Hot selling 99% Carboplatin 41575-94-4

Carboplatin More Info

Carboplatin (CAS: 41575-94-4) is a platinum-based chemotherapy drug widely used in the treatment of various cancers, including ovarian, lung, and head/neck malignancies. It is a second-generation analog of cisplatin, designed to reduce nephrotoxicity while maintaining antitumor efficacy. Carboplatin works by forming DNA cross-links, ultimately inhibiting cancer cell replication. It is typically administered intravenously in clinical settings under strict medical supervision.

Pharmacological Action

Carboplatin exerts its cytotoxic effects by binding to DNA and forming intra- and inter-strand cross-links, which disrupt DNA synthesis and transcription, leading to apoptosis in rapidly dividing cancer cells. Unlike cisplatin, carboplatin is less reactive and more stable, resulting in a milder toxicity profile. Its activity is cell-cycle nonspecific, making it effective against a broad range of tumors. The drug is primarily excreted renally, requiring dose adjustments in patients with impaired kidney function.

Usage Guidelines

Carboplatin is administered intravenously, with dosing calculated based on body surface area (BSA) or glomerular filtration rate (GFR) using the Calvert formula. Treatment cycles are usually repeated every 3–4 weeks, depending on the cancer type and patient response. Premedication with antiemetics is recommended to reduce nausea and vomiting. Strict monitoring of blood counts (e.g., neutrophils, platelets) and renal function is essential to manage myelosuppression and nephrotoxicity risks.

Adverse Effects

Common side effects include myelosuppression (anemia, thrombocytopenia, neutropenia), nausea/vomiting, and fatigue. Less frequent but severe reactions may involve allergic responses, peripheral neuropathy, or ototoxicity. Unlike cisplatin, carboplatin has lower risks of nephrotoxicity and neurotoxicity but requires vigilance for hematologic toxicity. Dose adjustments or discontinuation may be necessary in cases of severe adverse reactions.

FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

Bank transfer

PayPal

Bitcoin...

Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
FedEx  UPS  DHL  EMS                               
Fast: 3-7 days around, high cost, door to door service

By Air                                        
Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

By Sea
Suitable for more than 500kg      
Fast: 7-45 days, low cost, port to port, professional broker needed 

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.