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N-Methyl-2-pyrrolidone(NMP),872-50-4

31 Inquiries

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CAS No.:

872-50-4

Port:

Shang hai

Packaging:

25kg/drum

Price valid (until):

2025-08-26

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PROVCHEM

Company Type:

Manufactory

Location:

China

Qualification:

Main Products:

Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate

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Product Description
Seller Information
Inquiry History

Description

Product Detail

N-Methyl-2-pyrrolidinone (NMP) has a molecular formula of C5H9NO, and it is a colorless to light yellow transparent liquid with a slight ammonia odor. Its boiling point is 204℃, flash point is 91℃, chroma HaZen≤25, refractive index N20D 1.468-1.471, density is 1.032-1.035. It is miscible in water at any ratio, it is soluble in ethanol, acetone, esters, halogenated hydrocarbons, aromatic hydrocarbons and other organic solvents, and it can completely mix with practically all solvents. It is stron

N-methyl-2-pyrrolidone appears as a clear colorless liquid with a "fishlike" odor. Denser than water. Flash point 199°F. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion.|Liquid|COLOURLESS HYGROSCOPIC LIQUID WITH CHARACTERISTIC ODOUR.|A clear colorless liquid with a fish-like odor.

N-methyl-2-pyrrolidone appears as a clear colorless liquid with a "fishlike" odor. Denser than water. Flash point 199°F. Contact may irritate skin, eyes and mucous membranes. May be toxic by ingestion.|N-methylpyrrolidin-2-one is a member of the class of pyrrolidine-2-ones that is pyrrolidin-2-one in which the hydrogen attached to the nitrogen is replaced by a methyl group. It has a role as a polar aprotic solvent. It is a N-alkylpyrrolidine, a lactam and a member of pyrrolidin-2-ones.|N Methyl Pyrrolidone is under investigation for the treatment of Multiple Myeloma.

Items	Specifications
Appearance	Colorless transparent liquid
Melting Point	-25 °C
Water Solubility	H2O: >=10 g/100 mL at 20 ºC

N-Methyl-2-pyrrolidone Use and Manufacturing

Methods of Manufacturing

Large-scale production of NMP /N-methyl-2-pyrrolidone/ is predominantly carried out by reacting gamma-butyrolactone with an excess of pure or aqueous methylamine in a high-pressure tube reactor (6-12 MPa). The reaction is exothermic and often run under adiabatic conditions with reactor temperatures in the range of 250-400 °C. The resulting product mixture is decompressed and distilled. The NMP yield is normally more than 97%.|NMP /N-methyl-2-pyrrolidone/ can also be produced by hydrogenation of N-hydroxymethyl-2-pyrrolidone or by reaction of acrylonitrile with methylamine in the presence of a peroxide radical initiator.|... Hydrogenation of N-methylsuccinimide or mixtures of maleic or succinic anhydride and methylamine.|High-pressure synthesis from acetylene and formaldehyde.

Uses

It is an excellent solvent, widely used as an extractant for aromatic extraction, lubricating oil refining, acetylene concentration, synthesis gas desulfurization, etc. It is also used for industrial cleaning and other purposes. N-methylpyrrolidone is an excellent extraction solvent. It is widely used as an extractant in the process of aromatics extraction, acetylene concentration, butadiene separation and synthesis gas desulfurization. It is also a solvent in the production of pesticides, engineering plastics, coatings, synthetic fibers, integrated circuits, etc. Industrial detergents, dispersants, dyes, lubricants antifreeze, etc. The product has low toxicity, and the oral LD50 for rats is 7ml/kg. It is widely used in solvents such as high-grade lubricating oil refining, polymer synthesis, insulating materials, pesticides, pigments and cleaning agents. Organic Synthesis. Used in aromatic extraction, purification of acetylene, olefin, and diolefin; used in polymer solvent and polymerization medium, such as engineering plastics such as polyamide, polyimide, polyphenylene sulfide, and aramid fiber

Additive

Adhesives and sealants

Basic Info

Product Name:

N-Methyl-2-pyrrolidone

Other Name:

2-Pyrrolidinone,1-methyl-;2-Pyrrolidone,1-methyl-;1-Methyl-2-pyrrolidinone;N-Methylpyrrolidinone;1-Methyl-5-pyrrolidinone;NMP;N-Methyl-2-pyrrolidone;N-Methyl-α-pyrrolidinone;N-Methyl-α-pyrrolidone;N-Methyl-γ-butyrolactam;N-Methyl-2-pyrrolidinone;N-Methylpyrrolidone;M-Pyrol;1-Methylazacyclopentan-2-one;1-Methyl-2-pyrrolidone;Pyrol M;N-Methylpyrrolidone;AgsolEx 1;N 0131;Microposit 2001;N-Methyl-2-ketopyrrolidine;N-Methylbutyrolactam;Pharmasolve;SL 1332;NSC 4594;N-Methylpyrrolidine-2-one;M 0418;EKOS 1;NMP 1165;26138-58-9;53774-35-9;57762-46-6

CAS No.:

872-50-4

Molecular Formula:

C5H9NO

InChIKeys:

