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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > GUANFACINE HCL for Sale > GUANFACINE HCL 98% white powder 29110-48-3
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GUANFACINE HCL 98% white powder 29110-48-3

11 Inquiries

Unit Price: Get Latest Price
CAS No.:

29110-48-3

Content:

99%

Port:

shanghai

Brand:

BELIEVE

Packaging:

25kg

Sample Available:

Yes

Price valid (until):

2025-11-09

This product has been removed from the shop temporarily..
Company Type:
Distributor
Location:
China
Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

(R)-3-hydroxypyrrolidine hydrochloride,(R)-Glycidyl butyrate,fine chemicals,2-dibromo-4,5-difluorobenzene,(S)-(+)-Mandelic acid

  • Product Details

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Guanfaxin hydrochloride is a central antihypertensive drug with pharmacological effects similar to those of colchicine. It is a central alpha-2 receptor activator that activates the central alpha-2 receptor, reduces peripheral sympathetic nervous activity, and leads to a decrease in blood pressure. The antihypertensive effect of this medicine is weaker than that of colchicine. Therefore, the dosage is 7-10 times higher than that of colchicine, and the sedative effect of the central nervous system is also weaker, and the site of action may be different from that of colchicine.


    Company Detail  


    Shandong Believe Chemical Pte. Ltd, is a high-tech enterprise specializing in the R&D, production, and sales of pharmaceutical intermediates, fine chemicals, electronic material intermediates, and dye intermediates. Based in one of China’s key chemical industry hubs, the company leverages strong technical expertise, stringent quality control systems, and comprehensive customer service to become a trusted supplier for global partners in related sectors.

    Core Business Areas
    Pharmaceutical Intermediates

    Supplies high-purity, advanced intermediates such as fluorobenzene, boronic acid, and heterocyclic compounds, tailored for innovative and generic drug synthesis.

    Fine Chemicals

    Provides customized fine chemicals for catalysts, surfactants, and specialty additives to meet precise industrial process requirements.

    Electronic Material Intermediates

    Offers critical high-purity intermediates (e.g., fluorine/sulfur-containing compounds) for semiconductors, LCDs, photoresists, and new energy battery materials.

    Dye Intermediates

    Manufactures key intermediates for high-performance, eco-friendly dyes and pigments, ensuring vibrant color and consistent quality.

    Our Strengths
    R&D-Driven Innovation: A dedicated team and advanced laboratory enable continuous process optimization and custom synthesis capabilities.

    Stringent Quality Assurance: Full-process quality control from raw materials to finished products ensures high purity, consistency, and reliability.

    Integrated Production Capacity: Modern facilities support seamless scaling from pilot to large-scale production, guaranteeing stable supply.

    Customer-Centric Approach: Competitive pricing, flexible supply chain solutions, and professional technical support foster long-term partnerships.

    Vision & Values
    Guided by the principles of Innovation, Quality, and Responsibility, Shandong Billy Fluorine Chemical aims to deliver superior chemical products and services worldwide, positioning itself as a leader in the fine chemical industry.

    Contact Us:
    For inquiries and collaboration, we welcome you to reach out. Let’s create success together.
    ECHEMI Editorial Reference
    Guanfacine Hcl, an anti-hypertensive agent, is a selective α2A-adrenoceptor agonist with Kd of 31 nM and displays 60-fold selectivity over α2B-adrenoceptors. IC50 Value: 31 nM(Kd)Target: Adrenergic ReceptorGuanfacine is a sympatholytic. It is a selective α2A receptor agonist. These receptors are concentrated heavily in the prefrontal cortex and the locus coeruleus, with the potential to improve attention resulting from interaction with receptors in the former. Guanfacine lowers both syst
    Guanfacine hydrochloride is a member of acetamides. It has a role as a geroprotector.|Guanfacine Hydrochloride is the hydrochloride salt form of guanfacine, a centrally acting alpha-2 adrenergic agonist with antihypertensive activity. Alpha-2 receptor stimulation by guanfacine hydrochloride results in a decreased sympathetic outflow from the vasomotor center to the heart, kidneys, and peripheral vasculature. This leads to a decrease in heart rate and peripheral vascular resistance. (NCI05)|A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
    ChEBI: Guanfacine hydrochloride is a member of acetamides. It has a role as a geroprotector.
    Guanfacine hydrochloride,N-(aminoiminomethyl)-2,6-dichlorobenzeneacetamide(Tenex), is structurally related to clonidine hydrochloride andguanabenz acetate and shares many of their pharmacologicalproperties. The drug has a longer duration of action than eitherclonidine hydrochloride or guanabenz acetate. It lasts upto 24 hours. It also requires much longer (8–12 hours) for apeak effect to occur after the drug is administered.

