4-IODO-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID 75092-30-7

Focusing on innovative research, development, and production in the field of fine chemicals, we prioritize technology, quality, and market orientation. We collaborate with global partners to build a high-tech chemical industry chain and promote sustainable development in the industry.

The company's main products include pharmaceutical intermediates, food additives, essence, spices and plant extracts. The products have passed international certification and are exported to Europe, America, Japan, South Korea and Southeast Asia.

4-IODO-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID Basic information Product Name: 4-IODO-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID Synonyms: 4-IODO-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID;4-Iodo-1-methylpyrazole-5-carboxylic Acid;4-iodo-1-methyl-1H-pyrazole-5-carboxylic acid(SALTDATA: FREE);4-Iodo-1-methyl-1H-pyrazole-5-carboxylic acid 98%;5-Carboxy-4-iodo-1-methyl-1H-pyrazole, 4-Iodo-2-methyl-2H-pyrazole-3-carboxylic acid;4-iodo-2-methylpyrazole-3-carboxylic acid;4-Iodo-1-methyl-1H-pyrazole-5-carboxylicacid98%;4-Iodo-1-methylpyrazole-5-carboxylicAcid> CAS: 75092-30-7 MF: C5H5IN2O2 MW: 252.01 EINECS: Product Categories: HFC00039 Mol File: 75092-30-7.mol 4-IODO-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID Chemical Properties Melting point  242°C(lit.) Boiling point  362.2±27.0 °C(Predicted) density  2.26±0.1 g/cm3(Predicted) storage temp.  2-8°C(protect from light) pka 1.76±0.37(Predicted) form  powder to crystal color  White to Almost white CAS DataBase Reference 75092-30-7 Safety Information HazardClass  IRRITANT HS Code  2933199090 MSDS Information 4-IODO-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID Usage And Synthesis Synthesis 1354705-42-2 75092-30-7 General procedure for the synthesis of 4-iodo-1-methyl-1H-pyrazole-5-carboxylic acid from ethyl 4-iodo-1-methyl-1H-pyrazole-5-carboxylate: to a stirred solution of ethyl 4-iodo-1-methyl-1H-pyrazole-5-carboxylate (700 mg, 2.5 mmol) in a solvent mixture of 15 mL MeOH/H2O/THF (v/v/v = 1:1:1) Lithium hydroxide monohydrate (1.05 g, 25 mmol) was added. After addition, the reaction solution was stirred at 25°C for 2 hours. After the completion of the reaction, the mixture was concentrated under reduced pressure and the pH was adjusted to 4 with 1N HCl. The aqueous phase was extracted with EtOAc, and the organic layers were combined, washed with saturated brine, dried over anhydrous Na2SO4, and concentrated under reduced pressure to obtain the crude 4-iodo-1-methyl-1H-pyrazole-5-carboxylic acid (623.0 mg, crude yield 98%), which was used directly in the next step without further purification. The crude product was directly used in the next step without further purification. References [1] Patent: US2014/200215, 2014, A1. Location in patent: Paragraph 1002; 1006 4-IODO-1-METHYL-1H-PYRAZOLE-5-CARBOXYLIC ACID Preparation Products And Raw materials Raw materials Ethyl 4-iodo-1-methyl-1H-pyrazole-5-carboxylate-->Hydrochloric acid-->Tetrahydrofuran-->Water-->Lithium hydroxide monohydrate-->Methanol



——  Q&A  ——

Q1:Do you provide sample?

A: Yes, we can provide free sample, you only need pay the shipping cost.

Q2: What is the lead time?

A: For stock goods, it usually take about 5-7 days by air, 15-30 days by sea,For customized products, the delivery time needs to be confirmed based on the actual situation.

Q3: How can I buy? What is the payment method?

A: You can contract us through Email or you can browse our website:orientchem.cc, we have bank transfer,

A：We attach great importance to after-sales service of our products. If there are any quality issues, please contact us within 30 days of receiving the goods and we will handle returns and exchanges for you.