InChIKey=SECXISVLQFMRJM-UHFFFAOYSA-N

Molecular Weight:

99.13110

Exact Mass:

99.13

EC Number:

212-828-1

UNII:

JR9CE63FPM

ICSC Number:

0513

NSC Number:

4594

UN Number:

1993

DSSTox ID:

DTXSID6020856

Color/Form:

Clear liquid

HScode:

2933990090

Categories:

Dissolving Agent

Characteristics

PSA:

20.31000

XLogP3:

0.17650

Appearance:

Density:

1.027 g/cm³ @ Temp: 25 °C

Melting Point:

-25 °C

Boiling Point:

202 °C @ Press: 760 Torr

Flash Point:

91ºC

Refractive Index:

n20/D 1.479

Water Solubility:

H2O: >=10 g/100 mL at 20 ºC

Storage Conditions:

2-8ºC

Vapor Pressure:

0.29 mm Hg ( 20 °C)

Vapor Density:

3.4 (vs air)

Toxicity:

LD50 orally in Rabbit: 3598 mg/kg LD50 dermal Rabbit 8000 mg/kg

Explosive limit:

vol% in air: 1.3.5

Odor:

Mild amine odor

PH:

pH = 7.7-8

Henrys Law Constant:

3.20e-09 atm-m3/mole

Experimental Properties:

Dipole moment at 25 °C: 4.09 debye; Dielectric constant at 25 °C: 32.3|Hydroxy radical rate constant = 7.4X10-11 cu cm/molecule-sec at 25 °C

Air and Water Reactions:

Soluble in water.

Reactive Group:

Amides and Imides

Reactivity Profile:

This amine is a very mild chemical base. It does tend to neutralize acids to form salts plus water. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.

Autoignition Temperature:

655 °F (346 °C)|245 °C

Heat of Combustion:

719 kcal/mol

Heat of Vaporization:

127.3 kcal/Kg

Critical Temperature & Pressure:

Critical temperature = 451 °C; Critical pressure = 4.78 MPa

See More N-Methyl-2-pyrrolidone Properties 

Hazard Identification

Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity â single exposure, Category 3

Reproductive toxicity, Category 1B

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Danger
Hazard statement(s)	H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P203 Obtain, read and follow all safety instructions before use.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P319 Get medical help if you feel unwell. P318 IF exposed or concerned, get medical advice.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

NO open flames. Above 86Â°C use a closed system and ventilation. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Dry. Ventilation along the floor. Separated from strong oxidants, strong acids, strong bases, copper and plastics.Small quantities can be stored in polyethylene, polypropylene, or clear glass bottles.

See More N-Methyl-2-pyrrolidone Safety Data Sheet 

Seller Information

Business Type:
Manufactory

Main Products:
Agrochemicals,Daily Chemicals,Catalysts & Chemical Auxiliary Agents,Extract,Inorganic Chemicals,Organic Intermediate

Location:
9F/TOWER B DANING MUSIC PLAZA NO.777, WANRONG ROAD JINGAN, DISTRICT, SHANGHAI, R.P. CHINA

Payment Terms:
TT against copy of documents,D/P,L/C,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
14

Total Annual Revenue:
$2.5 million-$5 million

Total Employees:
5-10

Year of Establishment:
2022

Inquiry History

31 Inquiries

Country	Product	Purchase Quantity	Date Posted
Switzerland	Lowest price CAS 872-50-4 N-Methylpyrrolidone 99.5% white powder MF	150 MT	Jul 25, 2023
Malaysia	N-Methyl-2-pyrrolidone	120 TON	Aug 23, 2024
South Africa	NMP	3000 KG	Aug 10, 2023
Morocco	N-methyl-2-pyrrolidone	14 MT	Apr 2, 2026
South Korea	N-Methyl-2-Pyrrolidone	700 KG	Feb 22, 2024
Paraguay	N-METHYL-2-PYRROLIDONE	3000 KG	Jun 1, 2026
United States	N-Methyl-2-pyrrolidone	38 MT	May 23, 2026
Paraguay	N-METHYL-2-PYRROLIDONE	3000 KG	Apr 27, 2026
Paraguay	N-Methil-2-pyrrolidone	1000 KG	Feb 25, 2026
India	n methyl-2 pyrrolidone	10 MT	Feb 25, 2026
Egypt	N-Methyl-2 Pyrrolidone	2400 KG	Jan 27, 2026
Malaysia	N-Methyl-2-pyrrolidone	5000 KG	Jul 25, 2025
India	N-Methylpyrrolidone	1.00 MT	Dec 13, 2024
United Arab Emirates	N-METHYL PYRROLIDONE	12000 KG	Nov 18, 2024
India	NMP N-Methyl-2- pyrrolidone	100 MT	Sep 24, 2024
Russia	N-methyl-ɑ-pyrrolidone	1000 L	Oct 9, 2023
Russia	N-methyl-ɑ-pyrrolidone	1000 KG	Oct 8, 2023
Malaysia	N-Methyl pyrrolidone packed in Drum	234 MT	Sep 6, 2023
India	Nmp	1 20' Fcl	Aug 10, 2023
India	N-methyl pyrrolidone	1.00 KG	May 9, 2026

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