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Home > Pharmaceutical Intermediates > Antispasticity Agents > 5-Aminosalicylic acid for Sale > 99% USP EP 5-Aminosalicylic acid Fast Delivery
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99% USP EP 5-Aminosalicylic acid Fast Delivery

TDS 3 Inquiries

Unit Price: Get Latest Price
CAS No.:

89-57-6

Grade:

Pharmaceutical Grade

Content:

99%

Port:

SHANGHAI

Brand:

HyperChem

Packaging:

10g/bag, 50g/bag, 100g/bags or other quantities

Price valid (until):

2025-10-30

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Name

    5-Aminosalicylic acid

    CAS number

    89-57-6

    Description

    5-Aminosalicylic acid (5-ASA), also known as mesalazine, is an organic compound with both amino and hydroxy functional groups attached to a benzene ring.

    Structural formula

     Shop 99% USP EP 5-Aminosalicylic acid Fast Delivery-Detailed Image 1

    Molecular Formula

    C7H7NO3

    Molecular Weight

    153.14 g/mol

    Appearance

    White powder

    Quality Standard

    99%

    Storage Condition

    Cool dry place( away from the light)

    Shelf Life

    >2 years if stored properly

    Sample package

    Aluminium foil bag

    Commercial package

    Aluminium Tin, Fiber drum

    Origin

    China

    5-Aminosalicylic acid More Info

    5-Aminosalicylic acid (5-ASA), also known as mesalazine, is an organic compound with both amino and hydroxy functional groups attached to a benzene ring. This structural configuration gives it unique anti-inflammatory properties specifically active in the gastrointestinal tract. First identified as the active therapeutic component of sulfasalazine, 5-ASA was subsequently developed as a standalone medication to provide targeted treatment with improved tolerability. The compound works locally in the intestinal mucosa through multiple mechanisms, including inhibition of prostaglandin and leukotriene production, scavenging of reactive oxygen species, and interference with inflammatory cell function. Its development as various oral and topical formulations represents a significant advancement in targeted gastrointestinal therapy.

     

    Uses and Applications

    The primary application of 5-aminosalicylic acid is in the treatment of inflammatory bowel diseases, particularly ulcerative colitis and Crohn's disease. It is formulated into various delivery systems including pH-dependent release tablets, time-release capsules, suppositories, and enemas to ensure targeted delivery to different segments of the gastrointestinal tract. The medication acts topically on the colonic mucosa to reduce inflammation and maintain remission in mild to moderate inflammatory bowel disease. Additionally, it finds application in dermatology for certain skin conditions and in research as a biochemical reagent. The development of specialized delivery systems has been crucial to protecting 5-ASA from absorption in the upper GI tract and ensuring its therapeutic action in the colon.

     

    Application Market

    The market for 5-aminosalicylic acid is well-established within the gastroenterology pharmaceutical sector, with multiple branded and generic products available worldwide. It is considered a first-line therapy for ulcerative colitis and is included in the World Health Organization's List of Essential Medicines. The market includes both prescription formulations and specialized compounding preparations, with distribution through hospital pharmacies, retail pharmacies, and specialty distributors. Geographic market patterns show variations in preferred formulation types, with different delivery technologies dominating in North American, European, and Asian markets. The competitive landscape features both originator companies and numerous generic manufacturers, with ongoing development of improved delivery systems and combination products.

     

    Important Considerations

    Clinical use of 5-aminosalicylic acid requires appropriate formulation selection based on disease location and severity. Patients should be monitored for potential adverse effects including renal function impairment, although this is uncommon with modern formulations. Important precautions include evaluation of renal function before initiation and during long-term therapy, particularly in patients with pre-existing renal conditions. The medication should be used with caution in patients with salicylate sensitivity and may interact with certain medications including azathioprine and nonsteroidal anti-inflammatory drugs. Storage conditions must maintain product stability, with protection from moisture and light for certain formulations. Patients should receive comprehensive education regarding proper administration techniques, especially for rectal formulations, to ensure optimal therapeutic outcomes.


