Supply Animal Antibiotics CAS 1264-72-8 Polymyxin E/Colistin Sulfate/Colistin Sulphate HuaMan

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Product Description 

What is Polymyxin E/Colistin Sulfate/Colistin Sulphate ?

Colistin sulfate, white or near-white powder, odorless, bitter and hygroscopic, soluble in water, slightly soluble in ethanol, etc., free base slightly soluble in water. Stable in the range of PH3-7.5. Colistin sulfate is produced by polymyxa, and has strong antibacterial activity against Gram-negative bacteria, and is used for intestinal diseases caused by Gram-negative bacteria. It is better combined with the sulfadiazine effect.

What is Colistin sulphate？

Colistin sulfate, also known as colistin sulfate, Colistin, polymyxin E (PolymyxinE), antienemy, etc., is a white or near white powder, odorless, bitter and hygroscopic, easy to Soluble in water, slightly soluble in methanol and ethanol, almost insoluble in acetone, ether, etc., free base is slightly soluble in water. Stable within the range of PH3-7.5..

Basic Information 

Colistin sulfate is an antibiotic polypeptide which possesses activity mainly against Gram negative bacteria, and in veterinary medicine is used orally for the treatment or prevention of enteritis in production animals. 

Colistin sulfate is highly effective against strains of Escherichia coli, Pseudomonas aeruginosa, Salmonella spp., Haemophilus spp., Shigella spp., Pasteurella spp., Brucella spp., Aerobacter aerogenes and Bordetella bronchiseptica. Gram positive bacteria are generally less sensitive, but there are some sensitive strains such as Staphylococcus spp., Bacillus spp., Streptococcus pyogenes and Corynebacterium spp.
 

Items	Specifications
Product name	Polymyxin E/Colistin Sulfate/Colistin Sulphate
CAS No.	1264-72-8
MF	2(C52H98N16O13).5(H2SO4)
MW	2801.27
EINECS.No	215-034-3
Melting Point	200-220°C
Appearance	White powder
Shelf Life	2 Years When Properly Stored
Storage	Keep in a cool, dry, dark location in a tightly sealed container or cylinder.

Usage

1. A growth promoter used in Peru in poultry and pork production is sulfate colistin, an antibiotic belonging to the polymyxin group. 
2. Salmonellosis is an important disease in poultry and pork production, because of the implications that arise in Public Health, the restrictions on the marketing of products from infected farms and the impact on health programs of farms. The most common clinical manifestation of this disease is enteritis, which is often presented as a bloody or profuse watery diarrhea accompanied by fever, but you can see a broad spectrum of clinical symptoms, such as acute septicemia,abortion, arthritis, necrosis on extremities and respiratory disease.

Function 

Colistin sulfate is highly effective against strains of Escherichia coli,Pseudomonas aeruginosa, Salmonella spp., Haemophilus spp.,Shigella spp., Pasteurella spp., Brucella spp., Aerobacter aerogenes and Bordetella bronchiseptica. Gram positive bacteria are generally less sensitive, but there are some sensitive strains such asStaphylococcus spp., Bacillus spp., Streptococcus pyogenes andCorynebacterium spp.

Application of Colistin sulphate

It is an antibiotic drug, used to treat intestinal diseases caused by Gram-negative bacilli, and has a certain growth-promoting effect.

Specification

Test Item	Standard Specification	Test Data
Identification	a)       TLC	Complies
	b)      Color reaction	Complies
	c)      Sulfate reaction	Complies
Infrared absorption	According with IR reference spectrum	Meets the requirement
Loss on drying	≤8.0%	3.20%
PH	5.0-7.5	6.6
Residue on ignition	Not more than 0.05% of weight	0.03%
Substances insoluble in  sodium carbonate	The solution is clear	Clear
Partical size	0.5% max on USP sieve 180(um)	Meets the requirement
Heavy metals	≤10ppm	10ppm
Assay	Not less than 680 ug/mg	692ug/mg
Conclusion	The sample is in compliance with the BP2005

Tirzepatide (LY3298176) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist that is being developed for the treatment of type 2 diabetes. Tirzepatide (LY3298176) shows significantly better efficacy with regard to glucose control and weight loss than do Dulaglutide.

Tirzepatide, also known as LY 3298176, is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist. Tirzepatide has a greater affinity to GIP receptors than to GLP-1 receptors, and this dual agonist behavior has been shown to produce greater reductions of hyperglycemia compared to a selective GLP-1 receptor agonist. Signaling studies reported that tirzepatide mimics the actions of natural GIP at the GIP receptor. Tirzepatide was approved for improving blood sugar control in adults with type 2 diabetes, as an addition to diet and exercise.

Appearance: Powder

Purity: >98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility: To be determined

Shelf Life: >2 years if stored properly

Drug Formulation: To be determined

Stock Solution Storage: 0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code: 2934.99.9001

Quality:   Purity above 99%, directly produced by the manufacturer, can accept quality testing, and can also customize any content of powder, liquid, oil, etc.

Transport:   We can accept sea freight, air freight, and express delivery, with a guarantee time of 1-2 weeks and a customs clearance rate of over 99%. Even if the goods are detained, you can resend the freight and I will resend the goods.

Service:   We can provide sterile water for you to directly mix and inject freeze-dried powder. In addition to powder, we also have liquids, water-based agents, oils, tablets, and professional customized synthesis routes. We provide you with professional guidance on product use, product synthesis, and product customization.

Price:   We do not engage in price wars. Firstly, our quality can be guaranteed; Secondly, our transportation efficiency and customs clearance rate can be guaranteed; Thirdly, we will provide you with the highest quality service, in any aspect. If you have any questions, I will have the answer.

HuaMan Bio acquired early mastery of development and manufacturing of peptides, the short chain amino acids linked by peptide bonds that have enabled new generations of small molecule drugs that closely mimic the body's natural pathways. Now HuaMan Bio possesses first-class capabilities to manufacture peptides at industrial scale and in full compliance with the strictest Good Manufacturing Practice (cGMP) standards.pharmaceutical raw materials, food and feed additives, veterinary drugs and other fields, the enterprise adhering to provide customers with quality service, supply high-quality products, "world peace and health" as its responsibility, the company adhering to the "meet all customer requirements for products" as the service concept, Guarantee "provide qualified products" as the service principle, so that you get "God-like" noble shopping enjoyment. Our company has more than 1000 kinds of polypeptides, raw materials inventory, at any time to meet the various needs of customers for products. Is your best partner.

Q1: What's your MOQ?
A:It depends on different products,we can accept sample order or provide free sample for your test.

Q2:How about delivery leadtime?
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)

Q3: Is there a discount?
A:Different quantity has different discount.

Q4:How to start orders or make payments?
A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T.

Q5: How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.

Q6. We don't know you at all, how can we trust you?
A: You are always warm welcomed to visit us at any time. Commitment is the No.1 Point of our Enterprise's Value.

Q7.Do you test all your goods before delivery?
A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.