 Home > Biochemical Engineering > Plant Extracts > Phloretin for Sale > Phloretin | Apple Peel Extract | CAS 60-82-2, dihydrochalcone flavonoid for antioxidant & skin brightening, used in nutraceutical & cosmetic raw mater

Phloretin | Apple Peel Extract | CAS 60-82-2, dihydrochalcone flavonoid for antioxidant & skin brightening, used in nutraceutical & cosmetic raw mater buy - large image1

Phloretin | Apple Peel Extract | CAS 60-82-2, dihydrochalcone flavonoid for antioxidant & skin brightening, used in nutraceutical & cosmetic raw mater

Name: Phloretin | Apple Peel Extract | CAS 60-82-2, dihydrochalcone flavonoid for antioxidant & skin brightening, used in nutraceutical & cosmetic raw mater
Brand: PREMIUM INGREDIENT
SKU: pr2501021065
Price: 10 USD
Availability: InStock

TDS 3 Inquiries

Unit Price: Get Latest Price 

CAS No.:

60-82-2

Grade:

Cosmetics Grade

Content:

98%

Port:

shanghai

Brand:

PREMIUM INGREDIENT

Packaging:

25kgs/bag

Price valid (until):

2025-02-02

Contact Supplier

 Chat Now

PREMIUM INGREDIENT CO.,LTD

Company Type:

Manufactory

Location:

United Kingdom

Payment Terms:

TT against copy of documents,L/C

Average Lead Time:

80 days

Qualification:

Main Products:

l-lysine monohydrochloride,dl-methionine,n-acetyl-l-cysteine,l-methionine,glycine,l-cysteine hcl monohydrate

 Visit Store

Product Description
Seller Information
Inquiry History

Description

Product Detail

Basic Information

Phloretin
Synonyms	Apple Peel Extract, Dihydrochalcone polyphenol
CAS No.	60-82-2
Molecular Formula	C₁₅H₁₄O₅
Molecular Weight	274.27 g/mol
Primary Source	Apple Peel (Malus domestica)
Available Form	Fine Powder
Main Active Component	Phloretin ((dihydrochalcone flavonoid)
Specifications	Phloretin 98% (HPLC)
Extraction Method	Solvent extraction, purification and crystallization from apple peel

Product Overview

Phloretin, Cas No.: 60-82-2, is a natural dihydrochalcone flavonoid compound extracted from apple peel. It is widely used as a multi-functional cosmetic active ingredient. It inhibits tyrosinase activity to reduce melanin formation, delivers strong antioxidant effects, and has the unique property of enhancing skin penetration of other active ingredients. The standardized high-purity phloretin powder is mainly applied in skincare formulations, and also studied for nutritional supplement research.

Character

Phloretin appears as white to off-white crystalline powder, soluble in ethanol and other organic solvents, slightly soluble in water. It is a versatile cosmetic active with stable activity, compatible with many cosmetic formulation systems, and can be combined with other skincare actives to boost formula performance.

Main Functions

1.Skin Brightening & Even Tone — Inhibits tyrosinase activity, reduces melanin production, helps fade dark spots and hyperpigmentation, and evens uneven skin tone.

2.Powerful Antioxidant & Anti-Aging — Scavenges free radicals induced by UV and environmental stress, protects skin cells and reduces premature skin aging signs.

3.Natural Transdermal Penetration Enhancer — Improves skin absorption of other cosmetic active ingredients, maximizes the efficacy of compound skincare formulas.

4.Anti-Inflammatory & Soothing Action — Modulates inflammatory response, relieves skin redness and irritation, suitable for sensitive and blemish-prone skin.

5.Glucose Metabolism Support — Supports balanced glucose metabolism, studied for nutritional supplement research.

Applications

1.Cosmetics & personal care: skincare serums, creams and lotions for brightening, anti-photoaging and soothing formulations, used together with other cosmetic active ingredients.

2.Dietary supplements: raw material for research and development of metabolic health formulas.

