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Promethazine hydrochloride 99.9% powder CAS: 58-33-3

Name: Promethazine hydrochloride 99.9% powder CAS: 58-33-3
Brand: Belibeve
SKU: pr2512151006
Price: 1 USD
Availability: InStock

13 Inquiries

Unit Price: Get Latest Price 

CAS No.:

58-33-3

Grade:

Medical Grade

Content:

99%

Port:

shanghai

Brand:

Belibeve

Packaging:

25kg/Drum

Price valid (until):

2026-01-15

Contact Supplier

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Shan Dong Believe Chemical Pte. Ltd.

Company Type:

Distributor

Location:

China

Qualification:

Main Products:

(R)-3-hydroxypyrrolidine hydrochloride,(R)-Glycidyl butyrate,fine chemicals,2-dibromo-4,5-difluorobenzene,(S)-(+)-Mandelic acid

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Product Description
Seller Information
Inquiry History

Description

Product Detail

Indications: It can competitively block the Hl receptor in the limbs and produce antihistamine effects. It can counteract capillary dilation caused by histamine, reduce its permeability, alleviate wheezing caused by bronchial smooth muscle contraction, and has a stronger and more lasting effect than diphenhydramine hydrochloride.

Company Detail

Shandong Believe Chemical Pte. Ltd, is a high-tech enterprise specializing in the R&D, production, and sales of pharmaceutical intermediates, fine chemicals, electronic material intermediates, and dye intermediates. Based in one of China’s key chemical industry hubs, the company leverages strong technical expertise, stringent quality control systems, and comprehensive customer service to become a trusted supplier for global partners in related sectors.

Core Business Areas

Pharmaceutical Intermediates

Supplies high-purity, advanced intermediates such as fluorobenzene, boronic acid, and heterocyclic compounds, tailored for innovative and generic drug synthesis.

Fine Chemicals

Provides customized fine chemicals for catalysts, surfactants, and specialty additives to meet precise industrial process requirements.

Electronic Material Intermediates

Offers critical high-purity intermediates (e.g., fluorine/sulfur-containing compounds) for semiconductors, LCDs, photoresists, and new energy battery materials.

Dye Intermediates

Manufactures key intermediates for high-performance, eco-friendly dyes and pigments, ensuring vibrant color and consistent quality.

Our Strengths

R&D-Driven Innovation: A dedicated team and advanced laboratory enable continuous process optimization and custom synthesis capabilities.

Stringent Quality Assurance: Full-process quality control from raw materials to finished products ensures high purity, consistency, and reliability.

Integrated Production Capacity: Modern facilities support seamless scaling from pilot to large-scale production, guaranteeing stable supply.

Customer-Centric Approach: Competitive pricing, flexible supply chain solutions, and professional technical support foster long-term partnerships.

Vision & Values

Guided by the principles of Innovation, Quality, and Responsibility, Shandong Billy Fluorine Chemical aims to deliver superior chemical products and services worldwide, positioning itself as a leader in the fine chemical industry.

For inquiries and collaboration, we welcome you to reach out. Let’s create success together.

Basic Info

Product Name:

Promethazine hydrochloride

Other Name:

10H-Phenothiazine-10-ethanamine,N,N,α-trimethyl-,hydrochloride (1:1);Phenothiazine,10-[2-(dimethylamino)propyl]-,monohydrochloride;10H-Phenothiazine-10-ethanamine,N,N,α-trimethyl-,monohydrochloride;10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride;Plletia;Promethazine hydrochloride;Phenergan;Promethazine chloride;Promethazine monohydrochloride;Atosil;Fenergan;Diprazin;Pipolfen;Diprasine;Romergan;Pipolphen;Romergan hydrochloride;Kinetosin;Pyrethia;Promethazinium chloride;Phena;Promasun;Hiberna;Phencen;Dorme;Phenergan VC;Fellozine;Remsed;Lergigan;Genphen;Prorex;Fenazil;Anergan 25;Anergan 50;Duplamin;Prothazine;Mepergan;Provigan;Phanergan D;NSC 231688;Himazin;16639-38-6;88208-28-0

CAS No.:

58-33-3

Molecular Formula:

C17H20N2S.ClH

InChIKeys:

InChIKey=XXPDBLUZJRXNNZ-UHFFFAOYSA-N

Molecular Weight:

320.88

Exact Mass:

320.111389

EC Number:

200-375-2

NSC Number:

757301|231688

DSSTox ID:

DTXSID3021192

HScode:

2933699090

Categories:

Bulk Drug Intermediates

Characteristics

PSA:

31.8

XLogP3:

5.10640

Appearance:

Promethazine hydrochloride is an odorless white to faint yellow crystalline powder. Bitter taste. A 10% solution in water has a pH of 3.5-5.0. (NTP, 1992)

Density:

1.131 g/cm3

Melting Point:

230-232 °C

Boiling Point:

403.7ºC at 760 mmHg

Flash Point:

9℃

Water Solubility:

In water, 1.56X10-2 g/L (15.6 mg/L) at 24 deg C

Storage Conditions:

Refrigerator

Vapor Pressure:

1.03X10-5 mm Hg at 25 deg C (est)

Toxicity:

LD50 i.v. in mice: 55.0 mg/kg (Rajsner)

Collision Cross Section:

162.7 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

Air and Water Reactions:

Slowly oxidizes in air, acquiring a blue color. Also turns blue on exposure to moisture. Water soluble.

