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Factory Supply High Purity 99% Food Grade Nicotinamide Riboside Chloride/ Nr Powder CAS 23111-00-4

Name: Factory Supply High Purity 99% Food Grade Nicotinamide Riboside Chloride/ Nr Powder CAS 23111-00-4
Brand: Source Herb
SKU: pr2410111249
Price: 100 USD
Availability: InStock

5 Inquiries

Unit Price: Get Latest Price 

CAS No.:

23111-00-4

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

Source Herb

Packaging:

25kg/Carboard Drum

Price valid (until):

2024-11-11

Contact Supplier

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Hangzhou Source Herb Bio-Tech Co., Ltd

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average Lead Time:

7 days

Qualification:

Main Products:

Red Yeast Rice,Saw Palmetto Extract,Berberine HCL

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Product Description
Seller Information
Inquiry History

Description

Nicotinamide Riboside Chloride

Product Description:
Product Name: Nicotinamide Riboside Chloride
Appearance: White Powder
CAS No: 23111-00-4
Purity: 99%
MF: C11h15cln2o5

Nicotinamide riboside chloride is a crystal form of Nicotinamide riboside (NR) chloride which is a nicotinamide adenine
dinucleotide (NAD[+]) precursor vitamin. Nicotinamide riboside chloride increases NAD[+] levels and activates SIRT1 and SIRT3,culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside chloride is used in dietary supplements

Product Functions:

1. The proper digestion and absorption of protein and fat;

2. To help in the essential amion acid tryptophan is converted to nicotinic acid;

3. To prevent all kinds of nerves, skin diseases;

4. Alleviate vomiting;

5. Promote the nucleic acid Synthesis, to prevent the aging of tissues and organs;

6. Lower the result of taking antidepressants caused by dry mouth and dysuria

7. Slow night muscle spasms, cramps paralysis and other symptoms of hand,foot and neuritis;

8. Is the natural the diuretic.

9. Treatment of congenital hypofunction of metabolism;

10. Prevent and treat vitamin B6 deficiency;

11. Supplement to patients who need to consume more vitamin B6;

12. Treatment of carpal tunnel syndrome.

FAQ:

What's the MOQ?

Generally the MOQ is 1kg, Best 25KG/DRUM

Is there any discount?

Yes, we will give you the best discount according to the size of your order!

How can I confirm the product quality before placing orders?

We will send you the existing sample or prepare the sample according to your request and send it to you for your confirmation！

How do you treat quality complaint?

If the quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately！

How to contact with us ?

Through SKYPE, WHATSAPP, WeChat, and E-mail.

How to place an order & payment ?

(1). Conduct product consultation,

(2). Determine the sample,

(3).After the sample quality meets the requirements, send us the PO,

(4). We reply to PI

(5). The customer completes the payment,

(6). Receive payment for goods, export products,

(7). The customer receives the goods and completes the order.

Cooperative customers:

Our products are exported to European and American countries.

It also has a large customer base in Southeast Asia and other regions.

After-sale service:

If the quality problem is confirmed to be caused by us, we will replace the goods or refund your payment immediately！

100% responsible person, safe and reliable, integrity first.

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ECHEMI Editorial Reference

Nicotinamide Riboside Chloride is the chloride salt form of nicotinamide riboside(NR).NR is a new form pyridine-nucleoside of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide(NAD) or NAD+ . Nicotinamide riboside chloride is a crystal form of Nicotinamide riboside (NR) chloride. Nicotinamide riboside chloride increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities. Nicotinamide riboside chloride is used in dietary supplements.
Nicotinamide riboside chloride (NR-CL) is structurally a quaternary ammonium salt containing a sensitive N-glycosidic bond that spontaneously cleaves in aqueous solution, yielding nicotinamide and d-ribose degradation products (Figure 1). NR-CL exhibits three crystalline forms: Type A, Type B, and Type C. Forms A and B represent true polymorphs of the anhydrous form, whereas form C constitutes a pseudo-polymorphic form as a methanesulfonate solvate. The B form exhibits a higher crystal density (1.591 Mg/m³) and a higher melting/decomposition temperature (123°C) compared to the A form (1.512 Mg/m³, 119°C), making it the most stable crystalline form. The crystal structure of Form B(Figure 2) is orthorhombic P212121 space group, with a = 7.0008(11) Å, b = 9.6465(15) Å, c = 17.971(3) Å, V = 1213.7(3) Å³, and Z = 4.
Nicotinamide riboside (NR) was first described in 1944 as a growth factor, termed Factor V, for Haemophilus influenza, a bacterium that lives in and depends on blood. Factor V, purified from blood, was shown to exist in three forms: NAD+, NMN and NR. NR was the compound that led to the most rapid growth of this bacterium.Notably, H. influenza cannot grow on nicotinic acid, nicotinamide, tryptophan or aspartic acid, which were the previously known precursors of NAD+.In 2000, yeast Sir2 was shown to be an NAD+-dependent protein lysine deacetylase, which led several research groups to probe yeast NAD+ metabolism for genes and enzymes that might regulate lifespan. Biosynthesis of NAD+ in yeast was thought to flow exclusively through NAMN (nicotinic acid mononucleotide).When NAD+ synthase (glutamine-hydrolysing) was deleted from yeast cells, NR permitted yeast cells to grow. Thus, these Dartmouth College investigators proceeded to clone yeast and human nicotinamide riboside kinases and demonstrate the conversion of NR to NMN by nicotinamide riboside kinases in vitro and in vivo. They also demonstrated that NR is a natural product found in cow’s milk.

Basic Info

Product Name:

Nicotinamide riboside chloride

Other Name:

Nicotinamide riboside chloride;Nicotinamide Riboside.Cl;Nicotimide riboside chloride;Pyridinium, 3-(aminocarbonyl)-1-β-D-ribofuranosyl-, chloride (1:1);3-carbamoyl-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium chloride;3-Carbamoyl-1-(β-D-ribofuranosyl)pyridinium chloride;3-Carbamoyl-1-beta-D-ribofuranosylpyridinium chloride;Nicotinamide Riboside Chloride（NRC）

CAS No.:

23111-00-4

Molecular Formula:

C11H15ClN2O5

InChIKeys:

YABIFCKURFRPPO-TUHHAUDNNA-N

Molecular Weight:

290.7

EC Number:

200-184-4

Color/Form:

White

HScode:

2938909090

Categories:

Cardiovascular Agents

Characteristics

Water Solubility:

10mg/mL, clear, colorless

Critical Temperature & Pressure:

under inert gas (nitrogen or Argon) at 2-8°C

See More Nicotinamide riboside chloride Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Nicotinamide riboside chloride Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Red Yeast Rice,Saw Palmetto Extract,Berberine HCL

Location:
Room 207-3, 2nd Floor, Building C, 16 Longtan Road, Cangqian Street, Yuhang District, Hangzhou City, Zhejiang Province

Payment Terms:
TT against copy of documents,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2016

Inquiry History

5 Inquiries

Country	Product	Purchase Quantity	Date Posted
United States	Nicotinamide riboside chloride 98% NR 23111-00-4	5 MT	Jun 22, 2024
United States	nicotinamide riboside chloride	1 KG	Feb 27, 2024
Germany	Nicotinamide Riboside Chloride	500	Jun 22, 2026
Philippines	NRcl	1 KG	Mar 1, 2026
United States	β-Nicotinamide Riboside Chloride	1 KG	Nov 22, 2024

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Factory Supply High Purity 99% Food Grade Nicotinamide Riboside Chloride/ Nr Powder CAS 23111-00-4

Product Description

Seller Information