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Home > Active Pharmaceutical Ingredients > Other Chemical Drugs > Rapamycin for Sale > Pharmaceutical API Powder CAS 53123-88-9 Rapamycin
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Pharmaceutical API Powder CAS 53123-88-9 Rapamycin

29 Inquiries

Unit Price:

$100/G FOB

Get Latest Price
CAS No.:

53123-88-9

Grade:

Pharmaceutical Grade

Content:

99%

Port:

qingdao

Brand:

JF

Packaging:

according to your request

Price valid (until):

2027-11-30

Company Type:
Trader
Location:
Hongkong, China
Qualification:
Main Products:

Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

  • Product Description

  • Seller Information

  • Inquiry History

  • Description

    Product Description

                             99% Purity Raw Material Powder 53123-88-9 Rapamycin



    Item Specifications
    Assay ,%     98.0% to 102.0% calculated trans- and cis-Stereoisomer of Sirolimus on the dried basis 
    Appearance White crystalline powder 
    Loss On Dry  Not More Than 0.50%
    Heavy Metals  Not More Than 0.002%
    Individual Impurity  Not More Than 1.0%
    Total Impurities  Not More Than 2.0%
    Cis-Stereoisomer of Sirolimus  Not More Than 5.0%
    Ethanol  ≤5000PPM
    Acetonemia ≤5000PPM

    Rapamycin is produced by the soil bacterium Streptomyces hygroscopicus. The drug's name comes from Rapa Nui, the indigenous name of Easter Island, where the compound was originally discovered in soil samples in the 1970s.
    Sirolimus, also known as rapamycin, is a macrolide compound that is used to coat coronary stents, prevent organ transplant rejection and treat a rare lung disease called lymphangioleiomyomatosis. It has immunosuppressant functions in humans and is especially useful in preventing the rejection of kidney transplants.

    Application:

    Rapamycin is a triene macrolide antibiotic, which demonstrates anti-fungal, anti-inflammatory, anti-tumor and immunosuppressive properties. Rapamycin has been shown to block T-cell activation and proliferation, as well as, the activation of p70 S6 kinase and exhibits strong binding to FK-506 binding proteins.

    Rapamycin also inhibits the activity of the protein, mTOR, (mammalian target of rapamycin) which functions in a signaling pathway to promote tumor growth. Rapamycin binds to a receptor protein (FKBP12) and the rapamycin/FKB12 complex then binds to mTOR and prevents interaction of mTOR with target proteins in this signaling pathway.

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    FAQ

    Q1: Are you the manufacturer or trade company?
    --We are the manufacturer in China, founded on 2011.

    Q2: When will the product be shipped after payment?
    --The parcel will be get ready and shipped within 1 day.

    Q3: How long will it take to receive the parcel?
    --3-5days for the US market; 3-7days for the others.

    Q4: What can I do if I don't have the ability to clear the custom.
    --We got experience after doing export for many years, so don't worry we can handle that.

    Q5: Why should you buy from us not from other suppliers?
    ---Jinan Jianfeng Chemical Co.,Ltd is a medium-sized enterprise integrating the development, production, sales and export and import trade of chemical products. Our factory has perfect infrastructure, advanced processing technology and completed detection means.

    Basic Info
    Product Name:

    Rapamycin

    Other Name:

    Rapamycin;23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine,rapamycin deriv.;Antibiotic AY 22989;[3S-[3R*[S*(1R*,3S*,4S*)],6S*,7E,9S*,10S*,12S*,14R*,15E,17E,19E,21R*,23R*,26S*,27S*,34aR*]]-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone;23,27-Epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone,9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-,[3S-[3R*[S*(1R*,3S*,4S*)],6S*,7E,9S*,10S*,12S*,14R*,15E,17E,19E,21R*,23R*,26S*,27S*,34aR*]]-;(3S,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,34aS)-9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-Hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexamethyl-23,27-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone;AY 22989;(-)-Rapamycin;Sirolimus;SIIA 9268A;Rapamune;Rapammune;RPM;NSC 226080;RAPA;Wy 090217;Cypher;Nab rapamycin;Supralimus;14S-Rapamycin;Cypher Bx Velocity;PNP-sirolimus;DE 109;MS-RO01;MS-RO02;MS-RO03;Perceiva;Rapamysin;SVP-R;1179372-35-0;1189166-54-8;1233221-34-5;1353039-01-6