Packaging & Storage

Packing: 25kg/drum

Storage: Store in cool, dry, dark and ventilated place, avoid high temperature, strong light and moisture

Shelf Life: 24 months under standard sealed storage

ECHEMI Editorial Reference

Phloretin(NSC 407292; RJC 02792) is a dihydrochalcone, a type of natural phenols. Phloretin inhibits the active transport of glucose into cells by SGLT1 and SGLT2.IC50 Value: 49 +/- 12 microM [4]Target: SGLT1/2in vitro: Phlorizin blocks glucose transport across the renal tubule at concentrations in renal blood and tissue in the range of 10-5 to 10-7 M [1]. PT significantly enhanced glycerol release and inhibited the adipogenesis-related transcription factors. PT also promoted phosphoryla
Solid|Pearl white powder; Sweet aroma
Phloretin is a member of the class of dihydrochalcones that is dihydrochalcone substituted by hydroxy groups at positions 4, 2', 4' and 6'. It has a role as a plant metabolite and an antineoplastic agent. It derives from a dihydrochalcone.|Phloretin is a natural dihydrochalcone found in apples and many other fruits.|A natural dihydrochalcone found in apples and many other fruits.

Certificates

Basic Info

Product Name:

Phloretin

Other Name:

1-Propanone,3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-;Phloretin;Propiophenone,2′,4′,6′-trihydroxy-3-(p-hydroxyphenyl)-;3-(4-Hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)-1-propanone;Dihydronaringenin;β-(p-Hydroxyphenyl)phloropropiophenone;β-(p-Hydroxyphenyl)-2,4,6-trihydroxypropiophenone;Phloretol;2′,4′,6′-Trihydroxy-3-(p-hydroxyphenyl)propiophenone;NSC 407292;Naringenin dihydrochalcone;2′,4′,6′-Trihydroxy-3-(4-Hydroxyphenyl)propiophenone;RJC 02792;α,β-Dihydrochalconaringenin;1623753-77-4

CAS No.:

60-82-2

Molecular Formula:

C15H14O5

InChIKeys:

InChIKey=VGEREEWJJVICBM-UHFFFAOYSA-N

Molecular Weight:

274.272

Exact Mass:

274.27

EC Number:

200-488-7

UNII:

S5J5OE47MK

NSC Number:

407292

DSSTox ID:

DTXSID6022393

HScode:

2914501900

Categories:

Plant Extracts

Characteristics

PSA:

XLogP3:

2.6

Appearance:

Crystalline Solid

Density:

1.4±0.1 g/cm3

Melting Point:

263.5 °C (decomp)

Boiling Point:

534.4°C at 760 mmHg

Flash Point:

291.1±20.8 °C

Refractive Index:

1.685

Water Solubility:

H2O: soluble

Storage Conditions:

2-8ºC

Collision Cross Section:

160.7 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

See More Phloretin Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Phloretin Safety Data Sheet 

Seller Information

Business Type: Manufactory
Main Products: l-lysine monohydrochloride,dl-methionine,n-acetyl-l-cysteine,l-methionine,glycine,l-cysteine hcl monohydrate
Location: dongsheng road
Payment Terms: TT against copy of documents,L/C
Average lead Time: 80 days
Total Annual Revenue: $5 million-$10 million
Total Employees: 5-10
Year of Establishment: 2015

Premium Ingredient specializes in supplying and distributing food & feed amino acids, food additives and functional ingredients for more than a decade.

Our food additives portfolio covers phosphates, acidulants, preservatives, sweeteners, thickeners and leavening agents.

Our functional ingredients include vitamins, mineral products, botanical extracts, nutraceutical ingredients, functional fibers & bulking agents.

We serve over 100 clients across food & beverage, dietary supplement, sports nutrition, personal care, pharmaceutical and animal feed sectors, with products exported to dozens of countries worldwide. All our goods are sourced from top-tier Chinese manufacturers with proven expertise and complete management systems.

◆Amino Acids	◆ phosphates	◆ acidulants
◆ preservatives	◆ sweeteners	◆ functional fiber&bulking agent
◆ thickeners	◆ Leavening agents	◆ mineral products
◆ Botanical extracts	◆ vitamins	◆ nutritional products

Backed by over 10 years of industry experience, we provide one-stop-shop solutions combining high-grade products, prompt communication, on-time delivery and real-time market intelligence. Thanks to our long-term deep-rooted partnerships with source manufacturers, we can guarantee sufficient inventory, stable pricing and fast shipment.

