CAS 83-88-5 Riboflavin Vitamin B drugs Food additives: nutritional supplements vitamin

Appearance: Yellow to orange crystalline powder, slightly smelly, slightly bitter taste. Melting point 280℃(decomposition). Soluble in alkaline solution and sodium chloride solution, slightly soluble in water, slightly soluble in ethanol, insoluble in ether and chloroform. The aqueous solution is yellowish-green and the saturated aqueous solution is neutral. Heat resistance, acid resistance is good, in alkaline solution or ultraviolet irradiation is vulnerable to destruction, reducing agents are also unstable. Rats were intraperitoneally injected with LD50560mg/kg and ADI 0-0.5 mg/kg(FAO/WHO, 1994).
Melting point: 290 °C (dec.)(lit.)
Specific rotation: -135 º (c=5, 0.05 M NaOH)
Boiling point: 504.93°C (rough estimate)
Packing density: 100kg/m3
Density: 1.2112 (rough estimate)
Refractive index: -135 ° (C=0.5, JP Method)
Flash point: 9℃
Storage conditions: 2-8°C
Solubility: Very slightly soluble in water, practically insoluble in ethanol (96 per cent). Solutions deteriorate on exposure to light, especially in the presence of alkali. It shows polymorphism (5.9).
Acidity factor: (pKa)1.7(at 25℃)
Form: Powder
Color: Yellow to orange
PH: 5.5-7.2 (0.07g/l, H2O, 20°C)
Odor: (Odor) Slight odor
Acid-base indicator color change ph range: 6
Water solubility: 0.07g /L (20 ºC)
Sensitivity: light sensitive

Use 1
Used to treat riboflavin deficiency, conjunctivitis, nutritional ulcers, systemic dystrophia and other diseases
Use 2
Biochemical research, photocatalyst, nutrient and clinical drug for acrylamide gel polymerization belong to vitamin B group, participate in the metabolism of sugar, fat and protein in the body, maintain normal visual function and promote growth. Clinical for the treatment of lack of vitamin B2 caused by keratitis, slossitis and other diseases.
Use 3
Vitamin B2 is a vitamin that promotes the growth and development of the body and plays an important role in the process of human metabolism. Lack, prone to conjunctivitis, keratitis, glossitis and other diseases. China stipulates that it can be used for table salt, the amount of use is 100 ~ 150mg/kg; The maximum usage in solid drinks is 10 ~ 13mg/kg; The amount used in infant food is 4 to 8mg/kg; The dosage in cereals and their products is 3.0 ~ 5.0mg/kg; The amount used in liquid and milk drinks is 1 ~ 2mg/kg. It can also be used as a yellow colorant.
Use 4
Riboflavin exists in green vegetables, soybeans, rice, wheat, yeast, liver, heart and milk, riboflavin is distributed in various tissues in the body, constituting a coenzyme in the body's complement hydrogenation system, participating in REDOX reaction, and playing the role of transferring hydrogen atoms. When riboflavin is lacking, it will affect biological oxidation, cause metabolic disorders, and cause lesions in the mouth, eyes, external genitalia, such as keratitis, cheilitis, conjunctivitis, scrotis, etc. Riboflavin is mainly used as medicine, food additives and feed additives, in the medicinal aspect, used in complex vitamins or vitamin B2 preparations, but also used as a yellow coloring agent for sugar tablets and capsules. When used as a food additive, on the one hand, it has the effect of strengthening nutrition, and on the other hand, it is also used as a yellow coloring agent. The LD50 of intraperitoneal injection was 560mg/kg.
Use 5
Yellow catalyst for acrylamide gel polymerization. Preparation of tissue medium. Biochemical research. Leptospira culture-medium was prepared in serum test of bacteria.