    Package Image

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    FAQ

    Q1. Can I get a free sample?

    We can send you a samll free sample, and you only need to pay for the shipping cost.


    Q2. What is the HyperChem payment term?

    T/T in advance
    LC at sight
    DP at sight

    Bank transfer

    PayPal

    Bitcoin...


    Q3. What is HyperChem shipment policy?

    Our policy is to strive for the quickest shipment time possible.

    For ready stock samples, they are usually shipped within 3 working days after payment received.
    For non-ready stock, please contact HyperChem sales team to negotiate.


    Q4. What is HyperChem shipment term?

    By Express  
    FedEx  UPS  DHL  EMS                               
    Fast: 3-7 days around, high cost, door to door service

    By Air                                        
    Suitable for more than 50kg 
    Fast: 3-7 days, hight cost, port to port, professional broker needed 

    By Sea
    Suitable for more than 500kg      
    Fast: 7-45 days, low cost, port to port, professional broker needed 


    We will always attempt to utilize the quickest and most affordable way for customers to receive orders. And follow -up with customers via email for all shipment details as well as updated track information until it arrives without damage.


    Q5. What HyperChem will provide after shipment?

    For sample orders: 
    After shipment is done, an timely email including:

    1. Track details (Fedex /TNT/DHL/EMS Track number)
    2. Packaging photo
    3. COA, MSDS, etc
    4. Dispatch date & Estimated arriving time
    5. Shipping invoice

    For commercial orders
    A full set of shipment documents as well as package photos can be provided in scan-copy and original, to help customers complete the customs clearance process.



    Company Profile

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to cater to the requirements of our diverse range of clients.


    Among them, our key client industrial sectors around the global are:

    Pharmaceuticals
    Nutrition Ingredients/ Dietary supplements
    Cosmetic Ingredients
    Food Ingredients
    Veterinary API
    Agriculture fertilizer
    Custom Synthesis lab supply


    HyperChem provides to its wonderful and honorable clients comprehensive purchasing and distribution services which ensure that we are delivering the right generic, raw, or customized product, make sure that we are delivering it at the right time, ensure that it is delivered in the specified amount, and in the right kind of packaging to clients and customers of all types of industries irrespective of their size of operation.




    Certificates

    Basic Info
    Product Name:

    5-Aminosalicylic acid

    Other Name:

    Benzoic acid,5-amino-2-hydroxy-;Salicylic acid,5-amino-;5-Amino-2-hydroxybenzoic acid;2-Hydroxy-5-aminobenzoic acid;3-Carboxy-4-hydroxyaniline;Pentasa;Mesalamine;5-Aminosalicylic acid;Mesalazine;Asacol;5-ASA;Salofalk;Claversal;Asacolitin;Salozinal;Mesacol;Asacolon;Fisalamine;Lixacol;Mesasal;m-Aminosalicylic acid;Rowasa;NSC 38877;Canasa;Ipocol;Asalit;Lialda;Mesalsal;Novo-5 ASA;Colasa;Apriso;Mezavant;Rovasa;Fivasa;Delzicol;61513-32-4

    CAS No.:

    89-57-6

    Molecular Formula:

    C7H7NO3

    InChIKeys:

    InChIKey=KBOPZPXVLCULAV-UHFFFAOYSA-N

    Molecular Weight:

    153.14

    Exact Mass:

    153.14

    BRN:

    2090421

    EC Number:

    201-919-1

    UNII:

    4Q81I59GXC

    NSC Number:

    759301|38877

    DSSTox ID:

    DTXSID5024506

    NCI Thesaurus Code:

    C29249

    Color/Form:

    White to pinkish crystals

    ATC Code:

    A07EC02|A - Alimentary tract and metabolism

    HScode:

    2922509090

    Categories:

    Antispasticity Agents

    Characteristics
    PSA:

    83.6

    XLogP3:

    1.3

    Appearance:

    off-white to gray tablets

    Density:

    1.5±0.1 g/cm3

    Melting Point:

    283 °C

    Boiling Point:

    403.9ºC at 760 mmHg

    Flash Point:

    279-281°C

    Refractive Index:

    1.691

    Water Solubility:

    H2O: <0.1 g/100 mL at 21 ºC;soluble in dimethyl sulfoxide.

