100% Ciclopirox ethanolamine 41621-49-2

Ciclopirox ethanolamine More Info

Ciclopirox ethanolamine presents as a white to slightly yellowish crystalline powder with a faint characteristic odor. It demonstrates excellent solubility in water,  glycol but shows limited solubility in nonpolar organic solvents. The compound remains stable under normal storage conditions (room temperature, protected from light and moisture) but may degrade when exposed to strong acids, bases, or oxidizing agents. Its crystalline structure exhibits a melting point range between 130-135°C and shows no  transformations under standard conditions.

Introduction

This synthetic antifungal agent represents a hydroxypyridone derivative with broad-spectrum antimicrobial activity. Unlike typical azole antifungals, it exhibits a unique mechanism of action involving chelation of polyvalent cations, disrupting essential fungal metabolic processes. The salt formulation enhances water solubility while maintaining the parent compound's potent antifungal properties. Clinical studies demonstrate efficacy against dermatophytes, yeasts, and molds, with additional antibacterial and anti-inflammatory effects observed at therapeutic concentrations.

Source

Ciclopirox ethanolamine is exclusively produced through controlled chemical synthesis in GMP-certified facilities. The manufacturing process involves multiple purification steps including crystallization and chromatography to achieve pharmaceutical-grade purity (>99%). Commercial production batches undergo rigorous quality control testing for identity, potency, and absence of harmful impurities. The compound is available in bulk quantities for pharmaceutical formulations and in smaller quantities for research purposes from specialized chemical suppliers.

Uses

• Treatment of superficial fungal infections (onychomycosis, tinea pedis, candidiasis)

• Management of seborrheic dermatitis and dandruff in medicated shampoos

• Preservation of cosmetic products against microbial contamination

• Component in topical formulations for mixed fungal-bacterial skin infections

• Investigational use in wound care products for its antimicrobial properties

Applications

Therapeutic:

Nail lacquers for onychomycosis treatment (typically 8% w/v)

Creams/lotions for cutaneous fungal infections (0.5-1% concentrations)

Shampoos for scalp conditions (1-1.5% formulations)

Non-therapeutic:

Preservative in personal care products

Laboratory antifungal agent in microbiological studies

Veterinary dermatological preparations

Research:

Studies of novel antimicrobial mechanisms

Development of combination therapies

Investigation of biofilm disruption properties

Precautions

Handling:

Use appropriate PPE (nitrile gloves, safety goggles) when handling powder form

Avoid generating dust aerosols during weighing procedures

Implement proper ventilation in processing areas

Storage:

Maintain in original tightly sealed containers at 15-25°C

Protect from moisture and direct sunlight

Separate from strong acids/bases and oxidizing agents

Clinical:

For external use only; avoid contact with eyes/mucous membranes

Discontinue if irritation or hypersensitivity occurs

Not recommended for children under 10 years without medical supervision

Environmental:

Prevent release into waterways or sewage systems

Dispose of waste according to local hazardous material regulations

Regulatory:

Comply with regional pharmaceutical ingredient regulations

Maintain proper documentation for pharmaceutical applications

FAQ

Q1. Can I get a free sample?

We can send you a samll free sample, and you only need to pay for the shipping cost.

Q2. What is the HyperChem payment term?

T/T in advance
LC at sight
DP at sight

Bank transfer

PayPal

Bitcoin...

Q3. What is HyperChem shipment policy?

Our policy is to strive for the quickest shipment time possible.

For ready stock samples, they are usually shipped within 3 working days after payment received.
For non-ready stock, please contact HyperChem sales team to negotiate.

Q4. What is HyperChem shipment term?

By Express  
FedEx  UPS  DHL  EMS                               
Fast: 3-7 days around, high cost, door to door service

By Air                                        
Suitable for more than 50kg 
Fast: 3-7 days, hight cost, port to port, professional broker needed 

By Sea
Suitable for more than 500kg      
Fast: 7-45 days, low cost, port to port, professional broker needed 

We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.

Q5. What HyperChem will provide after shipment?

For sample orders: 
After shipment is done, an timely email including:

1. Track details (Fedex /TNT/DHL/EMS Track number)
2. Packaging photo
3. COA, MSDS, etc
4. Dispatch date & Estimated arriving time
5. Shipping invoice

For commercial orders
A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.

Company Profile

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.

Among them, our key client industrial sectors around the global are:

Pharmaceuticals
Nutrition Ingredients/ Dietary supplements
Cosmetic Ingredients
Food Ingredients
Veterinary API
Agriculture fertilizer
Custom Synthesis lab supply

HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.