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Home > Pharmaceutical Intermediates > Bulk Drug Intermediates > Topiramate for Sale > USP Standard White Powder Topiramate CAS 97240-79-4
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USP Standard White Powder Topiramate CAS 97240-79-4

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Unit Price:

$10.3-11.33/MT FOB

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CAS No.:

97240-79-4

Grade:

Chemical Grade

Content:

99%

Port:

shanghai

Brand:

Wuhan pnq

Packaging:

Aluminum foil bag

Price valid (until):

2026-08-01

Company Type:
Trader
Location:
China
Qualification:
Main Products:

Apigenin,PQQ,NMNH

  • Product Description

  • Seller Information

  • History Price

  • Inquiry History

  • Description
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    Q1: What's your MOQ?
    A:It depends on different products,we can accept sample order or provide free sample for your test.
    Q2:How about delivery leadtime?
    A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
    Q3: Is there a discount?
    A:Different quantity has different discount.
    Q4:How to start orders or make payments?
    A:Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T or Bitcoin.
    Q5: How do you treat quality complaint?
    A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
    Q6:We don't know you at all, how can we trust you?
    A: You are always warm welcomed to visit us at any time.Before we start B2B, MIC has audited our company on-spot and approved our credit.Commitment is the No.1 Point of our Enterprise's Value.
    Q7:Do you test all your goods before delivery?
    A:Yes, we have 100% test before delivery,International Authorized Third-Party Test for the products if you need are highly welcomed.

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    Description

    Name

    Topiramate

    CAS number

    97240-79-4

    EINECS number

    619-263-3

    Related CAS#

    488127-53-3 (lithium); 97240-79-4 (free base)

    Synonym

    HSDB-7531; HSDB 7531; HSDB7531; Topiramate; Tipiramato; Topax;

    Description

    Topiramate is a sulfamate-substituted monosaccharide molecule that functions as a broad-spectrum antiepileptic drug (AED). Topiramate is effective in treating both partial and generalized seizures, including refractory focal seizures and primary or secondary generalized seizures . It is also used as an adjunctive therapy for conditions such as Lennox-Gastaut syndrome and for preventing neuralgiform attacks. It blocks voltage-gated sodium channels, enhances GABA activity, and inhibits glutamate receptors, particularly AMPA and NMDA receptors. These actions help reduce neuronal excitability, which is crucial for its antiepileptic and vulsant effects. 

    Structure

    \

    Molecular Formula

    C12H21NO8S

    Molecular Weight

    339.36 g/mol

    Appearance

    Solid powder

    Quality Standard

    USP Standard

    Assay

    ≥98%

    Shipping Condition

    Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

    Storage Condition

    Store in cool place. Keep container tightly closed in a dry and well ventilated place.

    Shelf Life

    >2 years if stored properly

    Sample package

    Aluminium foil bag

    Commercial package

    Aluminium Tin, Fiber drum

    Origin

    China

    HS Code

    2932999099


    Topiramate More Info

    Topiramate is an vulsant medication primarily used to treat epilepsy and prevent migraines. It is classified as a sulfamate-substituted monosaccharide and has a unique pharmacological profile that makes it effective for various neurological conditions.

    Mechanism of Action

    Topiramate's mechanism of action is multifaceted and includes:
    Sodium Channel Blockade: It inhibits voltage-dependent sodium channels, stabilizing neuronal membranes and preventing the propagation of seizures.
    GABAergic Activity: Topiramate enhances the activity of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, at certain GABA-A receptor sites, which helps reduce neuronal excitability.
    Glutamate Receptor Antagonism: It inhibits excitatory neurotransmission by blocking AMPA and kainate receptors, further contributing to its vulsant effects.
    Carbonic Anhydrase Inhibition: Topiramate exhibits weak inhibition of carbonic anhydrase isoenzymes, although this action is not considered critical for its vulsant properties.

    Applications

    Epilepsy: Used as an adjunctive treatment for partial-onset seizures in adults and children, as well as for generalized tonic-clonic seizures.
    Migraine Prevention: Approved for the prophylactic treatment of migraines in adults and adolescents.
    Weight Loss: Sometimes used off-label in combination with phentermine for weight management in obesity.