Reactive Group:

Amines, Phosphines, and Pyridines

Reactivity Profile:

PROMETHAZINE HYDROCHLORIDE is sensitive to light. In aqueous solution, it is degraded by heat and light (more rapidly in air or oxygen). Incompatible with alkalis and alkaline solutions such as those of aminophylline, soluble barbiturates and phenytoin sodium. Iron(III) and copper(III) accelerate the degradation (NTP, 1992).

See More Promethazine hydrochloride Properties 

Hazard Identification

Classification of the substance or mixture

Acute toxicity - Category 4, Oral

Skin irritation, Category 2

Skin sensitization, Category 1

Eye irritation, Category 2

Acute toxicity - Category 4, Inhalation

Specific target organ toxicity â single exposure, Category 3

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

GHS label elements, including precautionary statements

Precautionary statement(s)
Pictogram(s)
Signal word	Warning
Hazard statement(s)	H302 Harmful if swallowed H315 Causes skin irritation H317 May cause an allergic skin reaction H319 Causes serious eye irritation H332 Harmful if inhaled H335 May cause respiratory irritation H411 Toxic to aquatic life with long lasting effects
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/... P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment.
Response	P301+P317 IF SWALLOWED: Get medical help. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P317 If skin irritation occurs: Get medical help. P362+P364 Take off contaminated clothing and wash it before reuse. P333+P317 If skin irritation or rash occurs: Get medical help. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P317 Get medical help. P319 Get medical help if you feel unwell. P391 Collect spillage.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

Other hazards which do not result in classification

no data available

Handling and Storage

Precautions for safe handling

Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

Conditions for safe storage, including any incompatibilities

Promethazine hydrochloride preparations should be protected from light. Promethazine hydrochloride oral solution and tablets should be stored in tight, light-resistant containers at 15-30 and 20-25 deg C, respectively, while the rectal suppositories should be stored in well-closed containers at 2-8 deg C. Freezing of the oral solution should be avoided. Following the date of manufacture, commercially available promethazine preparations have expiration dates of 2-5 years depending on the dosage form and manufacturer.

See More Promethazine hydrochloride Safety Data Sheet 

Seller Information

Business Type:
Distributor

Main Products:
(R)-3-hydroxypyrrolidine hydrochloride,(R)-Glycidyl butyrate,fine chemicals,2-dibromo-4,5-difluorobenzene,(S)-(+)-Mandelic acid

Location:
ROOM 574 JIUDINGFENG LARGE BUILDING NO.888 CHANGBAISHAN ROAD QINGDAO AREA CHINA (SHANDONG) PILOT FREE TRADE ZONE

Payment Terms:
TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

Average lead Time:
7

Total Annual Revenue:
$1 million-$2.5 million

Total Employees:
101-200

Year of Establishment:
2020

Certifications:
ISO,SGS

Inquiry History

13 Inquiries

Country	Product	Purchase Quantity	Date Posted
Singapore	Promethazine hydrochloride CAS 58-33-3 with High purity 99% White powder 58-33-3 SENYI	1 KG	Jun 29, 2023
United Kingdom	Promethazine hydrochloride CAS 58-33-3 with High purity 99% White powder 58-33-3 SENYI	25 MT	Jun 17, 2023
United States	Hot Selling CAS 58-33-3 Promethazine hydrochloride with 99% Purity White Powder	1 MT	Nov 6, 2023
United States	Promethazine HCl	1	Jun 3, 2025
Canada	Promethazine hcl	1 KG	Jan 2, 2024
Argentina	Promethazine hydrochloride	50 G	Apr 15, 2026
United Kingdom	Promethazine HCL 99.9% powder	1	Jan 10, 2026
United States	Promethazine Hydrochloride	20 G	Apr 10, 2025
Kenya	promethazine Hcl	40 KG	Dec 3, 2024
United States	Promethazine	1 KG	Jan 5, 2026
United States	USA UK Canada Europe etc 99% Pure Promethazine HCl Hydrochloride Powder CAS 58- 33-3 Safe Shipping	1 KG	Dec 14, 2025
Netherlands	Promethazine HCl	100 G	Mar 11, 2025
India	Promethazine Hydrochloride	25 G	Oct 9, 2024

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