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Top quality product L-Carnosine

42 Inquiries

Unit Price: Get Latest Price
CAS No.:

305-84-0

Grade:

Industrial Grade

Content:

99%

Port:

Qingdao

Brand:

N/A

Packaging:

1kg/bag;25kg/drum

Price valid (until):

2026-02-27

Company Type:
Trader
Location:
Hongkong, China
Qualification:
Main Products:

Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  


    Introduction to L-Carnosine

    L-Carnosine is a naturally occurring dipeptide molecule composed of two amino acids, beta-alanine and L-histidine. It is found in high concentrations in specific tissues of the body, particularly in skeletal muscle and the brain. It is classified as a "geroprotector" due to its multi-faceted role in combating age-related cellular damage.

    Here are its key characteristics and benefits, broken down point by point:

    1. Potent Antioxidant and Anti-Glycation Agent:

      • This is one of its primary functions. L-Carnosine acts as a powerful, broad-spectrum antioxidant that neutralizes free radicals.

      • Crucially, it is highly effective at inhibiting the formation of Advanced Glycation End-products (AGEs). AGEs are harmful compounds formed when sugars bind to proteins (like collagen and elastin), making them stiff and dysfunctional. This process is a major contributor to skin aging and loss of elasticity.

    2. Natural Metal Chelator:

      • L-Carnosine can bind to (chelate) certain metal ions, such as copper and zinc. This is important because these ions can catalyze oxidative reactions and contribute to the formation of harmful free radicals. By chelating them, Carnosine further reduces oxidative stress in the body and skin.

    3. Cellular Senescence and Telomere Protection:

      • Research suggests that L-Carnosine can help delay cellular senescence—the state where cells stop dividing and enter a state of permanent growth arrest.

      • It appears to have a protective effect on telomeres, the protective caps at the ends of chromosomes that shorten with each cell division, which is a key marker of cellular aging.

    4. Benefits for Skin Health and Anti-Aging:

      • By fighting glycation and oxidation—the two key processes that damage collagen and elastin—L-Carnosine helps to preserve skin's firmness, elasticity, and youthful structure.

      • It helps to prevent the formation of cross-linked collagen, which is stiff and dysfunctional, thereby reducing the appearance of wrinkles and fine lines.

      • Its anti-glycation action also helps to prevent the yellowing and sallowness associated with aged skin.

    5. Systemic Health Benefits:

      • Muscle Function: High concentrations in muscle tissue suggest a role in buffering acid (regulating pH) during exercise, which can help reduce fatigue and improve performance.

      • Brain Health: It may have neuroprotective properties, helping to protect neurons from oxidative stress and the toxic effects of metal ions, which are implicated in age-related cognitive decline.

      • Eye Health: It is also found in the lens of the eye, where its antioxidant properties are thought to help protect against cataract formation.

    6. Primary Applications in Products:

      • Skincare: Used in anti-aging serums, creams, and lotions aimed at improving skin firmness and reducing wrinkles by protecting structural proteins.

      • Dietary Supplements: Marketed for anti-aging, exercise performance, and brain health support.

      • Eye Health Formulations: Included in some supplement blends designed to support vision health.

    ECHEMI Editorial Reference
    Crystalline
    Solid
    Carnosine is a dipeptide that is the N-(beta-alanyl) derivative of L-histidine. It has a role as an anticonvulsant, an antioxidant, an antineoplastic agent, a human metabolite, a Daphnia magna metabolite, a mouse metabolite, a neuroprotective agent and a geroprotector. It is a conjugate acid of a carnosinate. It is a tautomer of a carnosine zwitterion.|Carnosine has been investigated for the treatment of Gulf War Illness.|Carnosine is a dipeptide comprised of a beta-alanine and a 3-methyl-L-histidine, which is found in dietary red meat, with potential antioxidant, metal-chelating and anti-glycation activities. Carnosine scavenges both reactive oxygen species (ROS) and unsaturated aldehydes produced by cell membrane lipid peroxidation. Additionally, this dipeptide may reduce the rate of formation of advanced glycation end-products (AGE). Altogether, this may protect cells against oxidative damage. In addition, carnosine is able to chelate toxic metals.|A naturally occurring dipeptide neuropeptide found in muscles.
    L-Carnosine is a dipeptide composed of β-alanine and L-histidine that has been found in rat olfactory bulb, skeletal muscle, brain, kidney, and spleen tissues, as well as human skeletal muscle, and has diverse biological activities. It is a metal chelator that forms complexes with copper, cobalt, nickel, cadmium, or zinc. Dietary administration of L-carnosine (60 mg/kg per day) reduces plasma levels of advanced glycation end products (AGEs) in diabetic rats. It reduces brain edema, blood-brain barrier disruption, microglial activation, and neuronal apoptosis in a rat model of intracerebral hemorrhage when administered at a dose of 1,000 mg/kg. L-Carnosine (250, 500, and 1,000 mg/kg, i.p.) reduces hepatic protein carbonylation and necrosis in a rat model of cirrhosis induced by bile duct ligation. It also reduces lung myeloperoxidase (MPO) activity, production of reactive oxygen species (ROS), and TNF-α and IL-6 levels, as well as alveolar hemorrhage, interstitial edema, and pulmonary leukocyte infiltration in a mouse model of LPS-induced lung injury.
    white to off-white crystalline.

