Oxytocin Acetate hot selling 99% Purity High Quality Weight Loss 5mg 10mg 20mg

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      Oxytocin Acetate, with the CAS number 6233-83-6, is a synthetic nonapeptide derivative widely used in pharmaceutical and research fields. Its chemical formula is C₄₃H₆₆N₁₂O₁₂S₂·C₂H₄O₂, forming a crystalline solid with a molecular weight of 1067.24 g/mol . As the acetate salt of oxytocin, it retains the biological activity while enhancing stability and solubility in aqueous solutions.

Production Process:

      Oxytocin Acetate is primarily synthesized via solid-phase peptide synthesis (SPPS), involving Fmoc or Boc protection strategies to sequentially assemble the nine amino acid residues. The formation of the characteristic disulfide bridge between two cysteine residues is critical, typically achieved through oxidative methods like air oxidation or DMSO treatment under controlled pH conditions (pH 8-9) . Post-synthesis purification employs HPLC to achieve ≥98% purity, ensuring minimal impurities .

Applications:

      In medicine, it is used to control postpartum hemorrhage, and facilitate lactation by promoting mammary gland contraction . In research, Oxytocin Acetate is vital for studying social behavior, stress responses, and neuroendocrine mechanisms. Animal studies demonstrate its role in regulating body temperature and enhancing social interactions, such as increased sniffing behavior in rats at doses of 0.1-0.3 mg/kg .

Quality Standards:

      Complying with international pharmacopeia requirements (e.g., USP, EP), the product undergoes rigorous testing for purity, moisture content (<10%), and related substances. The HPLC method is standard for both content determination and impurity profiling .

Storage & Handling:

      Store at -20°C in airtight containers to maintain stability. Avoid exposure to light and moisture. As a hazardous substance (UN 2811, Class 6.1), it requires cautious handling, with strict adherence to laboratory safety protocols to prevent inhalation or skin contact .

Oxytocin Acetate remains a cornerstone in obstetrics and biomedical research, balancing therapeutic efficacy with precise synthetic control.

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