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API Wedelolactone

Name: API Wedelolactone
Brand: Hyper Chem
SKU: pr2510271067
Price: 300 USD
Availability: InStock

3 Inquiries

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CAS No.:

527-09-3

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

Hyper Chem

Packaging:

20kg/Drum 25kg/Drum

Price valid (until):

2025-11-27

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Hangzhou Hyper Chemicals Limited

Company Type:

Trader

Location:

China

Qualification:

Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

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Product Description
Seller Information
Inquiry History

Description

Name	Wedelolactone
CAS number	527-09-3
Description	Wedelolactone, also known as IKK Inhibitor II, is a coumarin ether with significant hepatoprotective effects. Wedelolactone Attenuates Pulmonary Fibrosis Partly Through Activating AMPK and Regulating Raf-MAPKs Signaling Pathway. Wedelolactone suppresses cell proliferation and migration through AKT and AMPK signaling in melanoma. Wedelolactone Enhances Odontoblast Differentiation by Promoting Wnt/β-Catenin Signaling Pathway and Suppressing NF-κB Signaling Pathway
Synonym	Wedelolactone; IKK Inhibitor II;
Appearance	Solid powder
Quality Standard	USP, EP, BP, CP
Shipping Condition	Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Shelf Life	>2 years if stored properly
Sample package	Aluminium foil bag
Commercial package	Aluminium Tin, Fiber drum
Origin	China

Wedelolactone More Info

Wedelolactone is a natural furanocoumarin compound, primarily isolated from plants of the Eclipta genus (such as Eclipta prostrata) and other species in the Asteraceae family.

Basic Information

Chemical Classification: Furanocoumarin derivative.

Molecular Formula: C₁₆H₁₀O₇.

Molecular Weight: 314.24 g/mol.

Source: Mainly extracted from traditional Chinese medicinal herbs like Eclipta prostrata (known as "Han Lian Cao" in Chinese medicine) and Wedelia chinensis.

Key Biological Activities

Estrogenic Activity: Acts as a selective estrogen receptor modulator (SERM), with weak estrogen-like effects that may regulate endocrine balance.

Anti-inflammatory & Antioxidant Effects: Inhibits the release of inflammatory factors and scavenges free radicals, exerting protective effects on cells.

Hepatoprotective Function: Studies indicate it can alleviate liver cell damage and promote liver tissue repair, which aligns with its traditional use in protecting the liver.

Potential Anticancer Activity: In vitro experiments show it may inhibit the proliferation of certain cancer cells, but relevant in vivo research and clinical applications are still in the exploratory stage.

Research & Application Status

Current Focus: Most research remains in the preclinical stage, focusing on its pharmacological mechanisms and activity verification in cell and animal models.

Traditional Application: In traditional Chinese medicine, plants containing wedelolactone are used to treat conditions such as liver and kidney deficiency, hematemesis, and bleeding due to trauma.

Future Prospects: It has potential for development in fields like endocrine regulation, anti-inflammatory drugs, and liver protectants, but further clinical trials are needed to confirm its safety and efficacy in humans.

Shop API Wedelolactone-Detailed Image 1

Basic Info

Product Name:

Bis(D-gluconato-κO1,κO2)copper

Other Name:

Copper,bis(D-gluconato-κO1,κO2)-;Gluconic acid,copper(2+) salt (2:1),D-;Copper,bis(D-gluconato-O1,O2)-;D-Gluconic acid,copper complex;Bis(D-gluconato-κO1,κO2)copper;Cupric gluconate;Gluconic acid,copper(2+) salt;D-Gluconic acid,copper(2+) salt;Copper(II) gluconate;Helshas Cu;Labicuper;115841-02-6;6020-31-1;79366-36-2;92266-74-5

CAS No.:

527-09-3

Molecular Formula:

C12H22CuO14

InChIKeys:

InChIKey=OCUCCJIRFHNWBP-IYEMJOQQSA-L

Molecular Weight:

453.84

Exact Mass:

453.030548

EC Number:

208-408-2

UNII:

RV823G6G67

DSSTox ID:

DTXSID4035960

NCI Thesaurus Code:

C80050

Color/Form:

Light blue crystalline powder

HScode:

2918160000

Categories:

Saccharides

Characteristics

PSA:

283

Melting Point:

155-157 °C

Boiling Point:

673.6°C at 760 mmHg

Flash Point:

375.2ºC

Refractive Index:

16.5 ° (C=1, H2O)

Water Solubility:

H2O: slightly soluble

Flammability characteristics:

Combustible, fire spews spicy and irritating smoke

Specific rotation:

Specific optical rotation: +15 deg at 26 °C (concn = 1 g/100 ml water) /D-form/

Odor:

Odorless

See More Bis(D-gluconato-κO1,κO2)copper Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin sensitization, Sub-category 1B

Specific target organ toxicity â repeated exposure, Category 2

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H317 May cause an allergic skin reaction H373 May cause damage to organs through prolonged or repeated exposure H400 Very toxic to aquatic life H411 Toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P260 Do not breathe dust/fume/gas/mist/vapours/spray. P273 Avoid release to the environment.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P333+P317 If skin irritation or rash occurs: Get medical help. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P319 Get medical help if you feel unwell. P391 Collect spillage.
Storage	none
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

See More Bis(D-gluconato-κO1,κO2)copper Safety Data Sheet 

Seller Information

Business Type:
Trader

Main Products:
Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

Location:
Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
10

Total Annual Revenue:
$5 million-$10 million

Total Employees:
11-50

Year of Establishment:
2013

Certifications:
Certification Report by Bureau Veritas

About HyperChem

Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

Our Competitiveness

One-stop supply

Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

Among all the pharmaceuticals,

90% of them with GMP certificates,

85% of them with DMF files and

50% of them passed FDA approval,

30% get CEP certificate

20% are new R&D products.

Custom Repackaging Service

We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

Quality Control/Quality Assurance

HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

Professional

Transparent Communication

Fast Reaction,

Professional Suggestion

Beyond Expectation.

We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

Inquiry History

3 Inquiries

Country	Product	Purchase Quantity	Date Posted
South Korea	Copper Gluconate	5000 KG	Jan 23, 2024
Portugal	Copper Hepta Gluconate	10	Jan 12, 2024
Paraguay	Eprinomectina	3 KG	Apr 23, 2026

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API Wedelolactone

Product Description

Seller Information