KissPeptin-10 | China Origin| Factory Direct Supply | 5mg/10mg | Lyophilized Powder for Export | CAS NO: 374675-21-5

• KissPeptin-10 (KP-10) is a decapeptide (10-amino acid peptide) encoded by the KISS1 gene, representing the C-terminal bioactive fragment (residues 45-54) of the full-length Kisspeptin-54 (also known as Metastin) . It is the shortest and most potent form capable of fully activating the Kisspeptin receptor (GPR54/KISS1R) with intrinsic biological activity equivalent to longer Kisspeptin fragments PubMed.
  
  
  • Systematic Name: Kisspeptin-10
  • CAS Number: 374675-21-5
  • Molecular Weight: 1302.45 g/mol
  • Amino Acid Sequence: Tyr-Asn-Leu-Asn-Ser-Phe-Gly-Leu-Arg-Tyr-NH₂ (single-letter: YNLNSFGLRY)
  • Physical Appearance: Sterile filtered white lyophilized (freeze-dried) powder
  
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  Biological Functions:                                                
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• 1、Reproductive Health:
• Central role in puberty initiation and reproductive hormone regulation
  • Potential treatment for hypogonadotropic hypogonadism (HH) and infertility
  • Enhances LH pulse frequency and testosterone production in males PubMed
  • Regulates ovulation and menstrual cycles in females
  
  
• 2、 Oncology:
• Originally identified as a metastasis suppressor gene product for melanoma and breast cancer
  • Inhibits cancer cell migration and invasion in triple-negative breast cancer PMC
  • Induces apoptosis in cancer cells through transcriptional and metabolic reprogramming PMC
  
  
• 3、 Bone Metabolism:
  • Prevents bone loss by suppressing osteoclast activity via Dusp18-mediated Src dephosphorylation PMC
    • Potential therapeutic target for osteoporosis and bone resorption disorders PMC
    
    
  • 4、Metabolic Regulation:
    Links energy balance to reproductive function (e.g., leptin-mediated regulation)
    • May play a role in obesity-related reproductive dysfunction
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  Lyophilization Technology Advantages:         
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  Our KissPeptin-10 undergoes state-of-the-art freeze-drying process that delivers unmatched benefits:

  1、Maximum Activity Retention: Preserves KissPeptin-10's native structure and biological activity by avoiding thermal degradation

  2、 Exceptional Stability: Extends shelf life to 24 months when stored properly (vs. 3-6 months for liquid forms)

  • 3、Enhanced Purity: Removes residual solvents and moisture completely, minimizing degradation factors
  • 4、Easy Reconstitution: Dissolves rapidly in sterile water or saline with no clumping
  • 5、Reduced Contamination Risk: Aseptic manufacturing process ensures product safety

  
  
  

• Basic Information:                                                  

• Item	Details
  Product Name	KissPeptin-10 (human)
  CAS No.	374675-21-5
  Alias	Metastin (45-54), Kp-10
  Sequence	Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂
  Molecular Formula	C₆₃H₈₃N₁₇O₁₄
  Molecular Weight	1302.45
  Purity	≥99%
  Appearance	White lyophilized powder
  Solubility	Soluble in water, DMSO
  Storage	-20°C, keep dry and sealed

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Company Profile：                                               

LingMi BioTechnology Co., Ltd is a modern advanced enterprise specializing in production and exportation of APIs, Pharmaceutical intermediates, plant extracts etc. Our products are widely used in medicine, health care products, cosmetics, nutritional supplements and food additives areas. With years of experience in the pharmaceutical chemical and biosynthetic industries.It provides compliant, stable and cost-effective core raw materials as well as one-stop CDMO/CMO solutions for global pharmaceutical enterprises and innovative drug R&D institutions.