    Basic Info
    Product Name:

    L-Carnosine

    Other Name:

    N-B-ALANYL-L-HISTIDINE;H-BETA-ALA-HIS-OH;L-IGNOTINE;L-BETA-ALANINE HISTIDINE;L-CARNOSINE;B-ALANYL-L-HISTIDINE;BETA-A-H;BETA-ALANYL-L-HISTIDINE

    CAS No.:

    305-84-0

    Molecular Formula:

    C9H14N4O3

    InChIKeys:

    CQOVPNPJLQNMDC-ZETCQYMHSA-N

    Molecular Weight:

    226.23

    Exact Mass:

    226.23

    BRN:

    87671

    EC Number:

    206-169-9

    UNII:

    8HO6PVN24W

    TSCA:

    TSCA listed

    DSSTox ID:

    DTXSID7048615

    NCI Thesaurus Code:

    C118880

    Color/Form:

    White

    HScode:

    29332900

    Characteristics
    PSA:

    121

    XLogP3:

    -4

    Appearance:

    White crystalline

    Density:

    1.2673 (rough estimate)

    Melting Point:

    253 °C (dec.) (lit.)

    Boiling Point:

    367.84°C (rough estimate)

    Flash Point:

    350.7ºC

    Refractive Index:

    21 ° (C=2, H2O)

    Water Solubility:

    almost transparency

    Storage Conditions:

    2-8°C

    Vapor Pressure:

    0Pa at 25℃

    Toxicity:

    LD50 oral in mouse: > 14930mg/kg

    Flammability characteristics:

    Thermal decomposition to emit toxic nitrogen oxide fumes

    Specific rotation:

    20.9 º (c=1.5, H2O)

    Odor:

    at 100.00%. odorless

    PKA:

    2.62(at 25℃)

    Collision Cross Section:

    151 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|149.72 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|152.18 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|154.1 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|154.93 Ų [M-H]- [CCS Type: DT, Method: stepped-field]|150.8 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|154.7 Ų [M+Na]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|152.1 Ų [M-H]- [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|153.1 Ų [M-H]-

    Critical Temperature & Pressure:

    -20°C

    Hazard Identification

    Classification of the substance or mixture

    Not classified.

    GHS label elements, including precautionary statements

    Pictogram(s) No symbol.
    Signal word

    No signal word

    Hazard statement(s)

    none

    Precautionary statement(s)
    Prevention

    none

    Response

    none

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Weight Loss Peptide,Reta,Tirz,Sema,5 Amino 1mq,Cosmetic raw material,API,SLU-PP-332

    Location:

    Unit D01,3/F., Wong King Industrial Building,No.2 Tai Yau Street, Kowloon

    Payment Terms:

    TT against copy of documents,D/P,L/C,D/A,O/A,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7

    Total Annual Revenue:

    $50 million-$100 million

    Total Employees:

    51-100

    Year of Establishment:

    2012

    We have more than 10 years experience in the pharmacy filed. Mainly manufactures pharmaceutical APIs,Pharmaceutical intermediate and Cosmetic raw material. Owing to the good quality and competitive price, we have a very good reputation in China's pharmaceutical circles.

    In the principle of "Quality Oriented", Jianfeng passed the certification of ISO9001:2008 Quality Management System.

    Our products are based on bulk, high volume, wholesale price, third party testing, certificate reporting, and bring high quality ingredients to many domestic and overseas enterprises.

    "Honesty, practicality, innovation, development" are our values. Jianfeng would like to cooperate with you with high quality products and competitive price.

  • Inquiry History
    42 Inquiries
    Country Product Purchase Quantity Date Posted
    Russia

    L-Carnosine CAS 305-84-0

    50 KG Jan 13, 2026
    India

    L-Carnosine

    20.00 MT Dec 13, 2023
    India

    L-Carnosine

    10.00 KG Dec 12, 2023
    India

    L-Carnosine

    1.00 KG Oct 11, 2025
    India

    L-Carnosine

    10.00 MT Dec 15, 2023
    India

    L-Carnosine

    20.00 MT Dec 13, 2023
    Australia

    L-Carnosine

    1000 G Aug 4, 2026
    India

    L-Carnosine

    1 KG Aug 4, 2026
    India

    L-Carnosine

    100 KG Jul 10, 2026
    India

    L-Carnosine

    25.00 KG Jun 29, 2026
    India

    L-Carnosine

    1.00 KG Jun 4, 2026
    India

    L-Carnosine

    1.00 KG May 28, 2026
    India

    L-Carnosine

    25.00 KG Mar 9, 2026
    India

    L- Carnosine

    150.00 KG Jan 21, 2026
    India

    L-Carnosine

    500.00 KG May 30, 2025
    Australia

    L-Carnosine

    1 KG Sep 30, 2024
    Russia

    carnosine L

    100 KG Mar 11, 2024
    Hungary

    L-Carnosine

    1 KG Jul 6, 2026
    Netherlands

    L-Carnosine

    15 KG Jun 24, 2026
    India

    L-Carnosine

    1.00 KG May 28, 2026
    Post an enquiry for this product
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