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API Metformin

Name: API Metformin
Brand: Hyper Chem
SKU: pr2504171562
Price: 3 USD
Availability: InStock

2 Inquiries

Unit Price: Get Latest Price 

CAS No.:

657-24-9

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

Hyper Chem

Packaging:

20kg/Drum 25kg/Drum

Price valid (until):

2025-05-17

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	Metformin
CAS number	657-24-9
Related CAS	1115-70-4 (HCl) ， 657-24-9 (free base) ， 121369-64-0 (glycinate) ， 34461-22-8 ( embonate) 58840-24-7 (orotate) ， 1384526-74-2 (icosapent)
Synonym	Diabetosan; Diabex; Dimethylbiguanide; DMGG; Fluamine; Flumamine; LA 6023; LA6023; LA-6023; Metformin; Metiguanide
Description	Metformin is an AMP-activated protein kinase (AMPK) activator that improves glycemic control by improving insulin sensitivity and decreasing intestinal absorption of glucose. Metformin exerts an anorexiant effect, decreasing caloric intake. Metformin decreases gluconeogenesis (glucose production) in the liver. Metformin inhibits basal secretion from the pituitary gland of growth hormone, adrenocorticotropic hormone, follicle stimulating hormone, and expression of proopiomelanocortin, which in part accounts for its insulin-sensitizing effect with multiple actions on tissues including the liver, skeletal muscle, endothelium, adipose tissue, and the ovaries.
Molecular Formula	C₄H₁₁N₅
Molecular Weight	129.170
Appearance	Solid powder
Quality Standard	USP, EP, BP, CP
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 0 – 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China

Metformin More Info

Metformin, sold under the brand name Glucophage, among others, is the main first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome, and is sometimes used as an off-label adjunct to lessen the risk of metabolic syndrome in people who take antipsychotic medication. It has been shown to inhibit inflammation, and is not associated with weight gain. Metformin is taken by mouth.

Metformin is generally well tolerated. Common adverse effects include diarrhea, nausea, and abdominal pain. It has a small risk of causing low blood sugar. High blood lactic acid level (acidosis) is a concern if the medication is used in overly large doses or prescribed in people with severe kidney problems.

Metformin is a biguanide anti-hyperglycemic agent. It works by decreasing glucose production in the liver, increasing the insulin sensitivity of body tissues, and increasing GDF15 secretion, which reduces appetite and caloric intake.

Metformin was first described in the scientific literature in 1922 by Emil Werner and James Bell. French physician Jean Sterne began the study in humans in the 1950s. It was introduced as a medication in France in 1957. It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2022, it was the second most commonly prescribed medication in the United States, with more than 86 million prescriptions. In Australia, it was one of the top 10 most prescribed medications between 2017 and 2023.

Basic Info

Product Name:

Metformin

Other Name:

Imidodicarbonimidic diamide,N,N-dimethyl-;Biguanide,1,1-dimethyl-;N,N-Dimethylimidodicarbonimidic diamide;N,N-Dimethylbiguanide;N1,N1-Dimethylbiguanide;1,1-Dimethylbiguanide;N,N-Dimethyldiguanide;Flumamine;Metformin;NNDG;Dimethylbiguanide;DMGG;Fluamine;Gliguanid;Haurymelin;Metiguanide;Siofor;N′-Dimethylguanylguanidine;Metphage;Ficonax;Emiphage;Cidophage;Glucofine;Glifor;1-[Amino(dimethylamino)methylidene]guanidine;1-Carbamimidamido-N,N-dimethylmethanimidamide;[[Amino(dimethylamino)methylidene]amino]methanimidamide;Okamet

CAS No.:

657-24-9

Molecular Formula:

C4H11N5

InChIKeys:

InChIKey=XZWYZXLIPXDOLR-UHFFFAOYSA-N

Molecular Weight:

129.16

Exact Mass:

129.16

EC Number:

211-517-8

Categories:

Other Chemical Drugs

Characteristics

PSA:

91.5

XLogP3:

-1.3

Appearance:

Solid

Density:

1.3±0.1 g/cm3

Melting Point:

199-200 °C

Boiling Point:

224.1ºC at 760 mmHg

Flash Point:

58.1±22.6 °C

Refractive Index:

1.576

Water Solubility:

Freely soluble as HCl salt

Storage Conditions:

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature 2 - 8 deg C. Storage class (TRGS 510): Non Combustible Solids. /Metformin hydrochloride/

Vapor Pressure:

7.58X10-5 mm Hg at 25 deg C (est)

Toxicity:

LD50 oral in mouse: 1450mg/kg

PKA:

12.4None

See More Metformin Properties 

Hazard Identification

Classification of the substance or mixture

Not classified.

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)	No symbol.
Signal word	No signal word
Hazard statement(s)	none
Prevention	none
Response	none
Storage	none
Disposal	none

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature 2 - 8 deg C. Storage class (TRGS 510): Non Combustible Solids. Metformin hydrochloride

See More Metformin Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

2 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Metformin	822 KG	Apr 17, 2024
Egypt	Metaformin	50.00 KG	Sep 20, 2023

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