    Basic Info
    Product Name:

    GUANFACINE HCL

    Other Name:

    bs100-141;estulic;lon798;n-(aminoiminomethyl)-2,6-dichlorobenzeneacetamidehydrochloride;n-(aminoiminomethyl)-2,6-dichloro-benzeneacetamidmonohydrochloride;n-amidino-2-(2,6-dichlorophenyl)acetamidehydrochloride;N (AMINOIMINOMETHYL)-2,6-DICHLOROBENZENEACETAMIDE HYDROCHLORIDE SALT;[(2,6-DICHLOROPHENYL)ACETYL]GUANIDINE HYDROCHLORIDE

    CAS No.:

    29110-48-3

    Molecular Formula:

    C9H9Cl2N3O.ClH

    InChIKeys:

    DGFYECXYGUIODH-UHFFFAOYSA-N

    Molecular Weight:

    282.55

    Exact Mass:

    280.988953

    EC Number:

    249-443-3

    UNII:

    PML56A160O

    NSC Number:

    759121

    DSSTox ID:

    DTXSID2045157

    NCI Thesaurus Code:

    C47550

    Color/Form:

    white

    ATC Code:

    C02AC02

    HScode:

    2925294500

    Characteristics
    PSA:

    81.5

    XLogP3:

    3.53850

    Appearance:

    white

    Melting Point:

    215-217℃

    Water Solubility:

    H2O: soluble 12mg/mL at60°C

    Storage Conditions:

    Store at RT

    Toxicity:

    LD50 in mice: 165 mg/kg orally (Coward)

    Critical Temperature & Pressure:

    Inert atmosphere,Room Temperature

    Hazard Identification

    Classification of the substance or mixture

    Acute toxicity - Category 3, Oral

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H301 Toxic if swallowed

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    Response

    P301+P316 IF SWALLOWED: Get emergency medical help immediately.

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Distributor

    Main Products:

    (R)-3-hydroxypyrrolidine hydrochloride,(R)-Glycidyl butyrate,fine chemicals,2-dibromo-4,5-difluorobenzene,(S)-(+)-Mandelic acid

    Location:

    Room 2231, Zhigu Industrial Park, Building 1, North of East Planning Road, East Gaoxin 2nd Road, Weifang Comprehensive Bonded Zone, Shandong Province

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    101-200

    Year of Establishment:

    2020

    Company Certificates
    • Shandong Fantai Refined Biotechnology Co., LtdSGS SGS
    • Shandong Fantai Refined Biotechnology Co., LtdISO ISO
  • Inquiry History
    11 Inquiries
    Country Product Purchase Quantity Date Posted
    Germany

    GUANFACINE HCL

    1 G Oct 15, 2026
    Germany

    Guanfacine HCL

    1000 MG Sep 6, 2026
    Greece

    GUANFACINE HCL 98% white powder

    500 MG May 1, 2026
    United States

    guanfacine hydrochloride

    1 G Apr 13, 2026
    Bangladesh

    Guanfacine Hydrochloride

    1 KG Mar 10, 2026
    United Kingdom

    Guanfacine HCL

    2 G May 11, 2024
    Greece

    Guanfacine HCl

    500 MG Apr 30, 2026
    United States

    Guanfacine hydrochloride

    1 G Oct 25, 2025
    United States

    GUANFACINE HCL

    2 G Oct 6, 2025
    Russia

    n-(aminoiminomethyl)-2,6-dichloro-benzeneacetamidmonohydrochloride

    160 MT Jun 22, 2026
    South Korea

    Donephezil

    100 MG Jul 2, 2024
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