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Panabinostat

2 Inquiries

Unit Price: Get Latest Price
CAS No.:

404950-80-7

Content:

98%

Port:

shanghai

Packaging:

1g/bottle

Price valid (until):

2025-01-08

Company Type:
Trader
Location:
China
Qualification:
Main Products:

13-Dimethyladamantane,1-Bromo-35-dimethyladamantane,perhydroacenaphthylene,4-[1,1-bis(4-hydroxyphenyl)ethyl]phenol,CYCLOBUTANE-1,2-DICARBOXYLIC ACID DIMETHYL ESTER, TRANS

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Panobinostat (LBH-589, trade name Farydak FAYR-ah-dak) is a drug developed by Novartis for the treatment of various cancers. It is a hydroxamic acid and acts as a non-selective histone deacetylase inhibitor (pan-HDAC inhibitor).
    On 23 February 2015 it received FDA accelerated approval for use in patients with multiple myeloma who had received at least 2 previous treatments, including bortezomib and an immunomodulatory agent.

    Basic Info
    Product Name:

    Panobinostat

    Other Name:

    2-Propenamide,N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-,(2E)-;(2E)-N-Hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide;Panobinostat;LBH 589;Farydak;NVP-LBH 589;NVP LBH 589;944726-21-0

    CAS No.:

    404950-80-7

    Molecular Formula:

    C21H23N3O2

    InChIKeys:

    InChIKey=FPOHNWQLNRZRFC-ZHACJKMWSA-N

    Molecular Weight:

    349.42622

    Exact Mass:

    349.43

    EC Number:

    1592732-453-0

    HScode:

    2933990090

    Characteristics
    PSA:

    77.2

    XLogP3:

    3

    Appearance:

    Yellow solid

    Density:

    1.2±0.1 g/cm3

    Melting Point:

    114-117°C

    Refractive Index:

    1.683

    Storage Conditions:

    -20°C Freezer, Under Inert Atmosphere

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 3, Oral

    Skin irritation, Category 2

    Serious eye damage, Category 1

    Acute toxicity - Category 3, Inhalation

    Reproductive toxicity, Category 1B

    Specific target organ toxicity – repeated exposure, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H301+H331 Toxic if swallowed or if inhaled

    H315 Causes skin irritation

    H318 Causes serious eye damage

    H360 May damage fertility or the unborn child

    H373 May cause damage to organs through prolonged or repeated exposure

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    P203 Obtain, read and follow all safety instructions before use.

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P354+P338 IF IN EYES: Immediately rinse with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P317 Get medical help.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P316 Get emergency medical help immediately.

    P318 IF exposed or concerned, get medical advice.

    P319 Get medical help if you feel unwell.

    Storage

    P405 Store locked up.

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    13-Dimethyladamantane,1-Bromo-35-dimethyladamantane,perhydroacenaphthylene,4-[1,1-bis(4-hydroxyphenyl)ethyl]phenol,CYCLOBUTANE-1,2-DICARBOXYLIC ACID DIMETHYL ESTER, TRANS

    Location:

    Room 1623,Building A, ZhongqiaoCenter,Goverment District,Hefei city,Anhui Province,China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    5-10

    Year of Establishment:

    2019

  • Inquiry History
    2 Inquiries
    Country Product Purchase Quantity Date Posted
    Brazil

    Panabinostat

    1 G May 24, 2025
    United Kingdom

    Panobinostat

    1 G May 26, 2026
    Post an enquiry for this product
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