High Quality Sulbactam Pivoxil CAS 69388-79-0 with Fast Delivery

Sulbactam Pivoxil More Info

Sulbactam pivoxil is the orally active prodrug form of sulbactam, a semisynthetic β-lactamase inhibitor . It is formed by esterifying the carboxy group of sulbactam with pivaloyloxymethyl to enhance oral absorption . The compound is also known as Pivsulbactam or CP-47904

Mechanism of Action

Sulbactam pivoxil itself is inactive. After oral administration, its ester bond is cleaved in the body, releasing the active sulbactam . Sulbactam acts as an irreversible, competitive inhibitor of β-lactamase enzymes . It binds to the active site of β-lactamase, blocking the enzyme's ability to hydrolyze and inactivate β-lactam antibiotics (e.g., penicillins, cephalosporins), thereby protecting these antibiotics from bacterial resistance

Applications

Research & Development: Used to study β -lactamase inhibition and to explore oral formulations of sulbactam .

Clinical Potential: As a prodrug with superior absorption, it results in higher serum levels of sulbactam after oral administration compared to sulbactam itself.

Combination Therapy: Sulbactam is used in combination with β -lactam antibiotics like ampicillin, cefoperazone, and piperacillin to treat respiratory, urinary, abdominal, skin, and other infections caused by susceptible bacteria

Safety and Side Effects

Available search results primarily focus on chemical and biological characterization, with limited detailed information on safety profiles. General safety considerations for β -lactamase inhibitors include:

· Potential for hypersensitivity reactions (allergies), especially in patients with penicillin or cephalosporin allergies.

· Gastrointestinal disturbances (diarrhea, nausea) are common with related compounds.

· Drug interactions may occur when combined with other medications.

· As a research chemical, standard laboratory safety precautions (e.g., appropriate handling, personal protective equipment) are recommended

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FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

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Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.

For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express 

FedEx  UPS  DHL  EMS                              

Fast: 3-7 days around, high cost, door to door service

By Air                                       

Suitable for more than 50kg

Fast: 3-7 days, hight cost, port to port, professional broker needed

By Sea

Suitable for more than 500kg     

Fast: 7-45 days, low cost, port to port, professional broker needed

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders:

After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)

2. Packaging photo

3. COA, MSDS, etc

4. Dispatch date & Estimated arriving time

5. Shipping invoice

For commercial orders

A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

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Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.