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Home > Cosmetic Ingredient > Bleaching Agent > Nicotinamide for Sale > Cosmetic Ingredient Powder nicotinic acid Vitamin B3 Nicotinemide CAS 98-92-0 Niacinamide
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Cosmetic Ingredient Powder nicotinic acid Vitamin B3 Nicotinemide CAS 98-92-0 Niacinamide

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Unit Price: Get Latest Price
CAS No.:

98-92-0

Grade:

Cosmetics Grade

Content:

99%

Port:

shenzhen

Brand:

HS

Packaging:

25kg drum

Price valid (until):

2026-04-04

Company Type:
Manufactory
Location:
China
Payment Terms:
L/C,TT against B/L draft before shipment,100% TT in advance
Average Lead Time:
7 days
Qualification:
Main Products:

Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive

  • Product Description

  • Seller Information

  • Inquiry History

  • Description


      Product Detail  












    whasapp:+8615202961574
    Email:gary@xahnb.com

    Items Specifications
    Product Name High quality Cosmetic Ingredient Powder Vitamin B3 Nicotinemide CAS 98-92-0 Niacinamide
    MF C6H6N2O
    CAS 98-92-0

    Nicotinamide(Vitamin B3, Vitamin PP) is a very stable vitamin which offers a wide range of benefits. Nicotinamide is a component of NAD and NADP, essential coenzymes in ATP production, also having a central role in DNA repair and skin homeostasis. It is a significant niacin derivative, mainly occurring in many organisms. Nicotinamide can produce coenzyme Ⅰ and Ⅱ when it reacts with ribose, adenine and phosd. Also it boosts the synthesis of DNA, fats and proteins and improves the energy metabolism of cells. So it can greatly prevent melanin deposition, and reduce discoloration. It has an effective whitening function. Nowadays, as a natural cosmetics ingredient, it is widely applied in skin and hair care products.

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    Key Technical Parameters:

    Appearance White crystalline powder
    Assay 99.0~101.0%
    pH (10% aqueous solution) 5.5~7.5
    Melting range

    128.0~131.0℃

    Residue on ignition ≤0.1%(wt%)
    Heavy metals ≤20ppm
    Identification Complies
    Readily carbonizable Complies
    Loss on drying ≤0.5%

    Application:

    • UV and blue light-stressed Skin Care

    • Helps protect from UV and blue light damage for beautiful and healthy looking skin

    • Reduces the appearance of lines and wrinkles

    • Improves the elasticity of the skin

    • Rebalances uneven skin tone

    • Reduces discoloration

    • Pollution Care

    • Protects against damage from urban pollutants for beautiful and healthy skin

    • Blemish Care

    • Blemish-free, shine-free, refined skin appearance

    • Resilience to external damage and reduced skin sensitivity

    • Well moisturized skin, comfortable skin feeling

    • Nicotinamide PC shows skin lightening properties versus placebo in 3D skin model.

    Key Benefits of Niacinamide in Skincare

    *Improves Skin Barrier Function:Niacinamide helps strengthen the skin’s natural barrier by increasing the production of ceramides and other lipids, which retain moisture and protect against environmental stressors.

    *Reduces Redness and Inflammation:Niacinamide has anti-inflammatory properties, making it effective for calming conditions like acne, rosacea, and eczema.

    *Minimizes Pore Appearance:Regular use of niacinamide can help regulate sebum production, which may reduce the appearance of enlarged pores.

    *Brightens Skin Tone:Niacinamide inhibits the transfer of melanin to skin cells, helping to fade dark spots, hyperpigmentation, and uneven skin tone.

    *Anti-Aging Properties:Niacinamide boosts collagen production, which can reduce the appearance of fine lines and wrinkles, improving skin elasticity.

    *Antioxidant Protection:Nicotinamide helps protect the skin from free radical damage caused by UV exposure and pollution.

    *Acne Control:By regulating oil production and reducing inflammation, Niacinamide can help manage acne and prevent breakouts.

    Benefits:

    • Prevent melanin from depositing into keratinocytes

    Skin will darken when melanin is delivered to keratinocytes. But Nicotinamide can act on generated melanin, and then efficiently prevent the transfer of 35% to 40% of melanin from melanocytes to horny cells. Hence, it can lessen excessive pigmentation. Clinical tests have suggested that Nicotinamide face cream can obviously reduce the brown spots ‘ number and area.

    • Accelerate the metabolism of melanocytes

    Nicotinamide is directly absorbed by cells owing to its small molecules. Nicotinamide can penetrate the inner layer of the skin within 2 hours. Using Nicotinamide to the skin can form energy molecules in human body quickly. It can penetrate the stratum corneum to the connective tissue and fibers between the dermis; and then it directly gets in the bottom of the cell to facilitate the metabolism of cells.

