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High Quality 99% Dabigatran Etexilate CAS 211915-06-9 Powder Fast Shipping Good Price

Name: High Quality 99% Dabigatran Etexilate CAS 211915-06-9 Powder Fast Shipping Good Price
Brand: HyperChem
SKU: pr2412111223
Price: 140 USD
Availability: InStock

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CAS No.:

211915-06-9

Grade:

Pharmaceutical Grade

Content:

99.5%

Port:

Hangzhou

Brand:

HyperChem

Packaging:

1kg/Bag

Price valid (until):

2025-01-11

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information

Description

Name	Dabigatran Etexilate
CAS number	211915-06-9
Synonym	BIBR 953; BIBR-953; BIBR953; Dabigatran Etexilate; Pradaxa and Prazaxa
Description	Dabigatran, also known as BIBR 953, is an oral anticoagulant from the class of the direct thrombin inhibitors. It is being studied for various clinical indications and in some cases it offers an alternative to warfarin as the preferred orally administered anticoagulant ("blood thinner") since it does not require blood tests for international normalized ratio (INR) monitoring while offering similar results in terms of efficacy. There is no specific way to reverse the anticoagulant effect of dabigatran in the event of a major bleeding event, unlike warfarin, although a potential dabigatran antidote (pINN: idarucizumab) is undergoing clinical studies. It was developed by the pharmaceutical company Boehringer Ingelheim.
Structure
Molecular Formula	C34H41N7O5
Molecular Weight	627.73 g/mol
Appearance	White powder
Quality Standard	99%
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 2~8 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag, Bottle
Commercial package	Aluminium Tin
Origin	China

Dabigatran Etexilate More Info

Dabigatran Etexilate is an oral anticoagulant medication classified as a direct thrombin inhibitor. It functions by preventing blood clot formation in various clinical settings. Below is a detailed overview of this product:

Mechanism of Action

Dabigatran Etexilate is a prodrug that is converted into its active form, dabigatran, in the body. It directly inhibits thrombin (factor IIa), an essential enzyme in the coagulation cascade, thereby preventing the conversion of fibrinogen to fibrin. This action reduces the ability of blood to form clots.

Indications

Dabigatran Etexilate is used for several clinical indications, including:

Non-valvular atrial fibrillation: It is indicated for the prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation.

Venous thromboembolism (VTE): It is used for the treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), and for the prevention of recurrent VTE.

Postoperative prophylaxis: It may be utilized in patients who have undergone certain types of surgeries, such as knee or hip replacement, to prevent thromboembolic events.

Dosing and Administration

Dabigatran Etexilate is typically administered in capsule form. Dosing varies based on indications, kidney function, and other patient-specific factors. Common dosing regimens include:

For non-valvular atrial fibrillation: The typical dosage is 150 mg taken orally twice daily, although a lower dose may be considered for some patients.

For VTE treatment: A standard usage is 150 mg taken orally twice daily after an initial treatment period with a parenteral anticoagulant.

Side Effects

Potential side effects associated with Dabigatran Etexilate include:

Bleeding: The most significant risk is bleeding, which can occur in various forms such as gastrointestinal bleeding, intracranial hemorrhage, and other serious bleeding events.

Gastrointestinal issues: Some patients may experience dyspepsia, nausea, vomiting, or diarrhea.

Others: Additional reported effects may include headache and skin rash.

Contraindications and Precautions

Contraindications: Dabigatran Etexilate should not be used in patients with active bleeding, severe renal impairment, or hypersensitivity to the drug or its components.

Precautions: Monitoring renal function is essential during treatment, as dose adjustment may be necessary for patients with impaired renal function. It is also important to assess for potential drug interactions with other medications.

Conclusion

Dabigatran Etexilate is a commonly used oral anticoagulant with proven efficacy in preventing and treating thromboembolic disorders. While it offers certain advantages over traditional anticoagulants, such as not requiring routine monitoring, careful patient selection, and consideration of dosing adjustments are critical to managing the associated risks effectively. Always consult healthcare professionals for appropriate guidance and management.

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

Bank transfer

PayPal

Bitcoin...

Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express
FedEx UPS DHL EMS
Fast: 3-7 days around, high cost, door to door service

By Air
Suitable for more than 50kg
Fast: 3-7 days, hight cost, port to port, professional broker needed

By Sea
Suitable for more than 500kg
Fast: 7-45 days, low cost, port to port, professional broker needed

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders:
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders:
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Certificates

Basic Info

Product Name:

Dabigatran etexilate

Other Name:

β-Alanine,N-[[2-[[[4-[[[(hexyloxy)carbonyl]amino]iminomethyl]phenyl]amino]methyl]-1-methyl-1H-benzimidazol-5-yl]carbonyl]-N-2-pyridinyl-,ethyl ester;Dabigatran etexilate;BIBR 1048;Prazaxa;1428422-77-8

CAS No.:

211915-06-9

Molecular Formula:

C34H41N7O5

InChIKeys:

InChIKey=KSGXQBZTULBEEQ-UHFFFAOYSA-N

Molecular Weight:

627.74

Exact Mass:

627.73

EC Number:

1592732-453-0

UNII:

2E18WX195X

HScode:

2933990090

Categories:

Other Chemical Drugs

Characteristics

PSA:

152

XLogP3:

3.8

Appearance:

Solid

Density:

1.2±0.1 g/cm3

Melting Point:

128-129 °C

Boiling Point:

827.9°C at 760 mmHg

Flash Point:

454.5±37.1 °C

Refractive Index:

1.615

Water Solubility:

1.8mg/ml, partly soluble

Vapor Pressure:

1.49E-27mmHg at 25°C

See More Dabigatran etexilate Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Dabigatran etexilate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.
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