Our third-party certifications include ISO9001, ISO14001, HACCP, HALAL, KOSHER, GMP, FAMI-QS and more. You can count on Premium Ingredient as your trusted global raw material supplier.

------------------------------------- Mission------------------------------------

Acting as a bridge between reliable Chinese manufacturers and global buyers, we carefully select partner factories with mature production capabilities and sound management systems. We deliver not only premium-quality raw materials, but also value-added services including market trend updates, supply chain risk alerts, product formulation consultation, consolidated sample shipment and full document support for import compliance. We timely forward overseas customers’ requirements to our partner factories to support product upgrading and achieve mutual growth.

-------------------------------------Our Quality------------------------------------

Our Quality

As a professional ingredient supplier, we do not operate manufacturing facilities. Instead, we build robust quality‑assurance workflows across our whole supply chain to safeguard consistent product performance for every shipment

Strict Supplier Due‑Diligence

Before entering any partnership, we carry out on-site factory visits and assess industry reputation, followed by multi-stage qualification reviews. We validate production qualifications, export track records, quality management systems and complete certification packages. New suppliers must pass sample evaluation, and only fully vetted top-tier factories are admitted to our approved supplier pool

Batch‑by‑batch Document Verification

For every order, we cross‑check factory‑issued test documents against agreed specifications including FCC, USP, EP, AJI, CP or your customized requirements. We will not forward documents to customers until key indicators are fully aligned with specifications. This step avoids inconsistent or mismatched documentation common in raw‑material trade.

Independent Third‑party Testing Coordination

Upon client request, we can arrange independent laboratory inspections from recognized third‑party institutions. We manage sample delivery, test protocol communication and report follow‑up to support your market compliance needs.

Quality Closure & Continuous Improvement

We keep traceable records for all delivered batches. If any quality concern arises, we act as your single point‑of‑contact to trace root causes with source factories, drive corrective actions and deliver practical resolution plans. Client feedback is systematically collected to optimize our supplier management and document‑review procedures.

We provide a comprehensive set of compliance documents to support your import and registration work. Our available documentation includes but is not limited to:

★ ISO Certification ★ Halal Certificate

★ Kosher Certificate ★ IP certificate

★ Haccp certificate ★ Allergens with Glutens

★ GRAS Statement ★ HACCP Program

★ BSE/TSE Statement ★ Certificate of Analysis

★ Country of Origin Certificate ★ Material Safety Data Sheet

★ Flow Chart (product processing) ★ Food Grade Certificate

★ Nutritional Information ★ GMO Statement

★ Specification Sheet

Inquiry History

3 Inquiries

Country	Product	Purchase Quantity	Date Posted
Philippines	China Most Professional Manufacturer Supply High Qulity Phloretin CAS 60-82-2	200 G	May 27, 2026
Philippines	Phloretin	50 MG	May 27, 2026
India	Phloretin	25 G	Dec 12, 2023

Post an enquiry for this product

More Choices Find All Products for Sale 

Product Name	Grade / Content	Price	Supplier Name	Details
China New Type Natural Skin Whitening Raw Material Phloretin CAS 60-82-2	Cosmetics Grade/98	$215-279/KG EXW	Tianjin YR ChemSpec Technology Co.,Ltd.	Inquiry
High Quality Phloretin Powder CAS 60-82-2 Green Apple Extract Skin Whitening Raw Material	Pharmaceutical Grade/99	$150-180/KG FOB	Fulecare	Inquiry
China Most Professional Manufacturer Supply High Qulity Phloretin CAS 60-82-2	Pharmaceutical Grade/99		LEADER BIOCHEMICAL GROUP	Inquiry
Phloretin 99% high purity certified Professional producer Greenbo	Industrial Grade/99		Greenbo Biochem	Inquiry
Factory price high quality Apple Peel Extract phloretin 98%	Cosmetics Grade/98		SHAANXI CREATIVE HERB BIOTECHNOLOGY CO.,LTD	Inquiry