    • Promote synthesis of cortical proteins on skin

    Nicotinamide synthesizes protein on the surface of skin. And it amends skin texture, and moisturizes skin. In 1990, European Patent 0-396-422 shows that it can whiten skin and exert sun block effect to add Nicotinamide, 0.1% to 5% silicone compound and UVA, UVB sunscreen into the cream formulation.





    Items Standard
    Test Results

    Identification

    A.H-NMR:Comply with the structure
    Complies
    B.LC-MS:Comply with the structure
    Complies
    C.The IR spectrum of sample should be identical with that of reference standard.
    Complies
    D.HPLC-ESI-MS
    The retention time of the major peak in the chromatogram of the Assay preparation corresponds to that in the chromatogram of the Standard preparation, as obtained in the Assay.







    Complies
    Loss on drying % ≤2.0
    0.19
    Heavy metals ppm ≤10 
    <10
    Moisture % ≤1.0
    0.1
    Sulphated ash % ≤0.5 determined on 1.0 g.
    0.009
    Residue on ignition % ≤0.1
    0.03

    Related Substances %

    Unspecified impurities: for each impurity ≤0.10 <0.10
    Total Impurity ≤0.5 0.18
    Purity % ≥99.0
    99.7
    Assay % 99.0 ~101.0 (anhydrous substance).
    99.8
    Storage Preserve in well-closed, light-resistant and airtight containers.
    Complies

    Function & Application:
    Niacinamide (vitamin B3) is a very stable vitamin which offers a wide range of well-documented topical benefits. Niacinamide is a component of NAD and NADP, essential coenzymes in ATP production, also having a central role in DNA repair and skin homeostasis.

    Niacinamide (vitamin B3) acts as a moisturizing, antioxidant, anti-aging, anti-acne, lightening & whitening agent. It offers special efficacy for removing dark yellow tone of skin and makes it lighter and brighter. It reduces the appearance of lines, wrinkles and discoloration. It improves the elasticity of the skin and helps to protect from UV damage for beautiful and healthy skin. It gives well moisturized skin and comfortable skin feeling.

    Niacinamide (vitamin B3) is used in whitening creams, lotions, serums, masks, facial cleansers, moisturizing, sun care, anti-aging and anti-acne products.

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    Q1  Can i get some samples
    A1  Yes, we can supply the free sample, but the shipping cost be paid by our customers.
    Q2  How to start orders or make payments
    A2  Proforma invoice will be sent first after confirmation of order, enclosed our bank information.                Payment by T/T,or Paypal or Escrow(Alibaba).
    Q3  How to confirm the Product Quality before placing orders
    A3  You can get free samples for some products,you only need to pay the shipping cost or arrange a   courier to us and take the samples. You can send us your product specifications and requests,we  will manufacture the products according to your requests.
    Q4  What's your MOQ
    A4  Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
    Q5  How about delivery leadtime
    A5  Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
    Q6  Is there a discount
    A6  Different quantity has different discount.
    Q7  How do you treat quality complaint
    A7  First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
    Q8  How to contact us
    A8 You can chat with us by Trademanager,MSN&Skype Online.
           You can choose your interested products and send inquiry to us.
           You can dial our telephone directly or send Email to us., you will get our reply.

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    ECHEMI Editorial Reference
    It is white needle crystal or crystalline powder, no smell or odor slightly, slightly bitter taste. The relative density is 1.4, melting point is 131-132 ℃.1 g of the above the product is soluble in 1 ml of water, 1.5 ml ethanol or 10 ml glycerin, insoluble in ether. The pH of 10% aqueous solution is 6.5-7.5. in dry air to light and heat stability, in alkaline or acidic solution, heating generation to nicotinic acid. Rats by oral LD502.5-3.5g/kg ADI value does not make special provisions (ECC,
    Nicotinamide is a white powder. (NTP, 1992)|DryPowder; OtherSolid|Solid|WHITE CRYSTALLINE POWDER.
    Nicotinamide is a white powder. (NTP, 1992)|Nicotinamide is a pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group. It has a role as an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor, a metabolite, a cofactor, an antioxidant, a neuroprotective agent, an EC 3.5.1.98 (histone deacetylase) inhibitor, an anti-inflammatory agent, a Sir2 inhibitor, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite, a mouse metabolite, a human urinary metabolite and a geroprotector. It is a vitamin B3, a pyridinecarboxamide and a pyridine alkaloid. It derives from a nicotinic acid.|Mediatric is a DEA Schedule III controlled substance. Substances in the DEA Schedule III have a potential for abuse less than substances in Schedules I or II and abuse may lead to moderate or low physical dependence or high psychological dependence.|An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and pellagra. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.|Vitamin B refers to several water soluble vitamins often found together in foods, all of which are necessary for normal growth and metabolism, but none of which are synthesized in adequate amounts by humans. The common forms of vitamin B include vitamin B1 (thiamine), B2 (riboflavin), B3 (niacin), B6 (pyridoxine) and B12 (cyanocobalamin). Except for niacin (when given in high doses), there is no evidence that the other B vitamins, in physiologic or even super-physiologic high doses cause liver injury or jaundice. The major forms of vitamin B and selected other water soluble vitamins (biotin, pantothenic acid, choline) are discussed briefly in this record.|Niacinamide is the active form of vitamin B3 and a component of the coenzyme nicotinamide adenine dinucleotide (NAD). Niacinamide acts as a chemo- and radio-sensitizing agent by enhancing tumor blood flow, thereby reducing tumor hypoxia. This agent also inhibits poly(ADP-ribose) polymerases, enzymes involved in the rejoining of DNA strand breaks induced by radiation or chemotherapy.|An important compound functioning as a component of the coenzyme NAD. Its primary significance is in the prevention and/or cure of blacktongue and PELLAGRA. Most animals cannot manufacture this compound in amounts sufficient to prevent nutritional deficiency and it therefore must be supplemented through dietary intake.