    Storage Conditions:

    2-8°C

    Vapor Pressure:

    6.10X10-8 mm Hg at 25 deg C (est)

    Toxicity:

    Peritoneal-mouse LD50: 5000 mg/kg; oral-mouse LDL0: 313 mg/kg

    Flammability characteristics:

    Flammable; burning produces toxic nitrogen oxide fumes

    Henrys Law Constant:

    Henry's Law constant = 5.02X10-12 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    Mesalamine's production and use in the manufacture of light-sensitive paper, azo and sulfur dyes and as a gastrointestinal medication may result in its release to the environment through various waste streams. If released to air, an estimated vapor pressure of 6.1X10-8 mm Hg at 25 °C indicates mesalamine will exist in both the vapor and particulate phases in the atmosphere. Vapor-phase mesalamine will be degraded in the atmosphere by reaction with photochemically-produced hydroxyl radicals; the half-life for this reaction in air is estimated to be 18 hrs. Particulate-phase mesalamine will be removed from the atmosphere by wet or dry deposition. Mesalamine does contain chromophores that absorb at wavelengths >290 nm and therefore may be expected to be susceptible to direct photolysis by sunlight. If released to soil, mesalamine is expected to have very high mobility based upon an estimated Koc of 10. Estimated pKa values of 2.09, 5.26 and 13.64 indicate that this compound will dissociate to the zwitterion form in the environment. Volatilization from moist soil surfaces is not expected to be an important fate process based upon an estimated Henry's Law constant of 5.0X10-12 atm-cu m/mole. Mesalamine is considered completely biodegradable under anaerobic conditions as was indicated by 95.6% methane production following acclimation. If released into water, mesalamine is not expected to adsorb to suspended solids and sediment based upon the estimated Koc. Volatilization from water surfaces is not expected to be an important fate process based upon this compound's estimated Henry's Law constant. An estimated BCF of 3 suggests the potential for bioconcentration in aquatic organisms is low. Hydrolysis is not expected to be an important environmental fate process since this compound lacks functional groups that hydrolyze under environmental conditions. Occupational exposure to mesalamine may occur through inhalation and dermal contact with this compound at workplaces where mesalamine is produced or used. Use data indicate that the general population may be exposed to mesalamine via dermal contact with products containing this compound as well as via ingestion following administration of drugs containing mesalamine, a gastrointestinal anti-inflammatory. (SRC)

    Collision Cross Section:

    134.7 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

    Experimental Properties:

    Decomposes at approx 280 °C|Hydroxyl radical reaction rate constant = 2.09X10-11 cu cm/molec-sec at 25 °C (est)

    Air and Water Reactions:

    Sensitive to moisture. Water insoluble.

    Reactive Group:

    Acids, Carboxylic

    Reactivity Profile:

    5-AMINOSALICYLIC ACID is incompatible with acids, acid chlorides, acid anhydrides, chloroformates and strong oxidizers. (NTP, 1992)

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Skin sensitization, Category 1

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H315 Causes skin irritation

    H317 May cause an allergic skin reaction

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P272 Contaminated work clothing should not be allowed out of the workplace.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P333+P317 If skin irritation or rash occurs: Get medical help.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Commercially available oral mesalamine delayed-release tablets should be stored at a controlled room temperature of 20-25 deg C, while the commercially available oral extended-release capsules should be stored at 25 deg C but may be exposed to temperatures ranging from 15-30 deg C.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

  • Inquiry History
    3 Inquiries
    Country Product Purchase Quantity Date Posted
    India

    Mesalazine cas 89-57-6 5-aminosalicylic acid USP42 EP8.6

    5 MT Aug 24, 2023
    United States

    5-aminosalicylic acid

    1 KG Apr 17, 2025
    United Kingdom

    5-Aminosalicylic acid 98% solid

    40 G May 8, 2026
    Post an enquiry for this product
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