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GS-441524 Factory direct sales, ready supply

Name: GS-441524 Factory direct sales, ready supply
Brand: COMINGS
SKU: pr2502211171
Price: 99.99 USD
Availability: InStock

53 Inquiries

Unit Price: Get Latest Price 

CAS No.:

1191237-69-0

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

COMINGS

Packaging:

5mg/Bottle

Price valid (until):

2025-06-26

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Wuhan Comings Biotechnology Co., Ltd.

Company Type:

Trader

Location:

China

Payment Terms:

TT against copy of documents,100% TT in advance

Average Lead Time:

15 days

Qualification:

Main Products:

semaglutide,tirzepatide,Liraglutide,Retatrutide,5-amino-1MQ,SLU-PP-332

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Product Description
Seller Information
Inquiry History

Description

Product Detail

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Items	Specifications
Product Name	GS-441524
CAS NO.	1191237-69-0
Purity	99%
Molecular formula	C12H13N5O4
MOQ	1g

What is GS-441524 purpose?
GS-441524 purpose
Remdesivir metabolites. Remdesivir blocks SARS-CoV and MERS-CoV in HAE cells with ECEs both of 74 Nm and showed potent activity in blocking 2019-nCov (coronavirus). Remdesivir, also known as GS-5734, is an antiviral drug and a novel nucleotide analog prodrug. Remdesivir inhibits murine hepatitis virus (MHV) with an EC50 of 30 nM and blocks SARS-CoV and MERS-CoV in HAE cells with an EC50 of 74 nM in HAE cells after 24 h of treatment. GS-5734 inhibits epidemic and zoonotic coronaviruses. It was developed by Gilead Sciences to treat filovirus infections such as Ebola virus disease and Marburg virus.

The packaging of GS-441524
1g,5g,10g,100g

Wuhan Comings Biotechnology Co., Ltd. was established in 2016. Since its establishment, the company has always been committed to making more people healthy, making more people young and happy, and providing customers with high-quality and efficient services.

The company cooperates with biological experts from many universities, adopts modern gene cloning technology and unique purification technology, and strictly controls all aspects. The adipotide we produce are sold well in Europe, Africa, and America, and many customers have given good reviews.

And our company has storage bases in Shenzhen, Shanghai, Qingdao ports to ensure that all goods can arrive safely, on time and quickly.

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ECHEMI Editorial Reference

GS-441524 is a nucleoside analogue that terminates the RNA chain of viral RNA-dependent RNA polymerase. GS-441524 was developed by Gilead Sciences, Inc as part of their research into human RNA virus disease such as Ebola. GS-441524 is a small molecule that exhibits potent antiviral activity against a number of RNA viruses, including the zoonotic severe acute respiratory syndrome (SARS) coronavirus ( Cho et al., 2012).
GS-441524 is a C-nucleoside analog that is (2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile substituted by a 4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl group at position 2. It is the active metabolite of remdesivir and exhibits a broad range of inhibitory activity against various RNA viruses including HCV, parainfluenza and SARS-CoV. It has a role as a drug metabolite, an antiviral agent and an anticoronaviral agent. It is a pyrrolotriazine, a nitrile, a C-nucleoside and an aromatic amine.|GS-441524 is an adenosine nucleotide analog antiviral, similar to [remdesivir]. This molecule was patented in 2009. In vitro studies of GS-441524 have determined it has a higher EC50 than remdesivir against a number of viruses, meaning GS-441524 is less potent. GS-441524 continues to be studied in the treatment of Feline Infectious Peritonitis Virus, a coronavirus that only infects cats.

Basic Info

Product Name:

GS-441524

Other Name:

(2R,3R,4S,5R)-2-(4-Aminopyrrolo(2,1-f)(1,2,4)triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydro-2-furancarbonitrile;GS-441524;GS441524;(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-carbonitrile;GS-441524 solution;EVO984;EVO 984;EVO-984;GS 441524

CAS No.:

1191237-69-0

Molecular Formula:

C12H13N5O4

InChIKeys:

BRDWIEOJOWJCLU-LTGWCKQJSA-N

Molecular Weight:

291.26

Exact Mass:

291.096754

UNII:

1BQK176DT6

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

150

XLogP3:

-1.27552

Density:

1.84±0.1 g/cm3(Predicted)

See More GS-441524 Properties 

Seller Information

Business Type:
Trader

Main Products:
semaglutide,tirzepatide,Liraglutide,Retatrutide,5-amino-1MQ,SLU-PP-332

Location:
No. 1, 19th Floor, Unit 2, Building 5, Southeast Residential Building (Hankou Yujiang Lanting), at the intersection of Hanshi Highway and Fufa South Road, Wuhu Street, Huangpi District, Wuhan City, Hu

Payment Terms:
TT against copy of documents,100% TT in advance

Average lead Time:
15 days

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
11-50

Year of Establishment:
2023

We prospectively allocates international cutting-edge production and testing equipment and environmental protection facilities. The 5 production lines can achieve an annual output of 1000Kg. We to be the best chemical manufacture in China,and will become a trustworthy supplier of chemicals for global customers.
Our main products include peptides, cognitive enhancers, pharmaceutical intermediates, and botanical extracts.
And our main clients cover: pharmaceutical companies, hospitals, laboratories in higher education institutions, and cosmetic companies.
Since its establishment, our company's products have been exported to regions including Europe, the Americas, the Middle East and so on. Our commitment to high product quality and excellent after-sales service has provided customers with a positive experience.
Wuhan Comings Biotechnology Co., Ltd. is looking forward to cooperating with you with professional knowledge, high-quality service and competitive price!

Inquiry History

53 Inquiries

Country	Product	Purchase Quantity	Date Posted
Turkey	GS441524 powder CAS 1191237-69-0 Remdesivir GS-5734 Alprostadil pge	1 PCS	Jan 6, 2026
Bulgaria	Lowest price in the whole network 1191237-69-0 GS-441524	100 BOU	Nov 8, 2023
United States	GS441524 CAS 1191237-69-0 Cat Fip GS441 liquid 20mg 30mg 6ml 8ml 10ml	4 MT	Oct 18, 2023
China	GS 441524	1 KG	Dec 5, 2023
Japan	GS-441524	100 MT	Oct 2, 2026
Italy	Gs-441524	20 MG	Sep 28, 2026
Mexico	Fip Cat Gs-441524 Fipv	1 KG	Jul 3, 2026
Malaysia	Gs-441524	10 MG	Jun 15, 2026
China	GS-441524	1680 MG	May 2, 2026
Poland	GS-441524	100 G	Feb 25, 2026
Poland	GS-441524	1 KG	Feb 25, 2026
Turkey	gs-441524	100 G	Feb 20, 2026
Bangladesh	Gs-441524 fipv	1 MT	Jan 26, 2026
Czech	GS-441524	1000 PCS	Nov 5, 2025
Italy	GS-441524	100 G	Oct 28, 2025
Pakistan	GS441524	1 KG	Aug 5, 2025
Turkey	GS-441524	100.00 G	Jun 30, 2025
Bulgaria	Gs-441524	100 MT	Dec 6, 2024
Pakistan	GS441	10 MT	Nov 28, 2024
Pakistan	GS441524,	1 KG	Sep 4, 2024

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GS-441524 Factory direct sales, ready supply

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