    Certificates

    Basic Info
    Product Name:

    Nicotinamide

    Other Name:

    3-Pyridinecarboxamide;Nicotinamide;Aminicotin;Benicot;Delonin Amide;Dipegyl;NAM;Niacinamide;Nicamindon;Nicofort;Nicotilamide;Nicotine acid amide;Nicotinic acid amide;Nicotinic amide;Nicotylamide;Niocinamide;Niozymin;Pelonin amide;3-Pyridinecarboxylic acid amide;Vi-Nicotyl;Vitamin B3 (niacinamide);Vitamin B;Nicosan 2;3-Carbamoylpyridine;Pelmine;β-Pyridinecarboxamide;Nicobion;Nicosylamide;Nicovit;Niavit PP;Nicovitina;Nicamina;Nicasir;3-(Aminocarbonyl)pyridine;m-(Aminocarbonyl)pyridine;3-Amidopyridine;Papulex;Nictoamide;Pelmin;NSC 13128;NSC 27452;Vitamin B3 (nicotinamide);123574-63-0;37321-14-5;78731-47-2

    CAS No.:

    98-92-0

    Molecular Formula:

    C6H6N2O

    InChIKeys:

    InChIKey=DFPAKSUCGFBDDF-UHFFFAOYSA-N

    Molecular Weight:

    122.12500

    Exact Mass:

    122.12

    EC Number:

    202-713-4

    UNII:

    25X51I8RD4

    DEA Code Number:

    1405

    ICSC Number:

    1703

    NSC Number:

    759115|27452|13128

    DSSTox ID:

    DTXSID2020929

    NCI Thesaurus Code:

    C2327

    Color/Form:

    White, powder, needles from benzene|Colorless crystalline solid|White, crystalline powder|Colorless needles

    ATC Code:

    A11HA01|A - Alimentary tract and metabolism

    HScode:

    2933399090

    Categories:

    Bleaching Agent

    Characteristics
    PSA:

    55.98000

    XLogP3:

    0.88080

    Appearance:

    Nicotinamide is a white powder. (NTP, 1992)

    Density:

    1.400 g/cm3 @ Temp: 25 °C

    Melting Point:

    130 °C

    Boiling Point:

    157 °C @ Press: 5 x 10-4 Torr

    Flash Point:

    182°C

    Refractive Index:

    1.4660 (estimate)

    Water Solubility:

    1000 g/L (20 ºC)

    Storage Conditions:

    Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

    Vapor Pressure:

    Vapour pressure, kPa at 35°C: 3.1

    Vapor Density:

    Relative vapour density (air = 1): 4.2

    Toxicity:

    LD50 s.c. in rats: 1.68 g/kg (Brazda, Coulson)

    Odor:

    Odorless

    Taste:

    Bitter taste

    PH:

    10% "wt in vol" solution in water is neutral to litmus

    PKA:

    3.35(at 20 °C)

    Henrys Law Constant:

    Henry's Law constant = 2.90X10-12 atm-cu m/mol at 25 °C (est)

    Dissociation Constants:

    3.35 (at 20 °C)|pKa = 3.35 (conjugate acid)|kb1 = 2.24X10-11; kb2 = 3.16X10-14

    Collision Cross Section:

    125.3 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with Agilent tune mix (Agilent)]|129.32 Ų [M+H]+ [CCS Type: DT, Method: stepped-field]|137.3 Ų [M+Na]+ [CCS Type: DT, Method: stepped-field]|118 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine]|125.3 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated with ESI Low Concentration Tuning Mix (Agilent)]|121.7 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]|125.2 Ų [M+H]+ [CCS Type: DT, Method: single field calibrated]|126.7 Ų [M+H]+

    Experimental Properties:

    Readily hydrolyzed to free acid by heating in acid or alkaline solution|Forms crystalline salts with acids|Hydroxyl radical reaction rate constant = 2.34X10-12 cu cm/molec sec at 25 °C (est)

    Air and Water Reactions:

    Water soluble.