    Routes of Administration

    Topiramate is available in several formulations:
    Oral Tablets: Commonly prescribed in doses ranging from 25 mg to 200 mg.
    Sprinkle Capsules: Designed for patients who may have difficulty swallowing tablets.


    Basic Info
    Product Name:

    Topiramate

    Other Name:

    β-D-Fructopyranose,2,3:4,5-bis-O-(1-methylethylidene)-,1-sulfamate;β-D-Fructopyranose,2,3:4,5-bis-O-(1-methylethylidene)-,sulfamate;5H-Bis[1,3]dioxolo[4,5-b:4′,5′-d]pyran,β-D-fructopyranose deriv.;Topiramate;McN 4853;RWJ 17021;2,3:4,5-Bis-O-(1-methylethylidene) β-D-fructopyranose sulfamate;Topomax;Topamax;Epitomax;Topimax;Topamac;TPM;Epitoma;Topina;Sincronil;Qudexy XR;Trokendi XR;Topiragen;1103510-60-6

    CAS No.:

    97240-79-4

    Molecular Formula:

    C12H21NO8S

    InChIKeys:

    InChIKey=KJADKKWYZYXHBB-XBWDGYHZSA-N

    Molecular Weight:

    339.36

    Exact Mass:

    339.36

    EC Number:

    200-659-6

    HScode:

    29350090

    Characteristics
    PSA:

    124

    XLogP3:

    -0.8

    Appearance:

    white solid

    Density:

    1.336±0.06 g/cm3(Predicted)

    Melting Point:

    125-126 °C

    Boiling Point:

    438.7°C at 760 mmHg

    Flash Point:

    9℃

    Refractive Index:

    1.497

    Water Solubility:

    DMSO: ~44 mg/mL

    Storage Conditions:

    2-8°C

    Vapor Pressure:

    7.0X10-8 mm Hg at 25 deg C (est)

    Toxicity:

    LD50 intraperitoneal in rat: > 1500mg/kg

    Specific rotation:

    D23 -34.0° (c = 0.4 in methanol)

    Taste:

    Bitter

    PH:

    pH= 6.3 (saturated solution)

    PKA:

    8.7None

    Hazard Identification

    Classification of the substance or mixture

    Skin irritation, Category 2

    Eye irritation, Category 2

    Specific target organ toxicity – single exposure, Category 3

    GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H315 Causes skin irritation

    H319 Causes serious eye irritation

    H335 May cause respiratory irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection/hearing protection/...

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    Response

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P321 Specific treatment (see ... on this label).

    P332+P317 If skin irritation occurs: Get medical help.

    P362+P364 Take off contaminated clothing and wash it before reuse.

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P319 Get medical help if you feel unwell.

    Storage

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    P405 Store locked up.

    Disposal

    P501 Dispose of contents/container to an appropriate treatment and disposal facility in accordance with applicable laws and regulations, and product characteristics at time of disposal.

    Other hazards which do not result in classification

    no data available

    Handling and Storage

    Precautions for safe handling

    Handling in a well ventilated place. Wear suitable protective clothing. Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Use non-sparking tools. Prevent fire caused by electrostatic discharge steam.

    Conditions for safe storage, including any incompatibilities

    Store the container tightly closed in a dry, cool and well-ventilated place. Store apart from foodstuff containers or incompatible materials.

  • Seller Information
    Business Type:

    Trader

    Main Products:

    Apigenin,PQQ,NMNH

    Location:

    Room 1006, Building C6, Economic Development Wanda, Caidian District, Wuhan City, Hubei Province

    Payment Terms:

    100% TT in advance

    Average lead Time:

    30

    Total Annual Revenue:

    Less than $1 million

    Total Employees:

    5-10

    Year of Establishment:

    2021

    Wuhan PNQ trade located in Wuhan, China, is an innovative natural products manufacturer and supplier that offers raw powders as dietary ingredients, food and beverage additives, sports nutrition supplements.

  • Weekly Price

    The chart shows the price trend of the product in the past 12 months.

  • Inquiry History
    1 Inquiries
    Country Product Purchase Quantity Date Posted
    Vietnam

    Topiramate

    30 KG Aug 26, 2025
    Post an enquiry for this product
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