haloxyfop-P-methyl 108g/l EC 95% TC made in China weed killer herbicide

haloxyfop-P-methyl 108g/l EC 95% TC made in China weed killer herbicide

NOMENCLATURE

haloxyfop-P

IUPAC name (R)-2-[4-(3-chloro-5-trifluoromethyl-2-pyridyloxy)phenoxy]propionic acid  

Chemical Abstracts name (R)-(+)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoic acid  

CAS RN [95977-29-0]  

haloxyfop-P-methyl

IUPAC name methyl (R)-2-[4-(3-chloro-5-trifluoromethyl-2-pyridyloxy)phenoxy]propionate  

Chemical Abstracts name methyl (R)-(+)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoate  

Other names haloxyfop-R  CAS RN [72619-32-0]  EEC no. 406-250-0  Development codes DE-535 (Dow)  

APPLICATIONS

Biochemistry Fatty acid synthesis inhibitor, by inhibition of acetyl CoA carboxylase (ACCase).  Mode of action Haloxyfop-P-methyl is a selective herbicide, absorbed by the foliage and roots, and hydrolysed to haloxyfop-P, which is translocated to meristematic tissues, and inhibits their growth.  Uses Haloxyfop-P-methyl is used post-emergence for control of annual and perennial grasses in sugar beet, fodder beet, oilseed rape, potatoes, leaf vegetables, onions, flax, sunflowers, soya beans, vines, strawberries, and other crops. Applied at 52-104 g a.e./ha. Formulation types EC.  

haloxyfop-P-methyl

Selected products: 'Gallant Super' ()

ANALYSIS

Product analysis by hplc. Residues determined by glc. Details available from .  

MAMMALIAN TOXICOLOGY

haloxyfop-P-methyl

Oral Acute oral LD50 for male rats 300, female rats 623 mg/kg.  Skin and eye Acute percutaneous LD50 for rats >2000 mg/kg. Non-irritant to skin; slightly irritating to eyes (rabbits).  NOEL (2 y) for rats 0.065 mg/kg b.w. daily; no increase in hepatotoxicity.  ADI As haloxyfop.  EC classification Xn; R22| N; R50, R53

ECOTOXICOLOGY

haloxyfop-P

Birds Acute oral LD50 for bobwhite quail 414 mg/kg.  Fish LC50 (96 h) for rainbow trout >50 mg/l.  Daphnia LC50 (48 h) >100 mg/l.  Algae EC50 (96 h) >70 mg/l.  Bees LD50 (48 h, oral and contact) >100 mg/bee.  

haloxyfop-P-methyl

Birds Acute oral LD50 for bobwhite quail 1159 mg/kg.  Fish LC50 (96 h) for rainbow trout 0.7 mg/l.  Daphnia LC50 (48 h) 6.12 mg/l.  Algae EC50 (5 d) 1.72 mg/l.  Bees LD50 (48 h, oral and contact) >100 mg/bee.  Worms LC50 (14 d) 1343 mg/kg.  

ENVIRONMENTAL FATE

haloxyfop-P-methyl

Animals In mammals, rapidly converted to the parent acid and eliminated.  Plants Hydrolysed to haloxyfop, terminal residue haloxyfop, or conjugates.  Soil/Environment DT50 <24 h, forming the parent acid, which is then microbially degraded. Haloxyfop acid degradation approximates to first order kinetics and involves degradation to the pyridinol and other minor metabolites. DT50 9 to 20.5 d, average 14 d (various soil types).