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Tegoprazan 99%

ISO 7 Inquiries

Unit Price: Get Latest Price
CAS No.:

942195-55-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shanghai

Brand:

DIDEU

Packaging:

1Kg/Tin

Price valid (until):

2025-05-03

Company Type:
Manufactory
Location:
China
Qualification:
Main Products:

Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Tegolazan is a potassium competitive acid blocker (P-CAB), which is a new type of acid inhibitor with a novel mechanism of inhibiting acidity. Its mechanism of action is shown in the following figure. Tegolasheng acts on resting or activated H+/K+- ATPase through hydrogen and ionic bonds, thereby inhibiting the conformational changes of the enzyme and preventing it from completing hydrogen potassium exchange, thus exerting an acid suppressing effect.

    Items Specifications
    Appearance White to off-white powder
    Assay, % 98~102.0
    Loss on Drying, % 0.1
    ECHEMI Editorial Reference
    Tegoprazan: a novel potassium-competitive acid blocker.Tegoprazan is a novel potassium-competitive acid blocker (P-CAB) showing promising in vitro and in vivo animal pharmacology activities; clinical studies showed favourable tolerability and safety as well as potent and long-lasting efficacy. P-CABs represent a new class of drugs; they exhibit rapid and effective anti-secretory activity by competitively and reversibly binding with H+/K+-ATPase on the parietal cell. Unlike conventional Proton pump inhibitors (PPIs), tegoprazan offers a rapid onset of action and full effect from the first dose as it can immediately inhibit proton pumps.10 Furthermore, since P-CABs do not require activation in the presence of gastric acid, they can be administered regardless of meals. Therefore, P-CABs are expected to have improved NAB control, overcoming the limitations of current PPIs[1].

    Certificates

    Basic Info
    Product Name:

    Tegoprazan

    Other Name:

    7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-chromen-4-yl]oxy]-N,N,2-trimethyl-3H-benzimidazole-5-carboxamide;CJ 12420;RQ-00000004;RQ-4;1H-Benzimidazole-5-carboxamide, 7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl]oxy]-N,N,2-trimethyl-;7-[[(4S)-5,7-difluoro-3,4-dihydro-2H-1-benzopyran-4-yl]oxy]-N,N,2-trimethyl-1H-benzimidazole-5-carboxamide;Tegoprazan Emixustat HCL Hydrochloride;Tegoprazan

    CAS No.:

    942195-55-3

    Molecular Formula:

    C20H19F2N3O3

    InChIKeys:

    CLIQCDHNPDMGSL-HNNXBMFYSA-N

    Molecular Weight:

    387.38

    Exact Mass:

    387.13944780

    UNII:

    W017G7IF4S

    Color/Form:

    Off-white to light yellow

    Characteristics
    Density:

    1.371±0.06 g/cm3(Predicted)

    Boiling Point:

    596.5±50.0 °C(Predicted)

    PKA:

    9.73±0.30(Predicted)

    Critical Temperature & Pressure:

    Store at -20°C

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Chemical Pesticides,Food Additives,Agrochemicals,Active Pharm Ingredients,Flavors and Fragrances,Chemical Catalyst

    Location:

    https://www.dideu.com/en/

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    Above $100 million

    Total Employees:

    Above 1000

    Year of Establishment:

    2016

    Certifications:

    ISO Certificate,REACH

    Company Profile
    ">Company Profile
  • Inquiry History
    7 Inquiries
    Country Product Purchase Quantity Date Posted
    Pakistan

    Tegoprazan

    1 KG Aug 1, 2024
    Pakistan

    TEGOPRAZAN

    100 KG Dec 9, 2025
    Pakistan

    Tegoprazan

    1 KG Apr 3, 2025
    Pakistan

    TEGOPRAZAN

    1 KG Apr 7, 2026
    Pakistan

    Tegoprazan

    1 MT Dec 5, 2025
    Pakistan

    Tegoprazan

    5 KG Jan 6, 2025
    India

    Tegoprazan

    5 G Feb 13, 2024
    Post an enquiry for this product
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