    CAS No.:

    53123-88-9

    Molecular Formula:

    C51H79NO13

    InChIKeys:

    InChIKey=QFJCIRLUMZQUOT-HPLJOQBZSA-N

    Molecular Weight:

    914.18

    Exact Mass:

    914.17

    EC Number:

    262-640-9

    HScode:

    2942000000

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    195

    XLogP3:

    6

    Appearance:

    yellow solid

    Density:

    1.2±0.1 g/cm3

    Melting Point:

    183-185 °C

    Boiling Point:

    973°C at 760 mmHg

    Flash Point:

    87 °C

    Refractive Index:

    1.551

    Water Solubility:

    soluble in DMSO at 50mg/ml or methanol at 25mg/ml. soluble in alcohol, dimethyl sulfoxide and dimethyl formamide. Insoluble in water.ethanol: soluble 2 MM

    Storage Conditions:

    -20°C

    Vapor Pressure:

    0.56 hPa ( 20 °C)

    Toxicity:

    LD50 in mice (mg/kg): 600 i.p.; >2,500 orally (Vézina)

    Specific rotation:

    D25 -58.2° (methanol)

    Hazard Identification

    Classification of the substance or mixture

    Carcinogenicity, Category 2

    Reproductive toxicity, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H351 Suspected of causing cancer

    H361 Suspected of damaging fertility or the unborn child

    H372 Causes damage to organs through prolonged or repeated exposure

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P318 IF exposed or concerned, get medical advice.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

    Location:

    Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $50 million-$100 million

    Total Employees:

    51-100

    Year of Establishment:

    2012

    We have more than 10 years experience in the pharmacy filed. Mainly manufactures pharmaceutical APIs,Pharmaceutical intermediate and Cosmetic raw material. Owing to the good quality and competitive price, we have a very good reputation in China's pharmaceutical circles.

    In the principle of "Quality Oriented", Jianfeng passed the certification of ISO9001:2008 Quality Management System.

    Our products are based on bulk, high volume, wholesale price, third party testing, certificate reporting, and bring high quality ingredients to many domestic and overseas enterprises.

    "Honesty, practicality, innovation, development" are our values. Jianfeng would like to cooperate with you with high quality products and competitive price.

  • Inquiry History
    29 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Supply Medical Grade High Purity Rapamycin Powder CAS 53123-88-9 Rapamycin

    100 G Aug 16, 2023
    United States

    Raw Pharmaceutical Grade Material Rapamycin Powder CAS 53123-88-9 with High Purity

    100 G Jul 6, 2023
    Hungary

    Raw Pharmaceutical Grade Material Rapamycin Powder CAS 53123-88-9 with High Purity

    100 G Nov 20, 2023
    India

    Raw Pharmaceutical Grade Material Rapamycin Powder CAS 53123-88-9 with High Purity

    1000 MT Nov 18, 2023
    Germany

    Raw Pharmaceutical Grade Material Rapamycin Powder CAS 53123-88-9 with High Purity

    100 G Sep 7, 2023
    United States

    TNJONE High quality GMP Certificated 99% Purity Sirolimus Rapamycin 53123-88-9 in Stock

    1 G Jan 1, 2025
    United States

    Rapamycin Powder

    2 KG Aug 25, 2023
    Paraguay

    Rapamycin Sirolimus Powder

    1 G Feb 21, 2024
    India

    Rapamycin

    1 MT Feb 12, 2026
    India

    Rapamycin

    1.00 KG Jan 26, 2024
    United States

    Rapamycin

    50 MG Apr 17, 2026
    United States

    rapamycin

    100 G Sep 27, 2025
    Philippines

    Rapamycin

    5 G Feb 10, 2025
    Australia

    Rapamycin

    99 KG Nov 3, 2024
    United States

    Rapamycin

    10 MT May 22, 2024
    Canada

    Rapamycin

    1 KG Jan 24, 2025
    United States

    Rapamycin

    1 KG Nov 27, 2024
    United States

    rapamycin

    1 G Jul 12, 2024
    India

    Rapamycin

    1 KG Jun 28, 2024
    United States

    Rapamycin

    1 KG Apr 14, 2025
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