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Cheap Price High Quality Liranaftate CAS 88678-31-3 Global Warehouse

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CAS No.:

88678-31-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

Shang Hai

Brand:

KDG

Packaging:

1KG/BAG

Price valid (until):

2025-05-15

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Hubei KDG Web Science&Technology Co.,Ltd

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Peptide,API,HCG,Amino Acids,Plant Extract,Vitamin

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Product Description
Seller Information

Description

Product Detail

Liranaftate is a topical antifungal agent primarily used to treat skin infections caused by fungi, such as athlete's foot, jock itch, and ringworm. It works by inhibiting the enzyme squalene epoxidase, which is crucial for the synthesis of ergosterol, a key component of fungal cell membranes. By disrupting this enzyme, Liranaftate leads to increased membrane permeability and cell death in fungal cells. This unique mechanism of action makes it effective against various dermatophytes and provides a safer alternative for patients with resistance to other antifungal treatments.

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ECHEMI Editorial Reference

Liranaftate is a squalene epoxidase inhibitor with anti-fungicidal activities. Target: AntifungalLiranaftate showed excellent fungistatic activity against the conidia of T. rubrum. For each of these agents, the MIC after 14 days of contact was 0.009 g/ml. The liranaftate-induced decrease in the MCC occurred from 9 days onwards; MCC at 14 days was 0.039 g/ml [1]. In time-kill studies, liranaftate showed the greatest decrease to a below detection limit in viable counts of T rubrum. The deg
Liranaftate is a member of tetralins.|Liranaftate is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is essential for cell membrane integrity. By preventing ergosterol synthesis and causing accumulation of squalene, this agent increases cell membrane permeability, cell leakage and eventually cell lysis.

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Basic Info

Product Name:

Liranaftate

Other Name:

Carbamothioic acid,N-(6-methoxy-2-pyridinyl)-N-methyl-,O-(5,6,7,8-tetrahydro-2-naphthalenyl) ester;Carbamothioic acid,(6-methoxy-2-pyridinyl)methyl-,O-(5,6,7,8-tetrahydro-2-naphthalenyl) ester;Piritetrate;Liranaftate;M 732;O-5,6,7,8-Tetrahydro-2-naphthyl 6-methoxy-2-pyridyl(methyl)thiocarbamate;O-(5,6,7,8-Tetrahydro-2-naphthyl) N-(6-methoxy-2-pyridyl)-N-methylthiocarbamate;Zefnart

CAS No.:

88678-31-3

Molecular Formula:

C18H20N2O2S

InChIKeys:

InChIKey=VPHPQNGOVQYUMG-UHFFFAOYSA-N

Molecular Weight:

328.43

Exact Mass:

328.43

EC Number:

-0

UNII:

5253IGO5X3

DSSTox ID:

DTXSID6046470

NCI Thesaurus Code:

C66019

Categories:

Other Chemical Drugs

Characteristics

PSA:

66.7

XLogP3:

4.9

Appearance:

white crystalline solid

Density:

1.2±0.1 g/cm3

Melting Point:

98.5-99.5°C

Boiling Point:

462.5°C at 760 mmHg

Flash Point:

233.5±31.5 °C

Refractive Index:

1.642

Storage Conditions:

-20°C Freezer

See More Liranaftate Properties 

Hazard Identification

Classification of the substance or mixture

Skin irritation, Category 2

Skin sensitization, Category 1

Eye irritation, Category 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P333+P317 If skin irritation or rash occurs: Get medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Liranaftate Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Peptide,API,HCG,Amino Acids,Plant Extract,Vitamin

Location:
Room H0413, Building 1, No. 58, Guanggu Avenue, East Lake New Technology Development,Wuhan

Year of Establishment:
2020
Country Product Purchase Quantity Date Posted

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Cheap Price High Quality Liranaftate CAS 88678-31-3 Global Warehouse

Product Description

Seller Information

Classification of the substance or mixture

GHS label elements, including precautionary statements

Other hazards which do not result in classification

Precautions for safe handling

Conditions for safe storage, including any incompatibilities

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