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5-Hydroxytryptophan /5-HTP

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CAS No.:

4350-09-8

Port:

Shanghai

Packaging:

1kg/drum

Price valid (until):

2025-03-31

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BrightGene Health Technology Co., Ltd

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

APIs,Veterinary,Cosmetic Ingredients,Peptides,intermediates,food ingredients

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Product Description
Seller Information
Inquiry History

Description

Product Detail

5-Hydroxytryptophan (5-HTP) is a kind of amino acids. It acts as a precursor to serotonin (serotonin,5-HT) in the human body (and in turn as a precursor to melatonin). Several double-blind studies have shown that 5-HTP can increase brain serotonin levels, improve depression and promote melatonin production, improve sleep quality, and suppress appetite.

5-HTP is classified as a pharmaceutical ingredient in some countries. In the United States, United Kingdom and Canada, 5-HTP is marketed as a dietary supplement.

Taking 5-HTP converts it into serotonin in the body, but serotonin can't cross the blood-brain barrier into the brain. Therefore, 5-HTP must first pass through the blood-brain barrier and then be converted into serotonin in the brain in order to truly play the role of stabilizing mood and promoting sleep quality. After taking 5-HTP orally, about one-third to one-half can actually be converted to serotonin in the brain, and a large portion will be converted to serotonin before entering the brain's blood circulation.

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Items	Specifications

Basic Info

Product Name:

L-5-Hydroxytryptophan

Other Name:

5-hydroxy-l-tryptopha;pretonine;L-2-AMINO-3-(5-HYDROXYINDOLYL)PROPIONIC ACID;L-5-HYDROXYTRYPTOPHAN HYDRATE;L-5-HYDROXYTRYPTOPHAN;2-AMINO-3-(5-HYDROXY-1H-INDOL-3-YL)PROPIONIC ACID;(-)-5-HYDROXY-L-TRYPTOPHAN;5-HYDROXY-L-TRP-OH

CAS No.:

4350-09-8

Molecular Formula:

C11H12N2O3

InChIKeys:

LDCYZAJDBXYCGN-VIFPVBQESA-N

Molecular Weight:

220.22

Exact Mass:

220.22

BRN:

88200

EC Number:

224-411-1

UNII:

C1LJO185Q9

UN Number:

2811

TSCA:

TSCA listed

DSSTox ID:

DTXSID1025437

NCI Thesaurus Code:

C52181

Color/Form:

white

ATC Code:

N - Nervous system

HScode:

29339990

Categories:

Nutrition Supplements

Characteristics

PSA:

99.3

XLogP3:

-2.051

Appearance:

white solid

Density:

0.902 g/mL at 25 °C (lit.)

Melting Point:

270 °C (dec.) (lit.)

Boiling Point:

361.16°C (rough estimate)

Flash Point:

175 °F

Refractive Index:

n20/D1.4850(lit.)

Water Solubility:

Slightly soluble

Storage Conditions:

2-8°C

Vapor Pressure:

2.55X10-11 mm Hg at 25 deg C (est)

Specific rotation:

-32.5 º (c=1,H2O on dry basis)

PKA:

2.22±0.10(Predicted)

Henrys Law Constant:

Henry's Law constant = 2.1X10-18 atm-cu m/mol at 25 °C (est)

Collision Cross Section:

152.2 Å² [M+Na]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|148.86 Å² [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|157.88 Å² [M+H]+ [CCS Type: DT, Method: stepped-field]|156.47 Å² [M+Na]+ [CCS Type: DT, Method: stepped-field]|153.72 Å² [M-H]- [CCS Type: DT, Method: stepped-field]|149.8 Å² [M-2H+Na]-

Experimental Properties:

Hydroxyl radical reaction rate constant = 2.39X10-10 cu cm/molec-sec at 25 °C (est)|Crystals; specific optical rotation: -32.5 deg at 20 °C/D (water); +16.0 deg at 20 °C/D (4 N HCl) /l-form/|Crystals; specific optical rotation: +32.2 deg at 20 °C/D (water) /d-form/

Air and Water Reactions:

L-5-Hydroxytryptophan is sensitive to air. Slightly water soluble .

Reactive Group:

Phenols and Cresols

Reactivity Profile:

L-5-Hydroxytryptophan reacts with bases. .

Critical Temperature & Pressure:

2-8°C

See More L-5-Hydroxytryptophan Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 3, Oral

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H301 Toxic if swallowed
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P301+P316 IF SWALLOWED: Get emergency medical help immediately. P321 Specific treatment (see ... on this label). P330 Rinse mouth.
Storage	P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More L-5-Hydroxytryptophan Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
APIs,Veterinary,Cosmetic Ingredients,Peptides,intermediates,food ingredients

Location:
T2-805,European and American Financial City,Cangqian Street,Yuhang District,Hangzhou,China.(zip code:311121)

Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
20

Total Annual Revenue:
$10 million-$25 million

Total Employees:
11-50

Year of Establishment:
2009

Hangzhou Holypharm Biotech Co., Ltd was founded in Hangzhou in 2006. Over the decades, Holypharm has maintained sound development and rapid global expansion. Based on China and looking at the world, the Holypharm has become a leading professional health industry chain service group in China.

Holypharm supplies different kinds of products, covering the whole field of health industry, including human APIs, veterinary APIs, intermediates, food additives, natural nutrition ingredients, feed additives, cosmetic additives, , medical devices, etc. Based on the deep strategic cooperation with Brightgene Pharmaceutical Company, and integrated production advantages, Holypharm's marketing network has spread over more than 40 countries and regions on five continents, providing professional service for global customers.

With a commitment to quality and customer satisfaction, Holypharm has become a trusted name in the industry. Our strong product line includes like a range of high-quality tripeptide copper, (±)-Lipoic acid in cosmetics, Sameglutide Tirzepatide in the field of metabolism which are available at competitive prices. Holypharm has established itself as a reliable supplier of chemical products on the echemi.com.

In the future, Holypharm will expand its business in the CDMO and OEM industry, connect the investment, R&D and production, and gradually become a integrated enterprise. Holypharm will stay true to the mission of serving the global health industry and helping create a win-win situation.

Inquiry History

1 Inquiries

Country	Product	Purchase Quantity	Date Posted
South Korea	5-HTP/5-hydroxytryptophan 30% White powder S15 BLRH/VDK	5 KG	Dec 1, 2025

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