Diiodo-L-thyronine stimulates metabolic rate by influencing the activity of mitochondria, leading to increased energy expenditure.
It is a product of peripheral metabolism of thyroid hormones (T4 and T3) and is known to regulate lipid metabolism, potentially aiding in fat loss.
Unlike T3, T2 has a more targeted action on lipid metabolism without significantly affecting overall heart rate and protein catabolism.

Pharmacokinetics

Bioavailability: The bioavailability of 3,5-Diiodo-L-thyronine is not well-studied in humans, but it is known to be metabolized in the liver after ingestion.
Half-life: It is metabolized quickly compared to other thyroid hormones, with a shorter half-life, though specific pharmacokinetic data remain limited.
Elimination: 3,5-Diiodo-L-thyronine is eliminated through metabolic pathways in the liver and kidneys, ultimately being excreted in urine.

Clinical Uses

Experimental use: 3,5-Diiodo-L-thyronine is currently under research for its potential to treat metabolic disorders, such as obesity and hyperlipidemia, due to its ability to enhance fat metabolism.
Therapeutic potential: While not yet approved for clinical use in humans, it shows promise as a therapeutic agent for weight management and metabolic health in various experimental studies.

Side Effects

The side effects associated with 3,5-Diiodo-L-thyronine are not fully understood, as it is still being studied. However, based on its similarity to other thyroid hormones, potential side effects may include:

Mild gastrointestinal symptoms: Nausea or upset stomach.
Thyroid-related effects: Changes in thyroid function, though these are likely less significant compared to T3 and T4.
Metabolic effects: Increased energy expenditure and potential for mild hypermetabolism.

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Basic Info

Product Name:

Diiodothyronine

Other Name:

L-Tyrosine,O-(4-hydroxyphenyl)-3,5-diiodo-;Alanine,3-[4-(p-hydroxyphenoxy)-3,5-diiodophenyl]-,L-;O-(4-Hydroxyphenyl)-3,5-diiodo-L-tyrosine;3,5-Diiodo-L-thyronine;Diiodothyronine;Diiodo-L-thyronine;3,5-Diiodothyronine;L-3,5-Diiodothyronine;L-T2;L-Diiodothyronine;NSC 90469;(2S)-2-Amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid;(2S)-2-Amino-3-[4-(4-hydroxyphenoxy)-3,5-diiodophenyl]propanoic acid;30804-67-2;243965-18-6

CAS No.:

1041-01-6

Molecular Formula:

C15H13I2NO4

InChIKeys:

InChIKey=ZHSOTLOTTDYIIK-ZDUSSCGKSA-N

Molecular Weight:

525.08

Exact Mass:

525.08

EC Number:

213-867-7

UNII:

CAL3MRM51F

HScode:

29225090

Categories:

Drug Metabolism

Characteristics

PSA:

92.8

XLogP3:

1.1

Appearance:

Off-white solid

Density:

2.095±0.06 g/cm3(Predicted)

Melting Point:

255 °C

Boiling Point:

559.4±50.0 °C(Predicted)

Flash Point:

292.1±30.1 °C

Refractive Index:

1.726

Storage Conditions:

2-8ºC

Vapor Pressure:

2.39E-13mmHg at 25°C

Collision Cross Section:

198.5 Å² [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|189.4 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|188.2 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]

See More Diiodothyronine Properties 

Hazard Identification

Classification of the substance or mixture

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	H412 Harmful to aquatic life with long lasting effects
Prevention	P273 Avoid release to the environment.
Response	none
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Diiodothyronine Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
Russia	3,5-Diiodo-L-thyronxine	25 KG	Oct 1, 2024
India	3,5-Diiodo-L-thyronine	25 KG	May 8, 2026

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