    Reactive Group:

    Amides and Imides

    Reactivity Profile:

    An amine and amide. Acts as a weak base in solution. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Organic amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx).

    Autoignition Temperature:

    480 °C

    Physical Dangers:

    Dust explosion possible if in powder or granular form, mixed with air.

    Hazard Identification

    Classification of the substance or mixture

    Eye irritation, Category 2

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H319 Causes serious eye irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    Response

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    Storage

    none

    Disposal

    none

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Prevent deposition of dust. Closed system, dust explosion-proof electrical equipment and lighting. Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Separated from oxidants.

  • Seller Information
    Business Type:

    Manufactory

    Main Products:

    Ivermectin,Active pharmaceutical ingredients,Cosmetics material,Chemical intermediate,Nootropic,Food additive

    Location:

    6 floor Baoyilongji Building B Weiyang Area, Fengcheng 8 Road, Xi'an city, Shaanxi, 710000, China

    Payment Terms:

    L/C,TT against B/L draft before shipment,100% TT in advance

    Average lead Time:

    7 days

    Total Annual Revenue:

    $5 million-$10 million

    Total Employees:

    51-100

    Year of Establishment:

    2017

    Company Certificates
    • HNB BiotechISO ISO
    • HNB BiotechISO ISO

    Xi'an Harmonious Natural Bio-Technology Co., Ltd. was founded in 2010, and located in Xian

    International Logistics Industrial Zone, Xi'an City, Shaanxi Province, China. Now it is the

    leading researcher and one of the biggest manufacturer in high technology API area. 

     

    There are 8 experts in our research team. We insist in innovation and produce high quality

    products. And GMP standard workshop and complete stainless extraction equipment. 

    We have 2 sales departments over 20 people and sell our products all over the world.

     

    We also have strong professional research and development team, talented personnel and

    completely equipped laboratory for the quality controlling. Various Detection Device is

    equipped in HNB company, such as HPLC, GC, Spectrophotometer, AAS, Polarimeter, Auto

    titrators, BOD Incubators, COD Incubators, Melting point apparatus and so on.

     

    HNB mainly engaged in export of products including, without limitation, pharmaceutical raw

    materials both for vet and human, also Vitamins, Amino Acids, minerals, peptides, plant

    extract, feed and food additives.

     

    Our company's business is based on Honest, Trustworthy, Constantly to Go Beyond and

    Achieve Mutual Win. Sincerely hope to strengthen exchanges and cooperation with friends

    from both home and abroad.

     

    Passion to innovate, Power to deliver !

  • Inquiry History
    108 Inquiries
    Country Product Purchase Quantity Date Posted
    United States

    Competitive Price CAS 98-92-0 Vitamin B3 Niacinamide 99% white powder 98-92-0

    100 KG Sep 23, 2023
    India

    Nicotinamide   

    45.00 KG Jun 13, 2025
    India

    Nicotinamide  

    25.00 KG Jun 12, 2025
    India

    Nicotinamide

    50.00 KG Jun 11, 2025
    India

    Nicotinamide 

    50.00 KG Jun 13, 2025
    United States

    Niacinamide

    1 KG Feb 5, 2024
    India

    Nicotinamide 

    25.00 KG Jun 11, 2025
    Egypt

    Niacinamide

    1.00 KG Aug 28, 2026
    Russia

    Niacinamide

    1 KG Dec 2, 2024
    India

    Niacinamide

    100.00 KG Aug 3, 2026
    Pakistan

    Niacinamide

    5.00 KG Sep 14, 2026
    Algeria

    Niacinamide

    1.00 KG Sep 17, 2026
    Denmark

    Niacinamide

    5.00 MT Sep 9, 2026
    India

    Niacinamide

    200.00 KG Sep 2, 2026
    India

    Niacinamide

    1.00 KG Aug 31, 2026
    India

    Niacinamide

    1.00 KG Aug 22, 2026
    Nigeria

    Niacinamide

    100.00 KG Aug 20, 2026
    Uganda

    Niacinamide

    500 G Aug 13, 2026
    Pakistan

    Niacinamide

    10.00 MT Jul 10, 2026
    India

    Nicotinamide

    1 KG Jul 1, 2026
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