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Jinlan 98+ EP/BP/USP Dabrafenib buy - large image1
Jinlan 98+ EP/BP/USP Dabrafenib buy - image1

Jinlan 98+ EP/BP/USP Dabrafenib

Unit Price: Get Latest Price
CAS No.:

1195765-45-7

Grade:

medical grade

Content:

98%

Port:

Shanghai/Ningbo/Qingdao

Brand:

Jinlan

Packaging:

25kg/Cardboard Drum

Price valid (until):

2026-04-01

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Peptides,API,Intermediate

  • Product Description

  • Seller Information

  • Description


      Product Detail  


    Basic Product Description


    CAS Number: 1195765-45-7

    Chemical Name: N-[3-[5-(2-Aminopyrimidin-4-yl)-2-(1,1-dimethylethyl)-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide

    Molecular Formula: C₂₃H₂₀F₃N₅O₂S₂

    Molecular Weight: 519.56 g/mol

    Synonyms: Tafinlar®, GSK2118436, Dabrafenib free base

    Related Categories: BRAF Kinase Inhibitor, Oral Tyrosine Kinase Inhibitor (TKI), MAPK Pathway Inhibitor, Melanoma Therapeutic Small Molecule

    Key Highlight: A potent, selective inhibitor of mutated BRAF V600 kinase; approved for the treatment of BRAF V600 mutation-positive unresectable or metastatic melanoma, non-small cell lung cancer, and anaplastic thyroid cancer; blocks the MAPK signaling pathway to inhibit tumor cell proliferation and survival.

    Basic Info
    Product Name:

    Dabrafenib

    Other Name:

    Benzenesulfonamide,N-[3-[5-(2-amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro-;N-[3-[5-(2-Amino-4-pyrimidinyl)-2-(1,1-dimethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide;Dabrafenib;GSK 2118436;Dabarefenib;Tafinlar;GSK 436;N-[3-[5-(2-Aminopyrimidin-4-yl)-2-tert-butyl-1,3-thiazol-4-yl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide;Tafmlar

    CAS No.:

    1195765-45-7

    Molecular Formula:

    C23H20F3N5O2S2

    InChIKeys:

    InChIKey=BFSMGDJOXZAERB-UHFFFAOYSA-N

    Molecular Weight:

    519.5624096

    Exact Mass:

    519.56

    EC Number:

    1592732-453-0

    Categories:

    Other Chemical Drugs

    Characteristics
    PSA:

    148

    XLogP3:

    4.8

    Density:

    1.4±0.1 g/cm3

    Boiling Point:

    653.7±65.0°C at 760 mmHg

    Flash Point:

    349.2±34.3 °C

    Refractive Index:

    1.626

    Water Solubility:

    very slightly soluble at pH 1

    PKA:

    -1.5None

    Hazard Identification

    Classification of the substance or mixture

    Reproductive toxicity, Category 2

    Specific target organ toxicity – repeated exposure, Category 2

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H361 Suspected of damaging fertility or the unborn child

    H373 May cause damage to organs through prolonged or repeated exposure

    H400 Very toxic to aquatic life

    H411 Toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P203 Obtain, read and follow all safety instructions before use.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P273 Avoid release to the environment.

    Response

    P318 IF exposed or concerned, get medical advice.

    P319 Get medical help if you feel unwell.

    P391 Collect spillage.

    Storage

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Peptides,API,Intermediate

    Location:

    Room 606, Building 1, Fu Yi Commercial Center, Shangcheng District, Hangzhou City, Zhejiang Province - 1

    Payment Terms:

    100% TT in advance

    Average lead Time:

    275

    Total Annual Revenue:

    $1 million-$2.5 million

    Total Employees:

    51-100

    Year of Establishment:

    2020

    Hangzhou Jinlan Pharm-Drugs Technology Co., Ltd (with its export company Hangzhou Royall Import & Export Co.,Ltd.) is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int' l Airport and Shanghai Pudong Int' l Airport, the transportation and production environment are excellent. JINLAN PHARMA mainly business includes: 1) API, Pharmaceutical Intermediates, CMO, CRO, CDMO and so on. 2) Pharmaceutical Equipment such as: Distilled Water Machinery, Mixer, Sterilizer and so on.

    JINLAN PHARM focus on:

    ■ Contrast Agent

    ■ Anti-COVID APIs

    ■ Respiratory System APIs

    ■ Anti-tumor & Anti-Cancer APIs

    ■ Anti-Diabetes APIs

    ■ Anti-HCV & Anti-HBV APIs

    ■ Anti-HIV APIs

    ■ Peptides

    ■ Pharmaceutical Intermediates

    ■ CMO, CRO, CDMO

  • Country Product Purchase Quantity Date Posted
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