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factory supply Apixaban Intermediate Apixaban poweder

20 Inquiries

Unit Price:

$0.1/MT FOB

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CAS No.:

503612-47-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

qingdao

Brand:

Packaging:

25kg/drum

Price valid (until):

2026-12-31

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NATURE INDUSTRIAL LIMITED

Company Type:

Trader

Location:

Hongkong, China

Qualification:

Main Products:

Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

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Product Description
Seller Information
Inquiry History

Description

Factory Price 99% Apixaban API Manufacturer CAS 503612-47-3

Apixaban is an anticoagulant used to reduce the risk of stroke and systemic embolism in patients with non valvular atrial fibrillation.
A key component in helping our customers be first to market is a responsive supply chain. We achieve this by making sure that all our facilities are operating efficiently and to the latest standards of quality, safety, and productivity. A strong interconnect between business and factories allows for a quick reaction to dynamic market changes, so that we can avert shortages and meet sudden surges in demand.
Apixaban is a selective inhibitor of FXa. It does not require antithrombin III for antithrombotic activity. Apixaban inhibits free and clot-bound FXa, and prothrombinase activity. Apixaban has no direct effect on platelet aggregation, but indirectly inhibits platelet aggregation induced by thrombin. By inhibiting FXa, apixaban decreases thrombin generation and thrombus development

Specification of Analysis

Product name	Apixaban
Items	Standards	Results
Appearance	White to off-white solid powder	Complies
Identification	By HNMR	Complies
Identification	By HPLC	Complies
Loss on Drying	≤ 0.50%	0.10%
Heavy Metals	≤ 20ppm	Complies
Residue on Ignition	≤ 0.10%	0.08%
Related Substances	Any single impurity: ≤0.10%	0.05%
Related Substances	Total impurities: ≤0.50%	0.10%
HPLC	≥ 99.5%	99.90%
Assay(HPLC basis on drying)	98.0%~102.0%	99.88%
Reference Standard	In-house Standard
Conclusion	The product complied to In-house standard.
Storage	Preserve in tight,light-resistant containers in a cool place

◼ Superior Efficacy
▸ 21% risk reduction in stroke vs. warfarin (ARISTOTLE trial)
▸ 50% lower major bleeding rates in orthopedic surgeries

◼ Logistics Advantage
▸ Temperature-stable formulation (25°C/77°F ambient storage)
▸ Multilingual packaging compliant with international GMP

◼ Regulatory Excellence
▸ WHO Essential Medicines List (2019) inclusion
▸ Recipient of 7 international pharmaceutical innovation awards

"From Munich to Melbourne, Apixaban protects 2.3 million patients annually" - 2024 Global Anticoagulation Report

Available in:
• 2.5mg & 5mg film-coated tablets
• Hospital/clinic bulk procurement programs
• Customized blister pack configurations

Export Documentation Ready:
• Certificate of Pharmaceutical Product (CPP)
• WHO-GMP compliance statements
• Full dossier support for new market registration

We also supply Apixaban intermediates, welcome to send enquiry.

Shop Pharmaceutical Pure Apixaban Wholesale High Quality Apixaban powder-Detailed Image 1

ECHEMI Editorial Reference

Apixaban is a highly selective, reversible inhibitor of Factor Xa with Ki of 0.08 nM and 0.17 nM in human and rabbit, respectively.

Basic Info

Product Name:

Apixaban

Other Name:

1H-Pyrazolo[3,4-c]pyridine-3-carboxamide,4,5,6,7-tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-;4,5,6,7-Tetrahydro-1-(4-methoxyphenyl)-7-oxo-6-[4-(2-oxo-1-piperidinyl)phenyl]-1H-pyrazolo[3,4-c]pyridine-3-carboxamide;1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid amide;BMS 562247-01;Apixaban;Eliquis;1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide;1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxamide;1-(4-Methoxyphenyl)-7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl]-1H,4H,5H,6H,7H-pyrazolo[3,4-c]pyridine-3-carboxamide

CAS No.:

503612-47-3

Molecular Formula:

C25H25N5O4

InChIKeys:

InChIKey=QNZCBYKSOIHPEH-UHFFFAOYSA-N

Molecular Weight:

459.504

Exact Mass:

459.50

Categories:

Other Chemical Drugs

Characteristics

PSA:

111

XLogP3:

2.2

Density:

1.42

Boiling Point:

770.468ºC at 760 mmHg

Flash Point:

419.8±32.9 °C

Refractive Index:

1.705

Water Solubility:

Aqueous solubility: 40-50 μg/ml in 0.9% saline solutionAqueous solubility across the physiological pH range is approximately 0.04 mg/L

Storage Conditions:

Store at 20 deg C to 25 deg C (68 deg F-77 deg F); excursions permitted between 15 deg C and 30 deg C (59 deg F-86 deg F).

Vapor Pressure:

4.29X10-18 mm Hg at 25 deg C (est)

See More Apixaban Properties 

Hazard Identification

Classification of the substance or mixture

Specific target organ toxicity â repeated exposure, Category 1

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H372 Causes damage to organs through prolonged or repeated exposure
Prevention	P260 Do not breathe dust/fume/gas/mist/vapours/spray. P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product.
Response	P319 Get medical help if you feel unwell.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Apixaban Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

Location:
Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7

Total Annual Revenue:
$50 million-$100 million

Total Employees:
51-100

Year of Establishment:
2012

We have more than 10 years experience in the pharmacy filed. Mainly manufactures pharmaceutical APIs,Pharmaceutical intermediate and Cosmetic raw material. Owing to the good quality and competitive price, we have a very good reputation in China's pharmaceutical circles.

In the principle of "Quality Oriented", Jianfeng passed the certification of ISO9001:2008 Quality Management System.

Our products are based on bulk, high volume, wholesale price, third party testing, certificate reporting, and bring high quality ingredients to many domestic and overseas enterprises.

"Honesty, practicality, innovation, development" are our values. Jianfeng would like to cooperate with you with high quality products and competitive price.

Inquiry History

20 Inquiries

Country	Product	Purchase Quantity	Date Posted
India	Apixaban	50.00 KG	May 29, 2025
India	Apixaban	20.00 KG	May 27, 2025
India	Apixaban	20.00 KG	May 27, 2025
India	Apixaban	40.00 KG	May 27, 2025
India	Apixaban	1 MT	Aug 12, 2026
Italy	Apixaban	50.00 KG	May 25, 2025
India	APIXABAN	1.00 KG	Mar 25, 2025
South Korea	Apixaban	100 KG	Jan 25, 2024
Brazil	Apixaban for wholesale	100 G	Oct 25, 2023
Bangladesh	Apixaban	300.00 KG	May 30, 2025
India	Apixaban	100.00 KG	Nov 11, 2023
India	Apixaban	10 G	Jun 2, 2026
India	Apixaban	260.00 KG	May 28, 2026
India	Apixaban	100 KG	Dec 23, 2025
India	Apixaban	5 G	Jul 4, 2025
India	ISOPROPYL ALCOHOL	20.00 KG	May 27, 2025
India	Methanol	50.00 KG	May 28, 2025
India	Cyclopentane	40.00 KG	May 28, 2025
Belgium	Silicon dioxide	100.00 KG	Jun 5, 2025
Belgium	Linagliptin API	200.00 KG	Jun 5, 2025

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