AZOCASEIN 102110-74-7

More Info

AZOCASEIN (CAS 102110-74-7) is a modified casein derivative, chemically altered by the introduction of an azo group, which enhances its utility as a substrate for enzymatic assays. This orange-red, water-soluble compound is widely used in biochemical research due to its ability to undergo proteolytic cleavage, producing detectable color changes. It is synthesized through the diazotization of casein, ensuring consistent reactivity and stability. AZOCASEIN serves as a critical tool in studying protease activity, particularly in applications requiring high sensitivity and specificity.

Applications and Key Uses

AZOCASEIN is primarily employed as a substrate for measuring protease and peptidase activity in both research and industrial settings. It is commonly used in enzyme kinetics studies, quality control of proteolytic enzymes, and screening for microbial or mammalian protease inhibitors. Additionally, it finds applications in food science (e.g., assessing protein degradation in dairy products) and pharmaceutical development (e.g., evaluating drug candidates targeting proteases). Its colorimetric properties make it suitable for high-throughput screening (HTS) systems, facilitating rapid and efficient analysis.

Market and Industry Demand

The demand for AZOCASEIN is driven by its essential role in life sciences, particularly in academic research, biotechnology, and pharmaceutical development. North America and Europe dominate the market due to their advanced R&D infrastructure, while emerging economies in Asia-Pacific are witnessing growth due to increasing investments in biomedical research. The compound’s application in drug discovery and industrial enzyme production further supports its steady market expansion. Innovations in assay technologies and the rising focus on protease-targeted therapies are expected to sustain long-term demand.

Handling and Safety Considerations

While AZOCASEIN is not classified as highly hazardous, standard laboratory precautions should be followed. Avoid inhalation of dust and direct skin contact by using appropriate personal protective equipment (PPE), including gloves and safety goggles. Store the compound in a cool, dry place, protected from light to maintain stability. Spills should be contained and cleaned promptly with proper disposal in accordance with local regulations. Always consult the Safety Data Sheet (SDS) for detailed handling, storage, and emergency measures.

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