High Quality 99% Colorless Liquid (1alpha,2beta,4beta)-1-methyl-2,4-bis(methylvinyl)-1-vinylcyclohexane CAS No.:33880-83-0 from YI Hang

Essential information

Molecular formula: C15H24

Molecular weight: 204.35

Physical property

Boiling point: 277.87°C (rough estimate)

Melting point: 

Density: 0.8749

Solubility: Soluble in organic solvents

Refractive index: 1.4935

Odor: Fresh grass scent

EINECS No.: 251-713-0

point of flammability: 132°C

LogP：5.772 (est)

Pharmacological action and application

The pharmacological effects of 1-vinyl-1-methyl-2, 4-bis (propyl-1-ene-2-yl) cyclohexane are mainly reflected in the anti-tumor activity. Studies have shown that 1-vinyl-1-methyl-2, 4-bis (propyl-1-ene-2-yl) cyclohexane can exert anti-tumor effects on a variety of cancer markers, including direct and indirect anti-tumor effects such as inducing tumor cell apoptosis, inhibiting tumor cell proliferation, anti-tumor metastasis and active immune protection. It has been found that 1-vinyl-1-methyl-2, 4-bis (propyl-1-ene-2-yl) cyclohexane can reverse the malignant phenotype of glioblastoma by improving the dryness, differentiation, and epithelial mesenchymal transformation (EMT) of glioblastoma cells. In addition, 1-vinyl-1-methyl-2, 4-bis (prop-1-ene-2-yl) cyclohexane can induce apoptosis through an intrinsic apoptotic pathway mediated by mitochondria, thereby sensitizing chemotherapy. It is worth noting that the antitumor effect of 1-vinyl-1-methyl-2, 4-bis (propyl-1-ene-2-yl) cyclohexane is different from that of traditional chemotherapy drugs in that it has the dual effect of inhibiting the proliferation of Chemicalbook tumor cells and improving immune function. Based on the characteristics of 1-vinyl-1-methyl-2, 4-bis (propyl-1-ene-2-yl) cyclohexane to change or enhance immunogenicity, when combined with chemoradiotherapy, it can prevent leukocyte decline caused by radiotherapy and other chemotherapy drugs, and produce immune protection. In addition, it also has a strong killing effect on drug-resistant tumor cell lines with high expression of multi-drug resistance genes, especially suitable for tumor treatment that has developed tolerance to chemotherapy drugs. It has been reported that 1-vinyl-1-methyl-2, 4-bis (propyl-1-ene-2-yl) cyclohexane can enhance the sensitivity of A549 cells to radiotherapy at a dose of 45mg/kg. In addition, the antitumor effect of 1-vinyl-1-methyl-2, 4-bis (propyl-1-ene-2-yl) cyclohexane was also related to the concentration and duration of the drug. The higher the concentration and the longer the duration of the drug, the apoptosis rate showed an increasing trend. However, when the concentration of the drug exceeded a certain value, the cell necrosis rate also increased correspondingly, and the spontaneous mortality decreased. Therefore, it is necessary to screen the dose concentration according to the population and cancer category to improve its anticancer effect.

Packaging Details: 25 kg/bag or as your requirement.
Port: Tianjin/ Qingdao/ Shanghai, etc.
We can ship the samples by air.
Lead Time: Within 2-3days after receiving the advance payment or original L/C.

XI'AN YI HANG CHEMICAL CO.,LTD was founded in 2002, located in xian City, shannxi, China. We are the high-tech chemical enterprise which specialized in researching, manufacturing and trading for chemical raw materials ,our products widely used in paints, textile, rubber, leather, plastic and so on.

With many years development and operation,we have become the group company for chemical production,we have the owned factory for produce stable quality products with high performance, and the advanced lab to ensure the best quality of each batch products.

We have our strictly quality control in our production, and we have passed ISO9001:2015 Quality Management System Certification and ISO14001 Environment Management System Certification.

Our main products includes Titanium Dioxide, Lithopone, Iron Oxide series, Chrome Oxide Green, Zinc Oxide, Carbon Black, STPP, SHMP, Oxalic Acid, DOP, SLES, and so on.

Q1: Are you manufacturer or trading company?

A1:Manufacturer.

Q2: Can I get some sample?
A2: Yes, usually 10-25g sample for free.

Q3: Is there a discount?
A3: Of course, welcome to contact us. Price would be different based on different quantity. For bulk
quantity, we will have discount for you.

Q4: How long for production and delivery?
A4: Most products we have in stock, sent time:Within 1-3 business days after received payment. Customized products further discussed.

Q5: Do you accept ODM or OEM service?
A5: Yes,we accept ODM and OEM services, ranges: Soft gel, Capsule, Tablet, Sachet, Granule,Private Label service, etc. Please contact us to design your own brand product.

Q6: How to deliver the goods?
A6: ≤50kg ship by FedEx or DHL etc, ≥50kg ship by Air, ≥100kg can be shipped by Sea. If you have special request on delivery, please contact us.

Q7: How to start orders or make payments?
A7:There are two ways for you to confirm order:
1. Proforma invoice with our company bank details will be sent to you once the order confirmed by Email. Pls arrange payment by  TT. Goods will be sent after received payment within 1-3 business days.
2. Trade assurance order will be drafted for you through ALIBABA. Pls confirm and pay through Alibaba. Goods will be sent after  received payment within 1-3 business days.