Name | TB500 |
CAS number | 885340-08-9 |
EINECS number | 232-660-2 |
Synonym | TB500; TB 500; TB-500; L-Glutamine, N-acetyl-L-leucyl-L-lysyl-L-lysyl-L-threonyl-L-α-glutamyl-L-threonyl-; |
Description | TB-500 is a synthetic version of an active region. TB 500 promotes endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation. A veterinary preparation known as TB-500 and containing a synthetic version of the naturally occurring peptide LKKTETQ has emerged. The peptide segment (17)LKKTETQ(23) is the active site within the protein thymosin β(4) responsible for actin binding, cell migration and wound healing. The key ingredient of TB-500 is the peptide LKKTETQ with artificial acetylation of the N-terminus. TB-500 is claimed to promote endothelial cell differentiation, angiogenesis in dermal tissues, keratinocyte migration, collagen deposition and decrease inflammation. |
Molecular Formula | C38H68N10O14 |
Molecular Weight | 889.02 g/mol |
Appearance | Solid powder |
Quality Standard | Enterprise Standard |
Assay | ≥98% |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
Storage Condition | Store in cool place. Keep container tightly closed in a dry and well ventilated place. |
Shelf Life | >2 years if stored properly |
Sample package | Aluminium foil bag |
Commercial package | Aluminium Tin, Fiber drum |
Origin | China |
TB-500, is a synthetic peptide that mimics a naturally occurring protein involved in tissue repair and regeneration. It is composed of 43 amino acids and is present in various tissues throughout the body, including blood platelets and wound fluid. TB-500 has gained attention for its potential therapeutic applications in enhancing wound healing, promoting muscle recovery, and improving overall tissue regeneration.
Mechanism of Action
TB-500 exerts its effects through several key mechanisms:
Cell Migration and Angiogenesis: TB-500 promotes the migration of endothelial cells, which are critical for the formation of new blood vessels (angiogenesis). This process is essential for effective tissue repair and regeneration.
Actin Regulation: The peptide binds to actin, a protein that plays a vital role in cell structure and movement. By modulating actin polymerization, TB-500 enhances cell motility and supports the healing process.
Anti-inflammatory Properties: TB-500 has been shown to reduce inflammation in tissues, which can facilitate faster recovery from injuries by minimizing damage and promoting healing.
Applications
TB-500 is primarily investigated for:
Wound Healing: It accelerates the healing process of cuts, abrasions, and more severe injuries by promoting new blood vessel formation and tissue regeneration.
Muscle Recovery: Athletes and individuals recovering from injuries may use TB-500 to enhance muscle repair and reduce recovery time.
Tendon and Ligament Repair: Research suggests that TB-500 may aid in the recovery of tendons and ligaments by promoting cellular migration and collagen deposition.
Neurological Function: Preliminary studies indicate that TB-500 may support neuronal health and promote remodelling in both the central and peripheral nervous systems.
Routes of Administration
TB-500 is typically administered through:
Subcutaneous Injection: The peptide is usually provided as a freeze-dried powder that is reconstituted with bacteriostatic water before injection.
Safety and Side Effects
Common Side Effects
TB-500 is generally considered safe with minimal side effects. However, some users may experience:
Injection site reactions (redness, swelling)
Headaches
Lethargy
Mild gastrointestinal discomfort
Serious Side Effects
Serious adverse effects are rare but can include:
Allergic reactions (e.g., rash or swelling)
Potential immune system modulation leading to increased susceptibility to infections.
Precautions
Due to limited long-term safety data, individuals should consult healthcare professionals before starting TB-500 therapy. It is not approved by regulatory agencies for medical use outside of research settings.
Pharmacokinetics
Absorption and Distribution
TB-500 is rapidly absorbed following subcutaneous administration, allowing for quick action at the site of injury or inflammation.
Metabolism and Excretion
As a peptide, TB-500 is likely metabolized by proteolytic enzymes in the body. Specific details regarding its metabolic pathways are still under investigation.
Q1. Can I get a free sample?
We can send you a samll free sample, and you only need to pay for the shipping cost.
Q2. What is the HyperChem payment term?
T/T in advance
LC at sight
DP at sight
Bank transfer
PayPal
Bitcoin...
Q3. What is HyperChem shipment policy?
Our policy is to strive for the quickest shipment time possible.
For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.
Q4. What is HyperChem shipment term?
By Express
FedEx UPS DHL EMS
Fast: 3-7 days around, high cost, door to door service
By Air
Suitable for more than 50kg
Fast: 3-7 days, hight cost, port to port, professional broker needed
By Sea
Suitable for more than 500kg
Fast: 7-45 days, low cost, port to port, professional broker needed
We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.
Q5. What HyperChem will provide after shipment?
For sample orders:
After shipment is done, an timely email including:
1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice
For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.
Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.
Among them, our key client industrial sectors around the global are:
Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply
HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.
United States
Germany
Portugal
France
United Kingdom
Sweden
Switzerland
India