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Home > Biochemical Engineering > Polypeptide > Somatulina for Sale > API Lanreotide acetate
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API Lanreotide acetate

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CAS No.:

127984-74-1

Grade:

Pharmaceutical Grade

Content:

99%

Port:

shanghai

Brand:

Hyper Chem

Packaging:

20kg/Drum 25kg/Drum

Price valid (until):

2025-11-27

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

  • Product Description

  • Seller Information

  • Description

    Name

    Lanreotide acetate

    CAS number

    127984-74-1 (acetate)

    Description

    Lanreotide, a long-acting somatostatin analog, demonstrated potent preclinical activity by binding selectively to somatostatin receptor subtypes sst2 and sst5 with high affinity (IC₅₀ ~0.5–1.0 nM). In rodent models, lanreotide inhibited growth hormone release by up to 80% and reduced insulin and glucagon secretion dose-dependently. In rat pancreatic tumor models, lanreotide significantly suppressed tumor growth and hormone secretion, with up to 60% reduction in tumor volume. Additionally, in xenograft models of neuroendocrine tumors, lanreotide reduced proliferation markers and prolonged survival, supporting its development for acromegaly and hormone-dependent tumors.

    Synonym

    Somatulin; Lanreotide Autogel; Lanreotide acetate; Somatuline LP; Somatuline Depot; Somatuline Autogel; BIM-23014C

    Appearance

    Solid powder

    Quality Standard

    USP, EP, BP, CP

    Shipping Condition

    Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

    Storage Condition

    Dry, dark and at 0 - 4 for short term (days to weeks) or -20 for long term (months to years).

    Shelf Life

    >2 years if stored properly

    Sample package

    Aluminium foil bag

    Commercial package

    Aluminium Tin, Fiber drum

    Origin

    China


    Lanreotide acetate More Info

    Lanreotide acetate is a synthetic long-acting somatostatin analog, primarily used in the treatment of neuroendocrine tumors and acromegaly.

    Basic Information

    Generic Name: Lanreotide acetate

    Drug Class: Somatostatin analogs

    Mechanism of Action: It binds to somatostatin receptors on target cells, inhibiting the secretion of various hormones. This includes growth hormone (GH) and insulin-like growth factor-1 (IGF-1) in acromegaly, as well as vasoactive intestinal peptide (VIP), serotonin, and other hormones in neuroendocrine tumors.

    Main Indications

    Acromegaly: Used to control symptoms and reduce levels of growth hormone and insulin-like growth factor-1 in patients with acromegaly who are unresponsive to surgery or radiation therapy, or as a first-line treatment.

    Neuroendocrine Tumors: Indicated for the symptomatic treatment of unresectable, well-differentiated gastroenteropancreatic neuroendocrine tumors (GEP-NETs) and carcinoid tumors, relieving symptoms such as flushing and diarrhea.

    Thyrotropin-Secreting Pituitary Adenomas (TSHomas): Used to reduce thyroid-stimulating hormone (TSH) levels and control thyroid function in patients with this type of adenoma.

    Administration and Dosage

    Route of Administration: Subcutaneous injection or intramuscular injection of long-acting depot formulations.

    Dosage Characteristics: The dosage is individualized based on the patient's disease type, severity, and treatment response. Long-acting formulations can be administered once every 4 weeks or 8 weeks, improving patient compliance.

    Adverse Reactions

    Common Reactions: Gastrointestinal symptoms such as diarrhea, nausea, abdominal pain, and constipation; injection site reactions including pain, redness, and swelling; and metabolic changes like hyperglycemia or hypoglycemia.

    Less Common Reactions: Gallstone formation (due to inhibition of gallbladder contraction), bradycardia, and fatigue. Regular monitoring of gallbladder status is recommended during treatment.


    Shop API Lanreotide acetate-Detailed Image 1

    Basic Info
    Product Name:

    Somatulina

    Other Name:

    10-(4-aminobutyl)-19-[(2-amino-3-naphthalen-2-yl-propanoyl)amino]-N-(1 -carbamoyl-2-hydroxy-propyl)-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol -3-ylmethyl)-6,9,12,15,18-pentaoxo-7-propan-2-yl-1,2-dithia-5,8,11,14, 17-pentazacycloicosane-4-carboxamide;Somatulina;3-(2-Naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide cyclic (2→7)-disulfide acetate;Angiopeptin acetate

    CAS No.:

    127984-74-1

    Molecular Formula:

    C54H69N11O10S2

    InChIKeys:

    PUDHBTGHUJUUFI-UHFFFAOYSA-N

    Molecular Weight:

    1096.3 g/mol

    Exact Mass:

    1155.488159

    Categories:

    Polypeptide

    Characteristics
    PSA:

    406 Ų

    Appearance:

    white to off-white

    Storage Conditions:

    -20°C

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H361 Suspected of damaging fertility or the unborn child

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Pharmaceuticals,Peptide,Cosmetics,Nutritional Supplements

    Location:

    Rm. 803, Tower 4, LOFT49 Creative City Pioneer Zone, No.88 Jiru Rd. Gongshu Dist., Hangzhou, 310015 ZJ, China

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    10

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    11-50

    Year of Establishment:

    2013

    Certifications:

    Certification Report by Bureau Veritas

    About HyperChem

    Established in 2013, Hyper Chem has exclusive tie-ups with leading manufacturers, supplying raw materials produced in GMP and ISO 9002 certified facilities, and provides high-quality ingredients and raw materials to meet the needs of a diverse range of pharmaceutical cosmetics ingredients and nootropic supplements companies worldwide.

    Our Competitiveness

    One-stop supply

    Wide Range Of products including pharmaceutical, Cosmetic Ingredients and nootropic supplements

    Among all the pharmaceuticals,

    90% of them with GMP certificates,

    85% of them with DMF files and

    50% of them passed FDA approval,

    30% get CEP certificate

    20% are new R&D products.

    Custom Repackaging Service


    We can efficiently repackage your material into sample sizes, custom batch-specific sizes, or semi-bulk package sizes according to your specifications. And ensures the product is packaged in a quality-controlled environment and will maintain its integrity throughout every stage of the process.

    Quality Control/Quality Assurance


    HyperChem is committed to delivering on its promises of top-quality products with verified quality data.

    All materials are vigorously inspected by the factory and/or outsourced analytical laboratories to ensure each and every lot meets or exceeds our reference standards.

    Trade assurance service with 100% payment protection, It is best achieved by delivering products and services 100% right the first time, on time, every time.

    Professional

    Transparent Communication

    Fast Reaction,

    Professional Suggestion

    Beyond Expectation.

    We have exclusive partnerships with research and production facilities across the country and we offer varied pharmaceutical services in the most cost-efficient way. The production facilities are GMP, WHO-GMP, EU GMP and US FDA approved and are backed by strong regulatory support such as Dossier, DMF, Tech Pack and relevant Stability studies for regulatory filings.

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