Supply High Quality CP Standard Citicoline Sodium/Citicoline/CDP-choline CAS 33818-15-4

Citicoline Sodium More Info

Citicoline sodium, also known as cytidine-5'-diphosphocholine (CDP-choline), is a compound that serves as a precursor for the synthesis of phosphatidylcholine, a vital component of cell membranes. It has garnered attention for its potential neuroprotective effects and therapeutic applications in various neurological conditions.

Mechanism of Action

Citicoline is believed to exert its effects through several mechanisms:
1. Choline Donor: It acts as a donor of choline, which is essential for the synthesis of phospholipids, particularly phosphatidylcholine, crucial for maintaining cell membrane integrity and function.
2. Neuroprotective Properties: Citicoline may enhance neuronal survival and function by modulating phospholipid metabolism and neurotransmitter levels, thereby improving cognitive function in conditions such as stroke and bipolar disorder.
3. Angiogenesis: Recent studies suggest that citicoline induces angiogenesis, enhancing blood flow to the brain, which may further support neuronal health

Applications

Citicoline sodium has been investigated for several clinical applications:
Neurological Disorders: It is used in the treatment of stroke, bipolar disorder, hypomania, and cocaine dependence24.
Cognitive Enhancement: Some studies indicate potential benefits in improving cognition in patients with central nervous system disorders3.
Supportive Care: Citicoline is also considered for supportive care in various psychiatric conditions

Routes of Administration

Citicoline can be administered through various routes:
Oral Administration: Commonly available in tablet form.
Parenteral Administration: Can be given intravenously or intramuscularly, which allows for faster absorption and action.

Safety and Side Effects

Citicoline is generally well-tolerated, with few reported side effects. Commonly noted side effects include:
Gastrointestinal disturbances (e.g., nausea)
Headaches
Insomnia
Serious adverse effects are rare, making it a relatively safe option for many patients

Pharmacokinetics

The pharmacokinetics of citicoline sodium reveal important characteristics:
Absorption: After administration, citicoline is quickly metabolized into choline and cytidine. Studies show that plasma concentrations peak at approximately 15 minutes post-intravenous administration, with a second peak around 5 hours later.
Distribution: It has a moderate ability to cross the blood-brain barrier, which is crucial for its neuroprotective effects.
Metabolism: Citicoline undergoes rapid hydrolysis to yield its active metabolites, including cytidine monophosphate (CMP) and phosphocholine (PCho).

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

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Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
FedEx  UPS  DHL  EMS                               
Fast: 3-7 days around, high cost, door to door service

By Air                                        
Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

By Sea
Suitable for more than 500kg      
Fast: 7-45 days, low cost, port to port, professional broker needed 

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

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HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.